Aliases for TMED1 Gene
External Ids for TMED1 Gene
Previous GeneCards Identifiers for TMED1 Gene
This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
GeneCards Summary for TMED1 Gene
TMED1 (Transmembrane P24 Trafficking Protein 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is TMED5.
UniProtKB/Swiss-Prot Summary for TMED1 Gene
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.