Aliases for TMEM14EP Gene

Aliases for TMEM14EP Gene

  • Transmembrane Protein 14E, Pseudogene 2 3 5
  • TMEM14E 3 4
  • Transmembrane Protein 14EP 4
  • Transmembrane Protein 14E 2

External Ids for TMEM14EP Gene

Previous HGNC Symbols for TMEM14EP Gene

  • TMEM14E

Summaries for TMEM14EP Gene

GeneCards Summary for TMEM14EP Gene

TMEM14EP (Transmembrane Protein 14E, Pseudogene) is a Pseudogene.

Additional gene information for TMEM14EP Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM14EP Gene

Genomics for TMEM14EP Gene

GeneHancer (GH) Regulatory Elements for TMEM14EP Gene

Promoters and enhancers for TMEM14EP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J152341 Enhancer 0.3 Ensembl 500.7 -1.1 -1111 0.6 REST POLR2A TMEM14EP MBNL1 NONHSAG036414.2
GH03J152339 Enhancer 0.3 Ensembl 500.7 +1.8 1789 1.2 HDGF TMEM14EP lnc-IGSF10-8 MBNL1
GH03J152297 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE dbSUPER 19.3 +40.2 40199 5.9 FOXK2 ZBTB40 SIN3A NRF1 POLR2G SP1 NCOR1 BCLAF1 JUND FOS MBNL1 NONHSAG036411.2 TMEM14EP MBNL1-AS1 LOC105374162 lnc-MBNL1-3
GH03J152314 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 19.8 +21.3 21326 9.9 EP300 FOS ZBTB11 DNMT1 MEF2C CUX1 MYC RCOR1 JUN ATF2 TMEM14EP MBNL1-AS1 MBNL1 LOC105374162 lnc-IGSF10-8
GH03J152283 Promoter/Enhancer 1.1 Ensembl ENCODE dbSUPER 17.5 +57.4 57374 1.6 ZBTB40 ZNF217 NFIC NR2F2 HDAC2 NR2F1 DPF2 NFIB NR2F6 IKZF1 TMEM14EP MBNL1-AS1 NONHSAG036411.2 lnc-MBNL1-3 MBNL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM14EP on UCSC Golden Path with GeneCards custom track

Genomic Locations for TMEM14EP Gene

Genomic Locations for TMEM14EP Gene
chr3:152,339,695-152,340,990
(GRCh38/hg38)
Size:
1,296 bases
Orientation:
Minus strand
chr3:152,057,484-152,058,779
(GRCh37/hg19)
Size:
1,296 bases
Orientation:
Minus strand

Genomic View for TMEM14EP Gene

Genes around TMEM14EP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM14EP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM14EP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM14EP Gene

Proteins for TMEM14EP Gene

  • Protein details for TMEM14EP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXP3-TM14E_HUMAN
    Recommended name:
    Transmembrane protein 14EP
    Protein Accession:
    Q6UXP3

    Protein attributes for TMEM14EP Gene

    Size:
    125 amino acids
    Molecular mass:
    13608 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM14EP Gene

Post-translational modifications for TMEM14EP Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM14EP Gene

Domains & Families for TMEM14EP Gene

Protein Domains for TMEM14EP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM14EP Gene

GenScript: Design optimal peptide antigens:
  • Transmembrane protein 14E (TM14E_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6UXP3

UniProtKB/Swiss-Prot:

TM14E_HUMAN :
  • Belongs to the TMEM14 family.
Family:
  • Belongs to the TMEM14 family.
genes like me logo Genes that share domains with TMEM14EP: view

No data available for Gene Families for TMEM14EP Gene

Function for TMEM14EP Gene

Phenotypes From GWAS Catalog for TMEM14EP Gene

miRNA for TMEM14EP Gene

miRTarBase miRNAs that target TMEM14EP

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM14EP Gene

Localization for TMEM14EP Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM14EP Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM14EP gene
Compartment Confidence
extracellular 2
mitochondrion 1
cytosol 1
nucleus 0
golgi apparatus 0

Gene Ontology (GO) - Cellular Components for TMEM14EP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM14EP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM14EP Gene

Pathways & Interactions for TMEM14EP Gene

PathCards logo

SuperPathways for TMEM14EP Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for TMEM14EP Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TMEM14EP Gene

Drugs & Compounds for TMEM14EP Gene

No Compound Related Data Available

Transcripts for TMEM14EP Gene

mRNA/cDNA for TMEM14EP Gene

1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM14EP Gene

No ASD Table

Relevant External Links for TMEM14EP Gene

GeneLoc Exon Structure for
TMEM14EP

Expression for TMEM14EP Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM14EP

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM14EP Gene

Orthologs for TMEM14EP Gene

Evolution for TMEM14EP Gene

ENSEMBL:
Gene Tree for TMEM14EP (if available)
TreeFam:
Gene Tree for TMEM14EP (if available)

No data available for Orthologs for TMEM14EP Gene

Paralogs for TMEM14EP Gene

No data available for Paralogs for TMEM14EP Gene

Variants for TMEM14EP Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMEM14EP Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
rs13077912 - p.Leu82Pro

Structural Variations from Database of Genomic Variants (DGV) for TMEM14EP Gene

Variant ID Type Subtype PubMed ID
nsv483030 CNV gain 15286789
nsv954493 CNV duplication 24416366

Variation tolerance for TMEM14EP Gene

Residual Variation Intolerance Score: 80.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.27; 40.72% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM14EP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM14EP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Additional dbSNP identifiers (rs#s) for TMEM14EP Gene

Disorders for TMEM14EP Gene

Additional Disease Information for TMEM14EP

No disorders were found for TMEM14EP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM14EP Gene

Publications for TMEM14EP Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4 54
  2. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E … Simpson AJ (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 54

Products for TMEM14EP Gene

Sources for TMEM14EP Gene