Aliases for TMEM160 Gene

Aliases for TMEM160 Gene

  • Transmembrane Protein 160 2 3 4 5
  • FLJ20512 2
  • TMEM160 5

External Ids for TMEM160 Gene

Previous GeneCards Identifiers for TMEM160 Gene

  • GC19M052242
  • GC19M047549
  • GC19M043973

Summaries for TMEM160 Gene

GeneCards Summary for TMEM160 Gene

TMEM160 (Transmembrane Protein 160) is a Protein Coding gene.

Additional gene information for TMEM160 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM160 Gene

Genomics for TMEM160 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TMEM160 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM160 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM160

Top Transcription factor binding sites by QIAGEN in the TMEM160 gene promoter:
  • AP-2gamma
  • Arnt
  • c-Ets-1
  • MIF-1
  • Roaz
  • USF-1
  • USF1
  • XBP-1
  • ZID

Genomic Locations for TMEM160 Gene

Genomic Locations for TMEM160 Gene
chr19:47,045,909-47,048,624
(GRCh38/hg38)
Size:
2,716 bases
Orientation:
Minus strand
chr19:47,549,165-47,551,888
(GRCh37/hg19)
Size:
2,724 bases
Orientation:
Minus strand

Genomic View for TMEM160 Gene

Genes around TMEM160 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM160 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM160 Gene

Proteins for TMEM160 Gene

  • Protein details for TMEM160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX00-TM160_HUMAN
    Recommended name:
    Transmembrane protein 160
    Protein Accession:
    Q9NX00
    Secondary Accessions:
    • Q9BU41

    Protein attributes for TMEM160 Gene

    Size:
    188 amino acids
    Molecular mass:
    19658 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM160 Gene

Post-translational modifications for TMEM160 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM160 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM160 Gene

Domains & Families for TMEM160 Gene

Gene Families for TMEM160 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM160 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM160 Gene

GenScript: Design optimal peptide antigens:
  • Transmembrane protein 160 (TM160_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NX00

UniProtKB/Swiss-Prot:

TM160_HUMAN :
  • Belongs to the TMEM160 family.
Family:
  • Belongs to the TMEM160 family.
genes like me logo Genes that share domains with TMEM160: view

Function for TMEM160 Gene

Phenotypes From GWAS Catalog for TMEM160 Gene

genes like me logo Genes that share phenotypes with TMEM160: view

Animal Model Products

CRISPR Products

miRNA for TMEM160 Gene

miRTarBase miRNAs that target TMEM160

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM160

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM160 Gene

Localization for TMEM160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM160 Gene

Membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM160 gene
Compartment Confidence
mitochondrion 2
peroxisome 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM160: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM160 Gene

Pathways & Interactions for TMEM160 Gene

PathCards logo

SuperPathways for TMEM160 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM160 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM160 Gene

Drugs & Compounds for TMEM160 Gene

No Compound Related Data Available

Transcripts for TMEM160 Gene

mRNA/cDNA for TMEM160 Gene

1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM160

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM160 Gene

No ASD Table

Relevant External Links for TMEM160 Gene

GeneLoc Exon Structure for
TMEM160

Expression for TMEM160 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TMEM160 Gene

Protein differential expression in normal tissues from HIPED for TMEM160 Gene

This gene is overexpressed in Nasal epithelium (64.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TMEM160 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM160

SOURCE GeneReport for Unigene cluster for TMEM160 Gene:

Hs.105606

Evidence on tissue expression from TISSUES for TMEM160 Gene

  • Lung(4.1)
genes like me logo Genes that share expression patterns with TMEM160: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM160 Gene

Orthologs for TMEM160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM160 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia TMEM160 30 31
  • 99.29 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia TMEM160 30 31
  • 89.18 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia TMEM160 30 31
  • 88.3 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Tmem160 30
  • 85.11 (n)
Mouse
(Mus musculus)
Mammalia Tmem160 30 17 31
  • 84.4 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia TMEM160 31
  • 68 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii tmem160 30 31
  • 58.52 (n)
OneToOne
Dr.17783 30
Species where no ortholog for TMEM160 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for TMEM160 Gene

ENSEMBL:
Gene Tree for TMEM160 (if available)
TreeFam:
Gene Tree for TMEM160 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TMEM160: view image

Paralogs for TMEM160 Gene

Pseudogenes.org Pseudogenes for TMEM160 Gene

genes like me logo Genes that share paralogs with TMEM160: view

No data available for Paralogs for TMEM160 Gene

Variants for TMEM160 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMEM160 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs11083857 - p.Gly120Ser

Additional dbSNP identifiers (rs#s) for TMEM160 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM160 Gene

Variant ID Type Subtype PubMed ID
nsv2512 CNV insertion 18451855

Variation tolerance for TMEM160 Gene

Gene Damage Index Score: 4.05; 60.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM160 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM160

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM160 Gene

Disorders for TMEM160 Gene

No disorders were found for TMEM160 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM160 Gene

Publications for TMEM160 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3
  4. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  5. E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. (PMID: 29676528) Khanna R … Parnaik VK (The FEBS journal 2018) 3

Products for TMEM160 Gene

  • Signalway ELISA kits for TMEM160

Sources for TMEM160 Gene