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TMEM219 (Transmembrane Protein 219) is a Protein Coding gene. Diseases associated with TMEM219 include Hermansky-Pudlak Syndrome and Schizophrenia 3. Among its related pathways are TP53 Regulates Transcription of Cell Death Genes and Gene Expression. An important paralog of this gene is TMEM248.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 20353938 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Gene Expression |
.48
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2 | TP53 Regulates Transcription of Cell Death Genes | ||
3 | Regulation of TP53 Activity |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006915 | apoptotic process | IEA | -- |
GO:0042981 | regulation of apoptotic process | TAS | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||
SP2: | |||||||||||||||||||||||
SP3: | - | - | - | ||||||||||||||||||||
SP4: | |||||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TMEM219 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | TMEM219 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | TMEM219 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Tmem219 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Tmem219 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | TMEM219 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | TMEM219 31 |
|
OneToOne |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv29470 | CNV | loss | 19812545 |
esv3638377 | CNV | loss | 21293372 |
Disorder | Aliases | PubMed IDs |
---|---|---|
hermansky-pudlak syndrome |
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|
schizophrenia 3 |
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