Aliases for TMEM181 Gene
External Ids for TMEM181 Gene
Previous HGNC Symbols for TMEM181 Gene
Previous GeneCards Identifiers for TMEM181 Gene
The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]
GeneCards Summary for TMEM181 Gene
TMEM181 (Transmembrane Protein 181) is a Protein Coding gene. Diseases associated with TMEM181 include Chancroid and Isolated Growth Hormone Deficiency, Type Ib. Gene Ontology (GO) annotations related to this gene include toxic substance binding.
UniProtKB/Swiss-Prot Summary for TMEM181 Gene
Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication.