Aliases for TM7SF3 Gene
External Ids for TM7SF3 Gene
Previous GeneCards Identifiers for TM7SF3 Gene
GeneCards Summary for TM7SF3 Gene
TM7SF3 (Transmembrane 7 Superfamily Member 3) is a Protein Coding gene. Diseases associated with TM7SF3 include Basal Cell Nevus Syndrome.
UniProtKB/Swiss-Prot Summary for TM7SF3 Gene
Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells (PubMed:21853325). Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) (PubMed:27740623).