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Aliases for TMEM233 Gene
Aliases for TMEM233 Gene
External Ids for TMEM233 Gene
- HGNC: 37219
- Entrez Gene: 387890
- Ensembl: ENSG00000224982
- OMIM: 618296
- UniProtKB: B4DJY2
Previous GeneCards Identifiers for TMEM233 Gene
- GC12P118516
- GC12P120031
- GC12P117039
Summaries for TMEM233 Gene
GeneCards Summary for TMEM233 Gene
TMEM233 (Transmembrane Protein 233) is a Protein Coding gene. An important paralog of this gene is TRARG1.
Additional gene information for TMEM233 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM233 Gene
Genomics for TMEM233 Gene
GeneHancer (GH) Regulatory Elements for TMEM233 Gene
Promoters and enhancers for TMEM233 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TMEM233 on UCSC Golden Path with GeneCards custom track
Genomic Locations for TMEM233 Gene
Genomic Locations for TMEM233 Gene
- chr12:119,592,636-119,654,442
- (GRCh38/hg38)
- Size:
- 61,807 bases
- Orientation:
- Plus strand
- chr12:120,031,264-120,079,363
- (GRCh37/hg19)
- Size:
- 48,100 bases
- Orientation:
- Plus strand
Genomic View for TMEM233 Gene
Genes around TMEM233 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.23 by HGNC
- 12q24.23 by Entrez Gene
- 12q24.23 by Ensembl
TMEM233 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TMEM233 Gene
Proteins for TMEM233 Gene
-
Protein details for TMEM233 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- B4DJY2-TM233_HUMAN
- Recommended name:
- Transmembrane protein 233
- Protein Accession:
- B4DJY2
Protein attributes for TMEM233 Gene
- Size:
- 109 amino acids
- Molecular mass:
- 12074 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for TMEM233 Gene
Other Protein References for TMEM233 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- antibodies-online: Show 11 available TMEM233 Antibodies ranked by validation data
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TMEM233
- Origene Custom Protein Services for TMEM233
No data available for DME Specific Peptides for TMEM233 Gene
Domains & Families for TMEM233 Gene
Gene Families for TMEM233 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for TMEM233 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for TMEM233 Gene
- GenScript: Design optimal peptide antigens:
-
- Interferon-induced transmembrane domain-containing protein D2 (TM233_HUMAN)
Graphical View of Domain Structure for InterPro Entry
B4DJY2- Family:
-
- Belongs to the CD225/Dispanin family.
Function for TMEM233 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for TMEM233
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TMEM233
- genomics-online: gRNA clones - Search results for available TMEM233 gene related products
- Applied Biological Materials (abm): CRISPR Clones for TMEM233 - Select products 50% OFF >
- * TMEM233 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * TMEM233 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM233
miRNA for TMEM233 Gene
- miRTarBase miRNAs that target TMEM233
-
- hsa-mir-6867-3p (MIRT494969)
- hsa-mir-629-3p (MIRT494970)
- hsa-mir-4713-5p (MIRT494971)
- hsa-mir-4258 (MIRT494972)
- hsa-mir-374c-3p (MIRT494973)
- hsa-mir-5571-5p (MIRT494974)
- hsa-mir-1976 (MIRT621793)
- hsa-mir-3653-5p (MIRT621794)
- hsa-mir-6747-3p (MIRT621795)
- hsa-mir-6727-3p (MIRT621796)
- hsa-mir-4722-3p (MIRT621797)
- hsa-mir-6769b-3p (MIRT621798)
- hsa-mir-4723-3p (MIRT621799)
- hsa-mir-3183 (MIRT621800)
- hsa-mir-6885-3p (MIRT635116)
- hsa-mir-129-5p (MIRT635117)
- hsa-mir-2115-3p (MIRT635118)
- hsa-mir-449c-3p (MIRT635119)
- hsa-mir-296-3p (MIRT635120)
- hsa-mir-1206 (MIRT783127)
- hsa-mir-4776-3p (MIRT786737)
- hsa-mir-5009-5p (MIRT786971)
- hsa-mir-5696 (MIRT787808)
- hsa-mir-578 (MIRT787909)
- hsa-mir-579-3p (MIRT787918)
- hsa-mir-664b-3p (MIRT788439)
- hsa-mir-6853-3p (MIRT789085)
- hsa-mir-8058 (MIRT789769)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TMEM233
- Browse OriGene Inhibitory RNA Products For TMEM233
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM233
- genomics-online: shRNA clones - Search results for available TMEM233 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TMEM233
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TMEM233
- genomics-online: cdna clones - Search results for available TMEM233 gene related products
- orf clones - Search results for available TMEM233 gene related products
- Applied Biological Materials (abm): Clones for TMEM233 - Select products 50% OFF >
- * TMEM233 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * TMEM233 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for TMEM233
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM233 Gene
Localization for TMEM233 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TMEM233 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IBA | 21873635 |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM233 Gene
Transcripts for TMEM233 Gene
mRNA/cDNA for TMEM233 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (22) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000426426 2775 bps (ENST00000426426.2)
- ENST00000453450 438 bps (ENST00000453450.2)
CRISPR Products
-
OriGene CRISPR knockouts for TMEM233
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TMEM233
- genomics-online: gRNA clones - Search results for available TMEM233 gene related products
- Applied Biological Materials (abm): CRISPR Clones for TMEM233 - Select products 50% OFF >
- * TMEM233 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * TMEM233 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM233
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TMEM233
- Browse OriGene Inhibitory RNA Products For TMEM233
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM233
- genomics-online: shRNA clones - Search results for available TMEM233 gene related products
Clone Products
- Sino Biological Human cDNA Clone for TMEM233
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TMEM233
- genomics-online: cdna clones - Search results for available TMEM233 gene related products
- orf clones - Search results for available TMEM233 gene related products
- Applied Biological Materials (abm): Clones for TMEM233 - Select products 50% OFF >
- * TMEM233 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * TMEM233 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for TMEM233 Gene
mRNA differential expression in normal tissues according to GTEx for TMEM233 Gene
This gene is overexpressed in Muscle - Skeletal (x37.6).
NURSA nuclear receptor signaling pathways regulating expression of TMEM233 Gene:
TMEM233SOURCE GeneReport for Unigene cluster for TMEM233 Gene:
Hs.530965Evidence on tissue expression from TISSUES for TMEM233 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for TMEM233
- genomics-online: primer clones - Search results for available TMEM233 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM233 Gene
Orthologs for TMEM233 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TMEM233 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | TMEM233 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | TMEM233 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Tmem233 17 33 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TMEM233 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 33 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | TMEM233 32 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TMEM233 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tmem233 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC101885033 32 |
|
||
| BX005328.1 33 |
|
OneToOne |
- Species where no ortholog for TMEM233 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for TMEM233 Gene
- ENSEMBL:
- Gene Tree for TMEM233 (if available)
- TreeFam:
- Gene Tree for TMEM233 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TMEM233: view image
Paralogs for TMEM233 Gene
Variants for TMEM233 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000174550 | -- | 119,610,595(+) | G/C | intron_variant | |
| rs1000178563 | -- | 119,636,904(+) | A/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000180431 | -- | 119,610,257(+) | T/C | intron_variant | |
| rs1000205886 | -- | 119,594,070(+) | G/A | intron_variant | |
| rs1000208897 | -- | 119,654,764(+) | A/G | downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3630908 | CNV | gain | 21293372 |
| esv3630909 | CNV | gain | 21293372 |
| esv3630910 | CNV | loss | 21293372 |
| nsv832529 | CNV | loss | 17160897 |
Gene Damage Index Score:
0.61;
13.02% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TMEM233 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TMEM233
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM233 Gene
Disorders for TMEM233 Gene
Additional Disease Information for TMEM233
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for TMEM233 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM233 Gene
Publications for TMEM233 Gene
- The dispanins: a novel gene family of ancient origin that contains 14 human members. (PMID: 22363774) Sällman Almén M … Schiöth HB (PloS one 2012) 3 4 56
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 43 56
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 56
- Benefits of random-priming: exhaustive survey of a cDNA library from lung tissue of a SARS patient. (PMID: 21328370) Wu H … Wang X (Journal of medical virology 2011) 3 56
- Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. (PMID: 20622878) Remmers EF … Gül A (Nature genetics 2010) 43 56
ExternalLinks
Products for TMEM233 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TMEM233
- Origene Custom Protein Services for TMEM233
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TMEM233
- Browse OriGene Inhibitory RNA Products For TMEM233
- OriGene qPCR primer pairs for TMEM233
- OriGene CRISPR knockouts for TMEM233
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TMEM233
- Sino Biological Human cDNA Clone for TMEM233
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- antibodies-online: Show 11 available TMEM233 Antibodies ranked by validation data
- antibodies-online: Search results for available TMEM233 related products ranked by validation data
- antibodies-online: Search results for available TMEM233 related products ranked by validation data
- Horizon Cell Lines for TMEM233
- genomics-online: cdna clones - Search results for available TMEM233 gene related products
- orf clones - Search results for available TMEM233 gene related products
- genomics-online: gRNA clones - Search results for available TMEM233 gene related products
- genomics-online: primer clones - Search results for available TMEM233 gene related products
- genomics-online: shRNA clones - Search results for available TMEM233 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TMEM233
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TMEM233
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TMEM233
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM233
Sources for TMEM233 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource