Aliases for TMEM132E-DT Gene

Data sources for TMEM132E-DT Gene:

RNA type for TMEM132E-DT Gene

lncRNA

Aliases for TMEM132E-DT Gene

External Ids for TMEM132E-DT Gene

Previous HGNC Symbols for TMEM132E-DT Gene

  • C17orf102

Summaries for TMEM132E-DT Gene

GeneCards Summary for TMEM132E-DT Gene

TMEM132E-DT (TMEM132E Divergent Transcript) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TMEM132E-DT Gene

Genomics for TMEM132E-DT Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TMEM132E-DT Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J034578 Promoter/Enhancer 1.5 Ensembl ENCODE CraniofacialAtlas 250.7 -0.4 -423 1.6 ZNF600 ZNF223 ZIC2 ZBTB10 ZNF341 ZEB1 ZNF610 SP2 KLF16 ZSCAN5A TMEM132E TMEM132E-DT LIG3 ZNF830 CCL7 lnc-CCL13-2
GH17J034412 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 10.2 +166.1 166068 3.4 MYC ZNF592 MNT TAF9B MAFF TAL1 ELF1 ZNF316 NFE2 RELA CCL2 CCL7 TMEM132E TMEM132E-DT LIG3 ASIC2 CCL1 CCL8 lnc-CCL13-1 piR-38583-008
GH17J034882 Enhancer 1 Ensembl ENCODE 10.3 -305.0 -305032 3.2 MYC IKZF1 NCOR1 NFIC ZIC2 HES1 BHLHE40 ARNT NBN RUNX1 CCT6B TMEM132E TMEM132E-DT LIG3 HSALNG0115895 piR-31162-199 LOC105371742 ZNF830
GH17J034886 Enhancer 1 Ensembl ENCODE 10.3 -307.7 -307732 1.4 MYC NCOR1 NFIC HES1 BHLHE40 MNT TAL1 ZNF316 SKIL MYNN TMEM132E TMEM132E-DT CCT6B LIG3 HSALNG0115895 piR-31162-199 LOC105371742 ZNF830
GH17J034637 Enhancer 0.7 ENCODE 11.8 -59.0 -59048 0.2 ZNF654 ZNF600 REST CTCF RAD21 SMC3 YY1 ZNF143 ZNF18 ZFP69B TMEM132E TMEM132E-DT HSALNG0115887 HSALNG0115886 ZNF830
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TMEM132E-DT on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TMEM132E-DT

Genomic Locations for TMEM132E-DT Gene

Latest Assembly
chr17:34,574,122-34,579,369
(GRCh38/hg38)
Size:
5,248 bases
Orientation:
Minus strand

Previous Assembly
chr17:32,901,142-32,906,388
(GRCh37/hg19 by Entrez Gene)
Size:
5,247 bases
Orientation:
Minus strand

chr17:32,901,142-32,906,388
(GRCh37/hg19 by Ensembl)
Size:
5,247 bases
Orientation:
Minus strand

Genomic View for TMEM132E-DT Gene

Genes around TMEM132E-DT on UCSC Golden Path with GeneCards custom track
TMEM132E-DT in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
TMEM132E-DT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM132E-DT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM132E-DT Gene

Proteins for TMEM132E-DT Gene

  • Protein details for TMEM132E-DT Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUQ5-CQ102_HUMAN
    Recommended name:
    Uncharacterized protein C17orf102
    Protein Accession:
    A2RUQ5
    Secondary Accessions:
    • A5PKX0
    • Q6ZTB3

    Protein attributes for TMEM132E-DT Gene

    Size:
    167 amino acids
    Molecular mass:
    17761 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM132E-DT Gene

Post-translational modifications for TMEM132E-DT Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM132E-DT Gene

Domains & Families for TMEM132E-DT Gene

Gene Families for TMEM132E-DT Gene

genes like me logo Genes that share domains with TMEM132E-DT: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TMEM132E-DT Gene

Function for TMEM132E-DT Gene

Phenotypes From GWAS Catalog for TMEM132E-DT Gene

genes like me logo Genes that share phenotypes with TMEM132E-DT: view

CRISPR products for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM132E-DT

Cell Lines for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM132E-DT Gene

Localization for TMEM132E-DT Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM132E-DT gene
Compartment Confidence
extracellular 1
mitochondrion 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TMEM132E-DT Gene

Pathways & Interactions for TMEM132E-DT Gene

PathCards logo

SuperPathways for TMEM132E-DT Gene

No Data Available

Interacting Proteins for TMEM132E-DT Gene

Selected Interacting proteins: A2RUQ5-CQ102_HUMAN for TMEM132E-DT Gene via IID

Gene Ontology (GO) - Biological Process for TMEM132E-DT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM132E-DT Gene

Drugs & Compounds for TMEM132E-DT Gene

No Compound Related Data Available

Transcripts for TMEM132E-DT Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TMEM132E-DT Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS00007CD4C6_9606 lncRNA 3999 3

RefSeq: NR_160787,

Ensembl: ENST00000623254 (view in UCSC) ,

LNCipedia: lnc-CCL1-3:11,

URS0000EF1FFE_9606 lncRNA 2979 1

Ensembl: ENST00000661426 (view in UCSC) ,

TMEM132E-DT in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TMEM132E-DT Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :

CRISPR products for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TMEM132E-DT

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM132E-DT Gene

No ASD Table

Relevant External Links for TMEM132E-DT Gene

GeneLoc Exon Structure for
TMEM132E-DT

Expression for TMEM132E-DT Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TMEM132E-DT

SOURCE GeneReport for Unigene cluster for TMEM132E-DT Gene:

Hs.514090
No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM132E-DT Gene

Orthologs for TMEM132E-DT Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TMEM132E-DT Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C17H17orf102 29
  • 99.4 (n)
C17orf102 30
  • 98 (a)
OneToOne
Species where no ortholog for TMEM132E-DT was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TMEM132E-DT Gene

ENSEMBL:
Gene Tree for TMEM132E-DT (if available)
TreeFam:
Gene Tree for TMEM132E-DT (if available)
Alliance of Genome Resources:
Additional Orthologs for TMEM132E-DT

Paralogs for TMEM132E-DT Gene

No data available for Paralogs for TMEM132E-DT Gene

Variants for TMEM132E-DT Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TMEM132E-DT Gene

SNP ID Clinical significance and condition Chr 17 pos Variation AA Info Type
rs58529418 -- p.Gly98Arg
rs887230 -- p.Arg155Lys

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TMEM132E-DT Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TMEM132E-DT Gene

Variant ID Type Subtype PubMed ID
dgv3141n100 CNV gain 25217958
esv33292 CNV gain 17666407
esv3572553 CNV gain 25503493
esv3582611 CNV loss 25503493
nsv1055479 CNV gain 25217958
nsv519297 CNV gain 19592680
nsv574714 CNV gain 21841781

Variation tolerance for TMEM132E-DT Gene

Residual Variation Intolerance Score: 80.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.82; 67.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM132E-DT Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM132E-DT
Leiden Open Variation Database (LOVD)
TMEM132E-DT

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM132E-DT Gene

Disorders for TMEM132E-DT Gene

Additional Disease Information for TMEM132E-DT

No disorders were found for TMEM132E-DT Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM132E-DT Gene

Publications for TMEM132E-DT Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

No data available for Mastermind for TMEM132E-DT Gene

Products for TMEM132E-DT Gene

Sources for TMEM132E-DT Gene