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Aliases for TMEM160 Gene

Aliases for TMEM160 Gene

  • Transmembrane Protein 160 2 3 5

External Ids for TMEM160 Gene

Previous GeneCards Identifiers for TMEM160 Gene

  • GC19M052242
  • GC19M047549
  • GC19M043973

Summaries for TMEM160 Gene

GeneCards Summary for TMEM160 Gene

TMEM160 (Transmembrane Protein 160) is a Protein Coding gene.

Additional gene information for TMEM160 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM160 Gene

Genomics for TMEM160 Gene

GeneHancer (GH) Regulatory Elements for TMEM160 Gene

Promoters and enhancers for TMEM160 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I047047 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 550.8 +0.2 182 2.5 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 TMEM160 ZC3H4 CCDC9 SLC1A5 NOP53-AS1 PNMA8A PIR57310
GH19I047105 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.4 -61.5 -61513 9.2 CLOCK MLX FEZF1 DMAP1 YBX1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZC3H4 ENSG00000268810 BICRA C5AR2 PRKD2 CCDC9 NOP53-AS1 SNORD23 ENSG00000268746 DHX34
GH19I047093 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.9 -48.2 -48211 7.6 HDGF PKNOX1 CLOCK FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 TMEM160 SAE1 PNMA8A GC19P047078 ZC3H4
GH19I046859 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.8 +185.4 185350 8.5 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC CCDC9 CCDC61 ZC3H4 BICRA ARHGAP35 SLC1A5 ENSG00000269124 TMEM160 ENSG00000268810 PPP5C
GH19I046983 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +63.7 63678 2.5 PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 RXRA ARHGAP35 TMEM160 AP2S1 FKRP STRN4 ZC3H4 C5AR1 DHX34 CCDC9 GC19P046965
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TMEM160 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TMEM160 gene promoter:

Genomic Locations for TMEM160 Gene

Genomic Locations for TMEM160 Gene
chr19:47,045,907-47,048,784
(GRCh38/hg38)
Size:
2,878 bases
Orientation:
Minus strand
chr19:47,549,165-47,551,888
(GRCh37/hg19)

Genomic View for TMEM160 Gene

Genes around TMEM160 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM160 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM160 Gene

Proteins for TMEM160 Gene

  • Protein details for TMEM160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX00-TM160_HUMAN
    Recommended name:
    Transmembrane protein 160
    Protein Accession:
    Q9NX00
    Secondary Accessions:
    • Q9BU41

    Protein attributes for TMEM160 Gene

    Size:
    188 amino acids
    Molecular mass:
    19658 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM160 Gene

Post-translational modifications for TMEM160 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM160 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM160 Gene

Domains & Families for TMEM160 Gene

Gene Families for TMEM160 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for TMEM160 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM160 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NX00

UniProtKB/Swiss-Prot:

TM160_HUMAN :
  • Belongs to the TMEM160 family.
Family:
  • Belongs to the TMEM160 family.
genes like me logo Genes that share domains with TMEM160: view

Function for TMEM160 Gene

Phenotypes From GWAS Catalog for TMEM160 Gene

genes like me logo Genes that share phenotypes with TMEM160: view

Animal Model Products

miRNA for TMEM160 Gene

miRTarBase miRNAs that target TMEM160

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM160 Gene

Localization for TMEM160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM160 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM160 gene
Compartment Confidence
mitochondrion 3
peroxisome 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM160: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM160 Gene

Pathways & Interactions for TMEM160 Gene

SuperPathways for TMEM160 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM160 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM160 Gene

Drugs & Compounds for TMEM160 Gene

No Compound Related Data Available

Transcripts for TMEM160 Gene

mRNA/cDNA for TMEM160 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(75) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM160 Gene

Transmembrane protein 160:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM160 Gene

No ASD Table

Relevant External Links for TMEM160 Gene

GeneLoc Exon Structure for
TMEM160
ECgene alternative splicing isoforms for
TMEM160

Expression for TMEM160 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM160 Gene

Protein differential expression in normal tissues from HIPED for TMEM160 Gene

This gene is overexpressed in Nasal epithelium (64.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TMEM160 Gene



Protein tissue co-expression partners for TMEM160 Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM160 Gene:

TMEM160

SOURCE GeneReport for Unigene cluster for TMEM160 Gene:

Hs.105606

Evidence on tissue expression from TISSUES for TMEM160 Gene

  • Lung(4.1)
genes like me logo Genes that share expression patterns with TMEM160: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM160 Gene

Orthologs for TMEM160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM160 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM160 33 34
  • 99.29 (n)
dog
(Canis familiaris)
Mammalia TMEM160 33 34
  • 89.18 (n)
cow
(Bos Taurus)
Mammalia TMEM160 33 34
  • 88.3 (n)
rat
(Rattus norvegicus)
Mammalia Tmem160 33
  • 85.11 (n)
mouse
(Mus musculus)
Mammalia Tmem160 33 16 34
  • 84.4 (n)
oppossum
(Monodelphis domestica)
Mammalia TMEM160 34
  • 68 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii tmem160 33 34
  • 58.52 (n)
Dr.17783 33
Species where no ortholog for TMEM160 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM160 Gene

ENSEMBL:
Gene Tree for TMEM160 (if available)
TreeFam:
Gene Tree for TMEM160 (if available)

Paralogs for TMEM160 Gene

Pseudogenes.org Pseudogenes for TMEM160 Gene

genes like me logo Genes that share paralogs with TMEM160: view

No data available for Paralogs for TMEM160 Gene

Variants for TMEM160 Gene

Sequence variations from dbSNP and Humsavar for TMEM160 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000184865 -- 47,047,148(-) T/G intron_variant
rs1000700398 -- 47,049,447(-) C/T upstream_transcript_variant
rs1000767991 -- 47,048,475(-) G/A/T coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, upstream_transcript_variant
rs1000980952 -- 47,048,125(-) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1001112783 -- 47,049,726(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM160 Gene

Variant ID Type Subtype PubMed ID
nsv2512 CNV insertion 18451855

Variation tolerance for TMEM160 Gene

Gene Damage Index Score: 4.05; 60.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM160 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM160

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM160 Gene

Disorders for TMEM160 Gene

Additional Disease Information for TMEM160

No disorders were found for TMEM160 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM160 Gene

Publications for TMEM160 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. (PMID: 27880917) St-Denis N … Gingras AC (Cell reports 2016) 3 58

Products for TMEM160 Gene

Sources for TMEM160 Gene

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