External Ids for TMEM119 Gene
Previous GeneCards Identifiers for TMEM119 Gene
GeneCards Summary for TMEM119 Gene
TMEM119 (Transmembrane Protein 119) is a Protein Coding gene. Among its related pathways are Microglia Activation During Neuroinflammation: Steady-State Microglia.
UniProtKB/Swiss-Prot for TMEM119 Gene
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).