Aliases for TM4SF4 Gene
Aliases for TM4SF4 Gene
External Ids for TM4SF4 Gene
- HGNC: 11856
- Entrez Gene: 7104
- Ensembl: ENSG00000169903
- OMIM: 606567
- UniProtKB: P48230
Previous GeneCards Identifiers for TM4SF4 Gene
- GC03P146120
- GC03P150076
- GC03P150473
- GC03P150512
- GC03P150674
- GC03P149191
- GC03P146564
Summaries for TM4SF4 Gene
-
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011]
GeneCards Summary for TM4SF4 Gene
TM4SF4 (Transmembrane 4 L Six Family Member 4) is a Protein Coding gene. An important paralog of this gene is TM4SF1.
UniProtKB/Swiss-Prot for TM4SF4 Gene
-
Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Additional gene information for TM4SF4 Gene
- Monarch Initiative
- Search for TM4SF4 at DataMed
- Search for TM4SF4 at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TM4SF4 Gene
Genomics for TM4SF4 Gene
GeneHancer (GH) Regulatory Elements for TM4SF4 Gene
Promoters and enhancers for TM4SF4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TM4SF4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TM4SF4 Gene
Genomic Locations for TM4SF4 Gene
- chr3:149,473,974-149,503,394
- (GRCh38/hg38)
- Size:
- 29,421 bases
- Orientation:
- Plus strand
- chr3:149,191,761-149,221,181
- (GRCh37/hg19)
Genomic View for TM4SF4 Gene
Genes around TM4SF4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q25.1 by Ensembl
- 3q25.1 by Entrez Gene
- 3q25.1 by HGNC
TM4SF4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TM4SF4 Gene
Proteins for TM4SF4 Gene
-
Protein details for TM4SF4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P48230-T4S4_HUMAN
- Recommended name:
- Transmembrane 4 L6 family member 4
- Protein Accession:
- P48230
- B2RDA4
Protein attributes for TM4SF4 Gene
- Size:
- 202 amino acids
- Molecular mass:
- 21396 Da
- Quaternary structure:
- No Data Available
Protein Expression for TM4SF4 Gene
Post-translational modifications for TM4SF4 Gene
- N-glycosylated. Glycosylation is required for the growth inhibitory effect.
- Glycosylation at posLast=124124 and isoforms=156
Other Protein References for TM4SF4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for TM4SF4 (TM4SF4)
-
Custom Antibody ServicesOriGene Antibodies for TM4SF4
- Novus Biologicals Antibodies for TM4SF4
-
Abcam antibodies for TM4SF4
- Invitrogen Antibodies for TM4SF4
- GeneTex TM4SF4 antibody for TM4SF4
-
Santa Cruz Biotechnology (SCBT) Antibodies for TM4SF4
Protein Products
-
OriGene Purified Proteins for TM4SF4
- Search Origene for MassSpec and Protein Over-expression Lysates for TM4SF4
- Origene Custom Protein Services for TM4SF4
- antibodies-online: Search results for 3 available TM4SF4 Proteins ranked by validation data
- Compare Top TM4SF4 Proteins
-
Quality Products:
- Search GeneTex for Proteins for TM4SF4
-
Abcam proteins for TM4SF4
Assay Products
No data available for DME Specific Peptides for TM4SF4 Gene
Domains & Families for TM4SF4 Gene
Gene Families for TM4SF4 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Protein Domains for TM4SF4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TM4SF4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P48230- Family:
-
- Belongs to the L6 tetraspanin family.
Function for TM4SF4 Gene
Molecular function for TM4SF4 Gene
- UniProtKB/Swiss-Prot Function:
- Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Phenotypes From GWAS Catalog for TM4SF4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for TM4SF4 Gene
- MGI mutant phenotypes for TM4SF4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TM4SF4:
Animal Models for TM4SF4 Gene
- MGI Knock Outs for TM4SF4:
-
- Tm4sf4 tm1.1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TM4SF4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for TM4SF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TM4SF4 gene
- Search ViGene Biosciences for TM4SF4
CRISPR Products
-
OriGene CRISPR knockouts for TM4SF4
- genomics-online: gRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- Applied Biological Materials CRISPR for TM4SF4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
- GenScript: Design CRISPR guide RNA sequences for TM4SF4
miRNA Products
- Search ViGene Biosciences for TM4SF4
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for TM4SF4
- Browse OriGene Inhibitory RNA Products For TM4SF4
- genomics-online: shRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TM4SF4 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for TM4SF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TM4SF4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TM4SF4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for TM4SF4
Cell Line Products
-
Horizon Cell Lines for TM4SF4
-
ViGene Biosciences adenoviral particle packaged cDNA for TM4SF4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TM4SF4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TM4SF4 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TM4SF4 Gene
Localization for TM4SF4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TM4SF4 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
- Cytosol (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IBA,IEA | -- |
Pathways & Interactions for TM4SF4 Gene
No Data Available
Interacting Proteins for TM4SF4 Gene
Selected Interacting proteins:
P48230-T4S4_HUMAN
ENSP00000305852
for TM4SF4 Gene via
UniProtKB
IID
STRING
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0042246 | tissue regeneration | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for TM4SF4 Gene
Transcripts for TM4SF4 Gene
mRNA/cDNA for TM4SF4 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (198) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TM4SF4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TM4SF4
- genomics-online: gRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- Applied Biological Materials CRISPR for TM4SF4
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
- GenScript: Design CRISPR guide RNA sequences for TM4SF4
miRNA Products
- Search ViGene Biosciences for TM4SF4
Inhibitory RNA Products
- Origene RNAi and shrna products in human, mouse, rat for TM4SF4
- Browse OriGene Inhibitory RNA Products For TM4SF4
- genomics-online: shRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TM4SF4 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for TM4SF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TM4SF4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TM4SF4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for TM4SF4
Expression for TM4SF4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Intestine (Gastrointestinal Tract)
-
Gall Bladder (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for TM4SF4 Gene
This gene is overexpressed in Liver (x37.3), Pancreas (x8.3), and Small Intestine - Terminal Ileum (x4.8).
This gene is overexpressed in Fetal gut (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TM4SF4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of TM4SF4 Gene:
TM4SF4SOURCE GeneReport for Unigene cluster for TM4SF4 Gene:
Hs.133527mRNA Expression by UniProt/SwissProt for TM4SF4 Gene:
P48230-T4S4_HUMAN
Tissue specificity:
Jejunum and liver.
Evidence on tissue expression from TISSUES for TM4SF4 Gene
- Intestine(4.6)
- Liver(4.6)
- Pancreas(4.4)
- Gall bladder(2.6)
Primer Products
-
OriGene qPCR primer pairs for TM4SF4
-
OriGene qPCR primer pairs and template standards for TM4SF4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TM4SF4 Gene
Orthologs for TM4SF4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TM4SF4 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TM4SF4 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Tm4sf4 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tm4sf4 33 |
|
||
| cow (Bos Taurus) |
Mammalia | TM4SF4 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | TM4SF4 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TM4SF4 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TM4SF4 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TM4SF4 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tm4sf4 33 |
|
||
| MGC75723 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | tm4sf4-prov 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | tm4sf4 33 34 |
|
||
| Dr.3563 33 |
|
- Species where no ortholog for TM4SF4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for TM4SF4 Gene
Variants for TM4SF4 Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000045441 | -- | 149,502,213(+) | T/A | intron_variant | |
| rs1000154229 | -- | 149,480,987(+) | G/A | intron_variant | |
| rs1000323737 | -- | 149,475,205(+) | T/A | intron_variant | |
| rs1000519063 | -- | 149,503,570(+) | G/A | downstream_transcript_variant | |
| rs1000797714 | -- | 149,492,508(+) | C/T | intron_variant |
Residual Variation Intolerance Score:
78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.00;
20.62% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TM4SF4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TM4SF4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TM4SF4 Gene
Disorders for TM4SF4 Gene
Additional Disease Information for TM4SF4
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for TM4SF4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TM4SF4 Gene
Publications for TM4SF4 Gene
- A tetraspan membrane glycoprotein produced in the human intestinal epithelium and liver that can regulate cell density-dependent proliferation. (PMID: 7665614) Wice BM … Gordon JI (The Journal of biological chemistry 1995) 2 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment. (PMID: 28129652) Cheong JG … Lee JW (Oncotarget 2017) 3 58
- A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells. (PMID: 26272612) Dai FF … Wheeler MB (The Journal of biological chemistry 2015) 3 58
Products for TM4SF4 Gene
- R&D Systems Antibodies for TM4SF4 (TM4SF4)
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- Custom Antibody ServicesOriGene Antibodies for TM4SF4
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TM4SF4
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- OriGene qPCR primer pairs and template standards for TM4SF4
- OriGene qPCR primer pairs for TM4SF4
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- GenScript: Design CRISPR guide RNA sequences for TM4SF4
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for TM4SF4
- VectorBuilder custom plasmid, inducible vectors for TM4SF4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TM4SF4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 34 available TM4SF4 Antibodies ranked by validation data
- Compare Top TM4SF4 Antibodies
- antibodies-online: Search results for available TM4SF4 related products ranked by validation data
- antibodies-online: Search results for 3 available TM4SF4 Proteins ranked by validation data
- Compare Top TM4SF4 Proteins
- Quality Products:
- GeneTex TM4SF4 antibody for TM4SF4
- Search GeneTex for Proteins for TM4SF4
- ViGene Biosciences adenoviral particle packaged cDNA for TM4SF4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TM4SF4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TM4SF4 gene
- Search ViGene Biosciences for TM4SF4
- Santa Cruz Biotechnology (SCBT) Antibodies for TM4SF4
- Search Santa Cruz Biotechnology (SCBT) for TM4SF4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
- Horizon Cell Lines for TM4SF4
- genomics-online: cdna clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- orf clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- genomics-online: gRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- genomics-online: primer clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
- genomics-online: shRNA clones - Search results for 93 available TM4SF4 gene related products
- Overview of 93 available TM4SF4 gene related products
Sources for TM4SF4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems