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Aliases for TMEM245 Gene
Aliases for TMEM245 Gene
External Ids for TMEM245 Gene
- HGNC: 1363
- Entrez Gene: 23731
- Ensembl: ENSG00000106771
- UniProtKB: Q9H330
Previous HGNC Symbols for TMEM245 Gene
- C9orf5
Previous GeneCards Identifiers for TMEM245 Gene
- GC09M111778
Summaries for TMEM245 Gene
GeneCards Summary for TMEM245 Gene
TMEM245 (Transmembrane Protein 245) is a Protein Coding gene. Diseases associated with TMEM245 include Neuropathy, Hereditary Sensory And Autonomic, Type Iii and Hypermobility Syndrome.
Additional gene information for TMEM245 Gene
- HGNC(1363)
- Entrez Gene(23731)
- Ensembl(ENSG00000106771)
- UniProtKB(Q9H330)
- Open Targets Platform(ENSG00000106771)
- Monarch Initiative
- Search for TMEM245 at DataMed
- Search for TMEM245 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM245 Gene
Genomics for TMEM245 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TMEM245 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TMEM245 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM245
Genomic Locations for TMEM245 Gene
Genomic Locations for TMEM245 Gene
- chr9:109,015,135-109,119,963
- (GRCh38/hg38)
- Size:
- 104,829 bases
- Orientation:
- Minus strand
- chr9:111,777,415-111,882,225
- (GRCh37/hg19)
- Size:
- 104,811 bases
- Orientation:
- Minus strand
Genomic View for TMEM245 Gene
Genes around TMEM245 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q31.3 by HGNC
- 9q31.3 by Entrez Gene
- 9q31.3 by Ensembl
TMEM245 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TMEM245 Gene
Proteins for TMEM245 Gene
-
Protein details for TMEM245 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H330-TM245_HUMAN
- Recommended name:
- Transmembrane protein 245
- Protein Accession:
- Q9H330
- B4DSW7
- Q5JTQ5
- Q5SS43
- Q6ZME3
- Q8NDJ5
- Q96CG6
Protein attributes for TMEM245 Gene
- Size:
- 879 amino acids
- Molecular mass:
- 97357 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAG43365.1; Type=Frameshift; Evidence={ECO:0000305};
- Miscellaneous:
-
- [Isoform 4]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Protein Expression for TMEM245 Gene
Post-translational modifications for TMEM245 Gene
Other Protein References for TMEM245 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-TMEM245 (aa 268-350) polyclonal antibody
- Novus Biologicals Antibodies for TMEM245
- Invitrogen Antibodies for TMEM245 (AFLGC-TMEM245)
- antibodies-online: Show 17 available TMEM245 Antibodies ranked by validation data
-
Biorbyt antibodies for TMEM245
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TMEM245
- Origene Custom Protein Services for TMEM245
- Novus Biologicals proteins for TMEM245
No data available for DME Specific Peptides for TMEM245 Gene
Domains & Families for TMEM245 Gene
Gene Families for TMEM245 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for TMEM245 Gene
- InterPro:
- Blocks:
-
- Protein of unknown function UPF0118
- ProtoNet:
Suggested Antigen Peptide Sequences for TMEM245 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein CG-2 (CI005_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9H330UniProtKB/Swiss-Prot:
TM245_HUMAN :- Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
- Family:
-
- Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
Function for TMEM245 Gene
Phenotypes From GWAS Catalog for TMEM245 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
Phenotypes for TMEM245 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for TMEM245
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TMEM245 - Select products 50% OFF >
- * TMEM245 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TMEM245
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TMEM245
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM245
miRNA for TMEM245 Gene
- miRTarBase miRNAs that target TMEM245
-
- mmu-miR-758-3p (MIRT007613)
- mmu-miR-301b-3p (MIRT007826)
- mmu-miR-7b-5p (MIRT009309)
- mmu-miR-15a-5p (MIRT011764)
- mmu-miR-19b-3p (MIRT012484)
- mmu-miR-30e-5p (MIRT013307)
- mmu-miR-181a-5p (MIRT014227)
- hsa-miR-374b-5p (MIRT016078)
- hsa-miR-340-5p (MIRT019650)
- hsa-miR-106b-5p (MIRT020473)
- hsa-miR-186-5p (MIRT021185)
- hsa-miR-221-3p (MIRT024168)
- hsa-miR-21-5p (MIRT030795)
- hsa-miR-16-5p (MIRT031582)
- hsa-miR-222-3p (MIRT046663)
- hsa-miR-183-5p (MIRT047061)
- hsa-miR-4662a-5p (MIRT106793)
- hsa-miR-3129-3p (MIRT106808)
- hsa-miR-5583-5p (MIRT106812)
- hsa-miR-93-3p (MIRT106826)
- hsa-miR-3692-5p (MIRT106831)
- hsa-miR-6507-5p (MIRT106832)
- hsa-miR-548a-3p (MIRT323904)
- hsa-miR-548e-3p (MIRT323905)
- hsa-miR-548f-3p (MIRT323906)
- hsa-miR-548ar-3p (MIRT323908)
- hsa-miR-5582-3p (MIRT323909)
- hsa-miR-548az-3p (MIRT323910)
- hsa-miR-374a-5p (MIRT441029)
- hsa-miR-20a-5p (MIRT441030)
- hsa-miR-526a (MIRT441768)
- hsa-miR-523-5p (MIRT441769)
- hsa-miR-522-5p (MIRT441770)
- hsa-miR-520c-5p (MIRT441771)
- hsa-miR-519c-5p (MIRT441772)
- hsa-miR-519b-5p (MIRT441773)
- hsa-miR-519a-5p (MIRT441774)
- hsa-miR-518f-5p (MIRT441775)
- hsa-miR-518e-5p (MIRT441776)
- hsa-miR-518d-5p (MIRT441777)
- hsa-miR-520g-5p (MIRT441778)
- hsa-miR-142-3p (MIRT492062)
- hsa-miR-4280 (MIRT492063)
- hsa-miR-562 (MIRT492064)
- hsa-miR-513c-3p (MIRT492065)
- hsa-miR-513a-3p (MIRT492066)
- hsa-miR-3606-3p (MIRT492067)
- hsa-miR-7844-5p (MIRT492068)
- hsa-miR-6864-3p (MIRT497397)
- hsa-miR-3672 (MIRT497398)
- hsa-miR-27b-5p (MIRT497399)
- hsa-miR-873-3p (MIRT497400)
- hsa-miR-376b-3p (MIRT505332)
- hsa-miR-376a-3p (MIRT505333)
- hsa-miR-3157-5p (MIRT505334)
- hsa-miR-95-3p (MIRT505335)
- hsa-miR-4524b-5p (MIRT505336)
- hsa-miR-4524a-5p (MIRT505337)
- hsa-miR-6801-5p (MIRT505338)
- hsa-miR-676-5p (MIRT505339)
- hsa-miR-103b (MIRT505340)
- hsa-miR-4691-3p (MIRT505341)
- hsa-miR-646 (MIRT505342)
- hsa-miR-503-5p (MIRT505343)
- hsa-miR-6838-5p (MIRT505344)
- hsa-miR-497-5p (MIRT505345)
- hsa-miR-424-5p (MIRT505346)
- hsa-miR-195-5p (MIRT505347)
- hsa-miR-15b-5p (MIRT505348)
- hsa-miR-15a-5p (MIRT505349)
- hsa-miR-205-3p (MIRT546287)
- hsa-miR-6513-5p (MIRT553505)
- hsa-miR-887-5p (MIRT553506)
- hsa-miR-3913-5p (MIRT553507)
- hsa-miR-3122 (MIRT553508)
- hsa-miR-450a-1-3p (MIRT553509)
- hsa-miR-5089-5p (MIRT553510)
- hsa-miR-6728-5p (MIRT553511)
- hsa-miR-769-3p (MIRT553512)
- hsa-miR-450b-3p (MIRT553513)
- hsa-miR-6844 (MIRT553514)
- hsa-miR-6071 (MIRT553515)
- hsa-miR-593-3p (MIRT553516)
- hsa-miR-193a-5p (MIRT553517)
- hsa-miR-5187-5p (MIRT553518)
- hsa-miR-5589-5p (MIRT553519)
- hsa-miR-4731-5p (MIRT553520)
- hsa-miR-187-5p (MIRT553521)
- hsa-miR-661 (MIRT553522)
- hsa-miR-4693-3p (MIRT553523)
- hsa-miR-9-5p (MIRT553524)
- hsa-miR-6728-3p (MIRT553525)
- hsa-miR-4686 (MIRT553526)
- hsa-miR-4712-3p (MIRT553527)
- hsa-miR-6512-5p (MIRT553528)
- mmu-miR-3065-5p (MIRT584023)
- mmu-miR-466e-5p (MIRT594996)
- mmu-miR-1187 (MIRT594997)
- mmu-miR-466a-5p (MIRT594998)
- mmu-miR-466p-5p (MIRT594999)
- mmu-miR-466d-5p (MIRT595000)
- mmu-miR-466k (MIRT595001)
- mmu-miR-466i-5p (MIRT595002)
- mmu-miR-466l-5p (MIRT595003)
- mmu-miR-3087-3p (MIRT599236)
- mmu-miR-3470b (MIRT599238)
- mmu-miR-1954 (MIRT599239)
- mmu-miR-871-3p (MIRT599240)
- mmu-miR-193a-3p (MIRT599241)
- mmu-miR-193b-3p (MIRT599242)
- mmu-miR-290a-5p (MIRT599243)
- mmu-miR-292a-5p (MIRT599244)
- mmu-miR-5125 (MIRT599245)
- mmu-miR-3110-5p (MIRT599246)
- mmu-miR-150-5p (MIRT599247)
- mmu-miR-5127 (MIRT599248)
- mmu-miR-105 (MIRT599249)
- mmu-miR-302b-3p (MIRT599250)
- mmu-miR-302d-3p (MIRT599251)
- mmu-miR-294-3p (MIRT599252)
- mmu-miR-291a-3p (MIRT599253)
- mmu-miR-295-3p (MIRT599254)
- mmu-miR-302a-3p (MIRT599255)
- mmu-miR-1186a (MIRT599256)
- hsa-miR-6793-3p (MIRT610406)
- hsa-miR-216b-3p (MIRT610407)
- hsa-miR-603 (MIRT610408)
- hsa-miR-8485 (MIRT610409)
- hsa-miR-4298 (MIRT618816)
- hsa-miR-1302 (MIRT618817)
- hsa-miR-3189-3p (MIRT618818)
- hsa-miR-212-5p (MIRT618819)
- hsa-miR-600 (MIRT630789)
- hsa-miR-502-5p (MIRT652412)
- hsa-miR-6798-3p (MIRT652413)
- hsa-miR-4640-3p (MIRT652414)
- hsa-miR-361-3p (MIRT665771)
- hsa-miR-519d-3p (MIRT728055)
- hsa-miR-93-5p (MIRT728056)
- hsa-miR-17-5p (MIRT728057)
- hsa-miR-20b-5p (MIRT728058)
- hsa-miR-1273f (MIRT783321)
- hsa-miR-129-5p (MIRT783617)
- hsa-miR-193b-5p (MIRT784053)
- hsa-miR-19a-5p (MIRT784092)
- hsa-miR-19b-1-5p (MIRT784105)
- hsa-miR-19b-2-5p (MIRT784118)
- hsa-miR-3170 (MIRT784733)
- hsa-miR-3665 (MIRT785098)
- hsa-miR-3674 (MIRT785182)
- hsa-miR-3680-3p (MIRT785224)
- hsa-miR-450b-5p (MIRT786067)
- hsa-miR-4732-5p (MIRT786564)
- hsa-miR-507 (MIRT787048)
- hsa-miR-557 (MIRT787657)
- hsa-miR-6511b-5p (MIRT788291)
- hsa-miR-6516-5p (MIRT788376)
- hsa-miR-657 (MIRT788393)
- hsa-miR-6811-5p (MIRT788889)
- hsa-miR-6832-5p (MIRT789008)
- hsa-miR-6855-5p (MIRT789093)
- hsa-miR-6890-5p (MIRT789352)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TMEM245
- Browse OriGene Inhibitory RNA Products For TMEM245
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM245
Clone Products
- Applied Biological Materials (abm): Clones for TMEM245 - Select products 50% OFF >
- * TMEM245 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TMEM245
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TMEM245
Cell Line Products
-
Horizon Cell Lines for TMEM245
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM245 Gene
Localization for TMEM245 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TMEM245 Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| cytosol | 2 |
| peroxisome | 0 |
- Cytosol (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,NAS | 10564813 |
Pathways & Interactions for TMEM245 Gene
Interacting Proteins for TMEM245 Gene
GPS-Prot Interaction Network for TMEM245
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
No data available for Pathways by source and SIGNOR curated interactions for TMEM245 Gene
Transcripts for TMEM245 Gene
mRNA/cDNA for TMEM245 Gene
- 2 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000374586 7999 nts (view in UCSC)
- ENST00000413712 1973 nts (view in UCSC)
- ENST00000472207 3261 nts (view in UCSC)
- ENST00000482868 555 nts (view in UCSC)
- ENST00000491854 2435 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TMEM245 - Select products 50% OFF >
- * TMEM245 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TMEM245
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TMEM245
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM245
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TMEM245
- Browse OriGene Inhibitory RNA Products For TMEM245
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM245
Clone Products
- Applied Biological Materials (abm): Clones for TMEM245 - Select products 50% OFF >
- * TMEM245 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TMEM245
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TMEM245
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: |
Relevant External Links for TMEM245 Gene
- GeneLoc Exon Structure for
- TMEM245
Expression for TMEM245 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Thyroid (Endocrine System)
-
Adrenal Gland (Endocrine System)
-
Ovary (Reproductive System)
This gene is overexpressed in Nasal epithelium (31.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM245 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM245
SOURCE GeneReport for Unigene cluster for TMEM245 Gene:
Hs.308074mRNA Expression by UniProt/SwissProt for TMEM245 Gene:
Q9H330-TM245_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for TMEM245 Gene
- Eye(4.4)
- Liver(4.3)
- Blood(4.1)
- Nervous system(3.8)
- Lung(3.6)
- Kidney(3.3)
- Pancreas(2.4)
Primer Products
-
OriGene qPCR primer pairs for TMEM245
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM245 Gene
Orthologs for TMEM245 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TMEM245 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TMEM245 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TMEM245 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tmem245 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TMEM245 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tmem245 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | TMEM245 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | C2H9ORF5 30 |
|
||
| TMEM245 31 |
|
OneToOne | |||
| Lizard (Anolis carolinensis) |
Reptilia | TMEM245 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tmem245 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tmem245 31 |
|
OneToMany | |
| LOC100000119 30 |
|
||||
| TMEM245 (2 of 2) 31 |
|
OneToMany | |||
| Dr.14788 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG2698 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003409 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | M01F1.4 30 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for TMEM245 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TMEM245 Gene
- ENSEMBL:
- Gene Tree for TMEM245 (if available)
- TreeFam:
- Gene Tree for TMEM245 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TMEM245: view image
Paralogs for TMEM245 Gene
No data available for Paralogs for TMEM245 Gene
Variants for TMEM245 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMEM245 Gene
| SNP ID | Clinical significance and condition | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 776439 | Benign: not provided | 109,087,295(-) | G/A | SYNONYMOUS_VARIANT | |
| rs12001627 | - | p.Asp9Glu | |||
| rs2271877 | - | p.Ala314Thr | |||
| rs3750455 | - | p.Thr787Ala |
Residual Variation Intolerance Score:
16.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
9.89;
89.74% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TMEM245 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TMEM245
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM245 Gene
Disorders for TMEM245 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neuropathy, hereditary sensory and autonomic, type iii |
|
|
| hypermobility syndrome |
|
|
Search TMEM245 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TMEM245
No data available for UniProtKB/Swiss-Prot and Genatlas for TMEM245 Gene
Publications for TMEM245 Gene
- Cloning, genomic organization and expression of a putative human transmembrane protein related to the Caenorhabditis elegans M01F1.4 gene. (PMID: 10564813) Chadwick BP … Slaugenhaupt SA (Gene 1999) 2 3 4
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
ExternalLinks
Products for TMEM245 Gene
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Sources for TMEM245 Gene
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