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Aliases for TMEM210 Gene

Aliases for TMEM210 Gene

  • Transmembrane Protein 210 2 3 5

External Ids for TMEM210 Gene

Previous GeneCards Identifiers for TMEM210 Gene

  • GC09U901043
  • GC09M139186
  • GC09M140065

Summaries for TMEM210 Gene

GeneCards Summary for TMEM210 Gene

TMEM210 (Transmembrane Protein 210) is a Protein Coding gene.

Additional gene information for TMEM210 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM210 Gene

Genomics for TMEM210 Gene

GeneHancer (GH) Regulatory Elements for TMEM210 Gene

Promoters and enhancers for TMEM210 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I137166 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 +1.3 1264 10.1 HDGF SIN3A ZNF2 ZBTB7B GLIS2 ZNF143 KLF7 SP3 REST GMEB1 ENSG00000261793 MIR3621 LRRC26 TMEM210 MAN1B1 TPRN DPH7 INPP5E ARRDC1-AS1 EXD3
GH09I137149 Enhancer 1 Ensembl ENCODE 13 +21.5 21535 1.9 HDGF DEAF1 KLF5 BRCA1 ZEB1 ZNF335 E2F8 KLF7 IKZF2 RUNX3 NDOR1 ANAPC2 EHMT1 SEC16A TMEM210 SDCCAG3 TPRN DPP7 MAN1B1 TMEM203
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TMEM210 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TMEM210 Gene

Genomic Locations for TMEM210 Gene
chr9:137,170,858-137,172,409
(GRCh38/hg38)
Size:
1,552 bases
Orientation:
Minus strand
chr9:140,065,310-140,066,861
(GRCh37/hg19)

Genomic View for TMEM210 Gene

Genes around TMEM210 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM210 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM210 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM210 Gene

Proteins for TMEM210 Gene

  • Protein details for TMEM210 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NLX4-TM210_HUMAN
    Recommended name:
    Transmembrane protein 210
    Protein Accession:
    A6NLX4

    Protein attributes for TMEM210 Gene

    Size:
    147 amino acids
    Molecular mass:
    15516 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM210 Gene

Post-translational modifications for TMEM210 Gene

No Post-translational modifications

Other Protein References for TMEM210 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM210 Gene

Domains & Families for TMEM210 Gene

Gene Families for TMEM210 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM210 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM210 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM210: view

No data available for UniProtKB/Swiss-Prot for TMEM210 Gene

Function for TMEM210 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM210 Gene

Localization for TMEM210 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM210 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM210 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM210: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMEM210 Gene

Pathways & Interactions for TMEM210 Gene

SuperPathways for TMEM210 Gene

No Data Available

Interacting Proteins for TMEM210 Gene

Gene Ontology (GO) - Biological Process for TMEM210 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM210 Gene

Drugs & Compounds for TMEM210 Gene

No Compound Related Data Available

Transcripts for TMEM210 Gene

mRNA/cDNA for TMEM210 Gene

(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM210 Gene

No ASD Table

Relevant External Links for TMEM210 Gene

GeneLoc Exon Structure for
TMEM210
ECgene alternative splicing isoforms for
TMEM210

Expression for TMEM210 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM210 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM210 Gene

This gene is overexpressed in Testis (x49.6).

NURSA nuclear receptor signaling pathways regulating expression of TMEM210 Gene:

TMEM210
genes like me logo Genes that share expression patterns with TMEM210: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM210 Gene

Orthologs for TMEM210 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM210 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM210 33
  • 95.69 (n)
dog
(Canis familiaris)
Mammalia TMEM210 33 34
  • 81.86 (n)
rat
(Rattus norvegicus)
Mammalia Tmem210 33
  • 81.73 (n)
cow
(Bos Taurus)
Mammalia TMEM210 33 34
  • 81.06 (n)
mouse
(Mus musculus)
Mammalia Tmem210 33 16 34
  • 80.62 (n)
Species where no ortholog for TMEM210 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM210 Gene

ENSEMBL:
Gene Tree for TMEM210 (if available)
TreeFam:
Gene Tree for TMEM210 (if available)

Paralogs for TMEM210 Gene

No data available for Paralogs for TMEM210 Gene

Variants for TMEM210 Gene

Sequence variations from dbSNP and Humsavar for TMEM210 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000093890 -- 137,171,173(-) C/A/G/T intron_variant
rs1000146335 -- 137,170,959(-) A/G 3_prime_UTR_variant
rs1001159501 -- 137,171,962(-) G/A coding_sequence_variant, synonymous_variant
rs1001720589 -- 137,173,920(-) CAGGCGCAGCTCACAG/CAG upstream_transcript_variant
rs1002489842 -- 137,173,114(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM210 Gene

Variant ID Type Subtype PubMed ID
nsv951207 CNV deletion 24416366
nsv616007 CNV loss 21841781
nsv616005 CNV loss 21841781
nsv524322 CNV loss 19592680
nsv469918 CNV loss 18288195
nsv1161918 CNV duplication 26073780
esv3622023 CNV gain 21293372
esv2761561 CNV gain 21179565
esv2422220 CNV deletion 17116639
dgv13007n54 CNV loss 21841781

Variation tolerance for TMEM210 Gene

Gene Damage Index Score: 1.47; 28.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM210 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM210

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM210 Gene

Disorders for TMEM210 Gene

Additional Disease Information for TMEM210

No disorders were found for TMEM210 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM210 Gene

Publications for TMEM210 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58

Products for TMEM210 Gene

Sources for TMEM210 Gene

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