TMEM191C Gene (Protein Coding)

Transmembrane Protein 191C

GC22P024210
GIFtS:
21
See more...

Aliases for TMEM191C Gene

Aliases for TMEM191C Gene

  • Transmembrane Protein 191C 2 3 4 5
  • KB-1323B2.6 3
  • TMEM191C 5

External Ids for TMEM191C Gene

Previous GeneCards Identifiers for TMEM191C Gene

  • GC22P020151
  • GC22P021821
  • GC22P021825
  • GC22P021469
  • GC22P021500
  • GC22P022105
  • GC22P022145
  • GC22P022181
  • GC22P023725
  • GC22P021542
  • GC22P021843
  • GC22P021870
  • GC22P021906
  • GC22P021942
  • GC22P021972
  • GC22P022014
  • GC22P022063

Summaries for TMEM191C Gene

GeneCards Summary for TMEM191C Gene

TMEM191C (Transmembrane Protein 191C) is a Protein Coding gene. An important paralog of this gene is TMEM191B.

Additional gene information for TMEM191C Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM191C Gene

Genomics for TMEM191C Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for TMEM191C Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM191C on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM191C

Top Transcription factor binding sites by QIAGEN in the TMEM191C gene promoter:
  • aMEF-2
  • AREB6
  • E47
  • FOXL1
  • HEN1
  • MEF-2A
  • Pax-5
  • POU2F1
  • POU2F1a
  • Tal-1

Genomic Locations for TMEM191C Gene

Genomic Locations for TMEM191C Gene
chr22:21,466,423-21,471,269
(GRCh38/hg38)
Size:
4,847 bases
Orientation:
Plus strand
chr22:21,820,712-21,825,558
(GRCh37/hg19)
Size:
4,847 bases
Orientation:
Plus strand

Genomic View for TMEM191C Gene

Genes around TMEM191C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM191C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM191C Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TMEM191C Gene

Proteins for TMEM191C Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TMEM191C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGB0-T191C_HUMAN
    Recommended name:
    Transmembrane protein 191C
    Protein Accession:
    A6NGB0

    Protein attributes for TMEM191C Gene

    Size:
    347 amino acids
    Molecular mass:
    39292 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM191C Gene

Protein Expression for TMEM191C Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for TMEM191C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM191C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM191C Gene

Domains & Families for TMEM191C Gene

Gene Families for TMEM191C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for TMEM191C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM191C Gene

GenScript: Design optimal peptide antigens:
  • Transmembrane protein 191C (T191C_HUMAN)

Graphical View of Domain Structure for InterPro Entry

A6NGB0

UniProtKB/Swiss-Prot:

T191C_HUMAN :
  • Belongs to the TMEM191 family.
Family:
  • Belongs to the TMEM191 family.
genes like me logo Genes that share domains with TMEM191C: view

Function for TMEM191C Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM191C

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM191C Gene

Localization for TMEM191C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM191C Gene

Membrane. Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM191C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM191C: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMEM191C Gene

Pathways & Interactions for TMEM191C Gene

PathCards logo

SuperPathways for TMEM191C Gene

No Data Available

Interacting Proteins for TMEM191C Gene

Gene Ontology (GO) - Biological Process for TMEM191C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM191C Gene

Drugs & Compounds for TMEM191C Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TMEM191C Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TMEM191C Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
14 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM191C

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM191C Gene

No ASD Table

Relevant External Links for TMEM191C Gene

GeneLoc Exon Structure for
TMEM191C

Expression for TMEM191C Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMEM191C Gene

mRNA expression in normal human tissues for TMEM191C Gene
mRNA expression by GTEx for TMEM191C Gene

mRNA differential expression in normal tissues according to GTEx for TMEM191C Gene

This gene is overexpressed in Testis (x11.7).

Protein differential expression in normal tissues from HIPED for TMEM191C Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM191C Gene



Protein tissue co-expression partners for TMEM191C Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM191C

SOURCE GeneReport for Unigene cluster for TMEM191C Gene:

Hs.376511
genes like me logo Genes that share expression patterns with TMEM191C: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM191C Gene

Orthologs for TMEM191C Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM191C Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia TMEM191C 30
  • 96.83 (n)
Species where no ortholog for TMEM191C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TMEM191C Gene

ENSEMBL:
Gene Tree for TMEM191C (if available)
TreeFam:
Gene Tree for TMEM191C (if available)

Paralogs for TMEM191C Gene

Paralogs for TMEM191C Gene

genes like me logo Genes that share paralogs with TMEM191C: view

Variants for TMEM191C Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for TMEM191C Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM191C Gene

Variant ID Type Subtype PubMed ID
dgv4486n100 CNV gain 25217958
dgv4487n100 CNV gain 25217958
dgv4488n100 CNV gain 25217958
dgv4489n100 CNV gain 25217958
dgv4490n100 CNV gain 25217958
dgv4491n100 CNV gain 25217958
esv25508 CNV gain+loss 19812545
esv2678291 CNV deletion 23128226
esv2760719 CNV gain 21179565
esv2763699 CNV gain+loss 21179565
esv3584494 CNV gain 24956385
esv3893444 CNV gain 25118596
nsv1066391 CNV gain 25217958
nsv1073155 CNV deletion 25765185
nsv1118947 CNV deletion 24896259
nsv1160729 CNV duplication 26073780
nsv1160730 CNV deletion 26073780
nsv428386 CNV loss 18775914
nsv436864 CNV insertion 17901297
nsv442791 CNV gain 18776908
nsv469545 CNV gain 16826518
nsv471596 CNV gain+loss 15918152
nsv511071 OTHER inversion 20534489
nsv7350 OTHER inversion 18451855
nsv834145 CNV loss 17160897
nsv953042 CNV deletion 24416366

Additional Variant Information for TMEM191C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM191C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for TMEM191C Gene

Disorders for TMEM191C Gene

Additional Disease Information for TMEM191C

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for TMEM191C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM191C Gene

Publications for TMEM191C Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 4

ExternalLinks

View latest publications for TMEM191C gene in Mastermind

Products for TMEM191C Gene

Sources for TMEM191C Gene