Aliases for TMEM201 Gene
External Ids for TMEM201 Gene
Previous GeneCards Identifiers for TMEM201 Gene
GeneCards Summary for TMEM201 Gene
TMEM201 (Transmembrane Protein 201) is a Protein Coding gene. Diseases associated with TMEM201 include Ileitis and Gastroduodenitis. Gene Ontology (GO) annotations related to this gene include actin filament binding and lamin binding.
UniProtKB/Swiss-Prot Summary for TMEM201 Gene
Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery (PubMed:27541860).
[Isoform 2]: May define a distinct membrane domain in the vicinity of the mitotic spindle (PubMed:19494128). Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina (PubMed:21610090).