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TMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4) is a Protein Coding gene. Diseases associated with TMBIM4 include Lassa Fever. An important paralog of this gene is ENSG00000228144.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 19553469 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000139 | Golgi membrane | IEA | -- |
GO:0005794 | Golgi apparatus | IDA | -- |
GO:0005795 | Golgi stack | IDA | 17319741 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006915 | apoptotic process | IEA | -- |
GO:0043066 | negative regulation of apoptotic process | IMP | 17319741 |
GO:0050848 | regulation of calcium-mediated signaling | IDA | 19553469 |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TMBIM4 30 |
|
||
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | TMBIM4 30 |
|
||
-- 31 |
|
OneToMany | |||
Cow (Bos Taurus) |
Mammalia | TMBIM4 30 |
|
||
CGI-119 31 |
|
OneToMany | |||
Rat (Rattus norvegicus) |
Mammalia | Tmbim4 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Tmbim4 30 17 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
TMBIM4 30 |
|
||||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tmbim4 30 |
|
||
Str.11131 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.6302 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | tmbim4 30 31 |
|
OneToMany | |
zgc66343 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG30379 31 |
|
ManyToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | tmbi-4 30 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BXI1 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT4G15470 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os05g0402300 30 |
|
||
Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | bxi1 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8799 31 |
|
OneToMany | |
Bread mold (Neurospora crassa) |
Ascomycetes | NCU02463 30 |
|
||
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.4667 30 |
|
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11176070 | - | p.Ala2Val | |||
rs8793 | - | p.Ile88Thr |
Disorder | Aliases | PubMed IDs |
---|---|---|
lassa fever |
|
|