Aliases for TMBIM6 Gene
External Ids for TMBIM6 Gene
Previous HGNC Symbols for TMBIM6 Gene
Previous GeneCards Identifiers for TMBIM6 Gene
GeneCards Summary for TMBIM6 Gene
TMBIM6 (Transmembrane BAX Inhibitor Motif Containing 6) is a Protein Coding gene. Among its related pathways are Pathogenic Escherichia coli infection. Gene Ontology (GO) annotations related to this gene include enzyme binding and endoribonuclease inhibitor activity. An important paralog of this gene is GHITM.
UniProtKB/Swiss-Prot Summary for TMBIM6 Gene
Suppressor of apoptosis (PubMed:21075086). Modulates unfolded protein response signaling (PubMed:21075086). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed:22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).