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Aliases for TMCO5B Gene

Aliases for TMCO5B Gene

  • Transmembrane And Coiled-Coil Domains 5B (Pseudogene) 2 3 5
  • Transmembrane And Coiled-Coil Domains 5B 2

External Ids for TMCO5B Gene

Previous GeneCards Identifiers for TMCO5B Gene

  • GC00U922816
  • GC15U900969
  • GC15M031315
  • GC15M033527

Summaries for TMCO5B Gene

GeneCards Summary for TMCO5B Gene

TMCO5B (Transmembrane And Coiled-Coil Domains 5B (Pseudogene)) is a Pseudogene.

Additional gene information for TMCO5B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMCO5B Gene

Genomics for TMCO5B Gene

GeneHancer (GH) Regulatory Elements for TMCO5B Gene

Promoters and enhancers for TMCO5B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I033241 Enhancer 0.7 ENCODE 12.6 +4.1 4118 4.6 CTCF FOXA2 ZBTB21 INSM2 POLR2A ATF7 FOSL2 FOS ZNF639 RFX1 TMCO5B RYR3 LOC105370759
GH15I032700 Enhancer 1 ENCODE dbSUPER 5.3 +546.2 546211 1.2 CLOCK FOXA2 RAD21 YY1 FOS HMG20B RXRA SP5 REST PPARG LOC105370757 SCG5 ENSG00000212415 TMCO5B LOC105370756 GREM1
GH15I033278 Enhancer 0.9 Ensembl ENCODE 5.5 -31.7 -31706 1.7 ZBTB6 JUN ZIC2 HIC1 FOSL1 GLIS2 PATZ1 FOSL2 FOS ZNF398 RYR3 ENSG00000212415 TMCO5B LOC101928134
GH15I033293 Enhancer 0.3 Ensembl 4.7 -46.3 -46280 0.2 YY1 TMCO5B LOC101928134
GH15I033194 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 0.2 +52.7 52653 1.5 PKNOX1 ATF1 SIN3A ZNF335 TCF12 GLIS2 EGR1 FOS CREM SP3 FMN1 LOC105370759 ENSG00000259287 LOC101928042 TMCO5B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TMCO5B on UCSC Golden Path with GeneCards custom track

Genomic Locations for TMCO5B Gene

Genomic Locations for TMCO5B Gene
12,070 bases
Minus strand

Genomic View for TMCO5B Gene

Genes around TMCO5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMCO5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMCO5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMCO5B Gene

Proteins for TMCO5B Gene

  • Protein details for TMCO5B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane and coiled-coil domain-containing protein 5B
    Protein Accession:

    Protein attributes for TMCO5B Gene

    307 amino acids
    Molecular mass:
    35763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMCO5B Gene

Post-translational modifications for TMCO5B Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMCO5B Gene

Domains & Families for TMCO5B Gene

Protein Domains for TMCO5B Gene


Suggested Antigen Peptide Sequences for TMCO5B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMCO5 family.
  • Belongs to the TMCO5 family.
genes like me logo Genes that share domains with TMCO5B: view

No data available for Gene Families for TMCO5B Gene

Function for TMCO5B Gene

Phenotypes From GWAS Catalog for TMCO5B Gene

Phenotypes for TMCO5B Gene

GenomeRNAi human phenotypes for TMCO5B:
genes like me logo Genes that share phenotypes with TMCO5B: view

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No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMCO5B Gene

Localization for TMCO5B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMCO5B Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMCO5B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMCO5B: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TMCO5B Gene

Pathways & Interactions for TMCO5B Gene

SuperPathways for TMCO5B Gene

No Data Available

Interacting Proteins for TMCO5B Gene

Gene Ontology (GO) - Biological Process for TMCO5B Gene


No data available for Pathways by source and SIGNOR curated interactions for TMCO5B Gene

Drugs & Compounds for TMCO5B Gene

No Compound Related Data Available

Transcripts for TMCO5B Gene

mRNA/cDNA for TMCO5B Gene

(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMCO5B Gene

Transmembrane and coiled-coil domains 5B, pseudogene:
Representative Sequences:

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Alternative Splicing Database (ASD) splice patterns (SP) for TMCO5B Gene

No ASD Table

Relevant External Links for TMCO5B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMCO5B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMCO5B Gene

mRNA differential expression in normal tissues according to GTEx for TMCO5B Gene

This gene is overexpressed in Testis (x51.7).

Protein differential expression in normal tissues from HIPED for TMCO5B Gene

This gene is overexpressed in Blymphocyte (52.7) and Frontal cortex (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMCO5B Gene

Protein tissue co-expression partners for TMCO5B Gene

NURSA nuclear receptor signaling pathways regulating expression of TMCO5B Gene:


SOURCE GeneReport for Unigene cluster for TMCO5B Gene:

genes like me logo Genes that share expression patterns with TMCO5B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMCO5B Gene

Orthologs for TMCO5B Gene

Evolution for TMCO5B Gene

Gene Tree for TMCO5B (if available)
Gene Tree for TMCO5B (if available)

No data available for Orthologs for TMCO5B Gene

Paralogs for TMCO5B Gene

(1) SIMAP similar genes for TMCO5B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMCO5B: view

No data available for Paralogs for TMCO5B Gene

Variants for TMCO5B Gene

Sequence variations from dbSNP and Humsavar for TMCO5B Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000351737 -- 33,237,655(-) G/T intron_variant
rs1000384426 -- 33,237,389(-) G/A intron_variant
rs1000431490 -- 33,236,003(-) A/G downstream_transcript_variant
rs1000539833 -- 33,243,235(-) G/A intron_variant
rs1000715055 -- 33,248,627(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TMCO5B Gene

Variant ID Type Subtype PubMed ID
nsv832963 CNV gain 17160897
nsv1052620 CNV gain 25217958
esv3892662 CNV gain 25118596
esv33337 CNV gain+loss 17666407
dgv4456n54 CNV gain 21841781

Additional Variant Information for TMCO5B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TMCO5B Gene

Disorders for TMCO5B Gene

Additional Disease Information for TMCO5B

No disorders were found for TMCO5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMCO5B Gene

Publications for TMCO5B Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients. (PMID: 19096130) Kitahara K … Ota M (Disease markers 2008) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for TMCO5B Gene

Sources for TMCO5B Gene

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