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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This enc... See more...
Aliases for TM4SF4 Gene
Aliases for TM4SF4 Gene
External Ids for TM4SF4 Gene
- HGNC: 11856
- Entrez Gene: 7104
- Ensembl: ENSG00000169903
- OMIM: 606567
- UniProtKB: P48230
Previous GeneCards Identifiers for TM4SF4 Gene
- GC03P146120
- GC03P150076
- GC03P150473
- GC03P150512
- GC03P150674
- GC03P149191
- GC03P146564
Summaries for TM4SF4 Gene
-
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011]
GeneCards Summary for TM4SF4 Gene
TM4SF4 (Transmembrane 4 L Six Family Member 4) is a Protein Coding gene. An important paralog of this gene is TM4SF1.
UniProtKB/Swiss-Prot Summary for TM4SF4 Gene
-
Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Additional gene information for TM4SF4 Gene
- HGNC(11856)
- Entrez Gene(7104)
- Ensembl(ENSG00000169903)
- OMIM(606567)
- UniProtKB(P48230)
- Open Targets Platform(ENSG00000169903)
- Monarch Initiative
- Search for TM4SF4 at DataMed
- Search for TM4SF4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TM4SF4 Gene
Genomics for TM4SF4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TM4SF4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TM4SF4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TM4SF4
- Top Transcription factor binding sites by QIAGEN in the TM4SF4 gene promoter:
-
- AML1a
- ATF6
- C/EBPbeta
- E47
- Evi-1
- FOXO3
- FOXO3a
- FOXO3b
- HFH-1
- Nkx6-1
Genomic Locations for TM4SF4 Gene
Genomic Locations for TM4SF4 Gene
- chr3:149,474,697-149,503,394
- (GRCh38/hg38)
- Size:
- 28,698 bases
- Orientation:
- Plus strand
- chr3:149,191,761-149,221,181
- (GRCh37/hg19)
- Size:
- 29,421 bases
- Orientation:
- Plus strand
Genomic View for TM4SF4 Gene
Genes around TM4SF4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q25.1 by HGNC
- 3q25.1 by Entrez Gene
- 3q25.1 by Ensembl
TM4SF4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TM4SF4 Gene
Proteins for TM4SF4 Gene
-
Protein details for TM4SF4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P48230-T4S4_HUMAN
- Recommended name:
- Transmembrane 4 L6 family member 4
- Protein Accession:
- P48230
- B2RDA4
Protein attributes for TM4SF4 Gene
- Size:
- 202 amino acids
- Molecular mass:
- 21396 Da
- Quaternary structure:
- No Data Available
Protein Expression for TM4SF4 Gene
Post-translational modifications for TM4SF4 Gene
- N-glycosylated. Glycosylation is required for the growth inhibitory effect.
-
Glycosylation at Asn124 and Asn156
- NX_P48230 (NX_P48230-1)
- Modification sites at PhosphoSitePlus
Other Protein References for TM4SF4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for TM4SF4
- Novus Biologicals Antibodies for TM4SF4
-
Abcam antibodies for TM4SF4
- Invitrogen Antibodies for TM4SF4 (AFLGC-TM4SF4)
-
Santa Cruz Biotechnology (SCBT) Antibodies for TM4SF4
- Sino Biological Antibodies for TM4SF4
Protein Products
-
OriGene Purified Proteins for TM4SF4
- Search Origene for MassSpec and Protein Over-expression Lysates for TM4SF4
- Origene Custom Protein Services for TM4SF4
- antibodies-online: Show 3 available TM4SF4 Proteins ranked by validation data
- Compare Top TM4SF4 Proteins
-
Quality Products:
-
Abcam proteins for TM4SF4
Assay Products
-
Signalway ELISA kits for TM4SF4
No data available for DME Specific Peptides for TM4SF4 Gene
Domains & Families for TM4SF4 Gene
Gene Families for TM4SF4 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Protein Domains for TM4SF4 Gene
- InterPro:
- Blocks:
-
- L6 membrane
- ProtoNet:
Suggested Antigen Peptide Sequences for TM4SF4 Gene
- GenScript: Design optimal peptide antigens:
-
- Intestine and liver tetraspan membrane protein (T4S4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P48230- Family:
-
- Belongs to the L6 tetraspanin family.
Function for TM4SF4 Gene
Molecular function for TM4SF4 Gene
- UniProtKB/Swiss-Prot Function:
- Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.
Phenotypes From GWAS Catalog for TM4SF4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for TM4SF4 Gene
- MGI mutant phenotypes for TM4SF4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TM4SF4:
Animal Models for TM4SF4 Gene
- MGI Knock Outs for TM4SF4:
-
- Tm4sf4 Tm4sf4<tm1.1(KOMP)Vlcg>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TM4SF4 - Select products 50% OFF >
- * TM4SF4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TM4SF4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TM4SF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TM4SF4
- Browse OriGene Inhibitory RNA Products For TM4SF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TM4SF4
Clone Products
- Applied Biological Materials (abm): Clones for TM4SF4 - Select products 50% OFF >
- * TM4SF4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TM4SF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TM4SF4
Cell Line Products
-
Horizon Cell Lines for TM4SF4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TM4SF4 Gene
Localization for TM4SF4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TM4SF4 Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| extracellular | 1 |
| cytoskeleton | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Cytosol (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,IBA | 21873635 |
Pathways & Interactions for TM4SF4 Gene
Interacting Proteins for TM4SF4 Gene
Selected Interacting proteins:
P48230-T4S4_HUMAN
ENSP00000305852
for TM4SF4 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TM4SF4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0042246 | tissue regeneration | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for TM4SF4 Gene
Transcripts for TM4SF4 Gene
mRNA/cDNA for TM4SF4 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000305354 1491 nts (view in UCSC)
- ENST00000463068 456 nts (view in UCSC)
- ENST00000465758 422 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TM4SF4 - Select products 50% OFF >
- * TM4SF4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TM4SF4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TM4SF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TM4SF4
- Browse OriGene Inhibitory RNA Products For TM4SF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TM4SF4
Clone Products
- Applied Biological Materials (abm): Clones for TM4SF4 - Select products 50% OFF >
- * TM4SF4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TM4SF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TM4SF4
Relevant External Links for TM4SF4 Gene
- GeneLoc Exon Structure for
- TM4SF4
Expression for TM4SF4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Endocrine Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Intestine (Gastrointestinal Tract)
-
Gall Bladder (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for TM4SF4 Gene
This gene is overexpressed in Liver (x37.3), Pancreas (x8.3), and Small Intestine - Terminal Ileum (x4.8).
This gene is overexpressed in Fetal gut (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TM4SF4 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TM4SF4
SOURCE GeneReport for Unigene cluster for TM4SF4 Gene:
Hs.133527mRNA Expression by UniProt/SwissProt for TM4SF4 Gene:
P48230-T4S4_HUMAN
Tissue specificity:
Jejunum and liver.
Evidence on tissue expression from TISSUES for TM4SF4 Gene
- Liver(4.6)
- Intestine(4.6)
- Pancreas(4.5)
- Gall bladder(3)
- Stomach(2.1)
Primer Products
-
OriGene qPCR primer pairs for TM4SF4
-
OriGene qPCR primer pairs and template standards for TM4SF4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TM4SF4 Gene
Orthologs for TM4SF4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TM4SF4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TM4SF4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tm4sf4 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tm4sf4 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | TM4SF4 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TM4SF4 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TM4SF4 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TM4SF4 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TM4SF4 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tm4sf4 30 |
|
||
| MGC75723 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | tm4sf4-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tm4sf4 30 31 |
|
OneToOne | |
| Dr.3563 30 |
|
- Species where no ortholog for TM4SF4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TM4SF4 Gene
- ENSEMBL:
- Gene Tree for TM4SF4 (if available)
- TreeFam:
- Gene Tree for TM4SF4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TM4SF4: view image
Paralogs for TM4SF4 Gene
Variants for TM4SF4 Gene
Residual Variation Intolerance Score:
78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.00;
20.62% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TM4SF4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TM4SF4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TM4SF4 Gene
Disorders for TM4SF4 Gene
Additional Disease Information for TM4SF4
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for TM4SF4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TM4SF4 Gene
Publications for TM4SF4 Gene
- A tetraspan membrane glycoprotein produced in the human intestinal epithelium and liver that can regulate cell density-dependent proliferation. (PMID: 7665614) Wice BM … Gordon JI (The Journal of biological chemistry 1995) 2 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment. (PMID: 28129652) Cheong JG … Lee JW (Oncotarget 2017) 3
ExternalLinks
Products for TM4SF4 Gene
- Custom Antibody ServicesOriGene Antibodies for TM4SF4
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TM4SF4
- Search Origene for MassSpec and Protein Over-expression Lysates for TM4SF4
- Origene Custom Protein Services for TM4SF4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TM4SF4
- Browse OriGene Inhibitory RNA Products For TM4SF4
- OriGene qPCR primer pairs for TM4SF4
- OriGene qPCR primer pairs and template standards for TM4SF4
- OriGene CRISPR knockouts for TM4SF4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TM4SF4
- Sino Biological Human cDNA Clone for TM4SF4
- Browse Sino Biological Recombinant Proteins
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- Sino Biological Antibodies for TM4SF4
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TM4SF4
- Novus Biologicals proteins and lysates for TM4SF4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for TM4SF4
- Abcam proteins for TM4SF4
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for TM4SF4 (AFLGC-TM4SF4)
- VectorBuilder Custom and pre-made DNA vectors for TM4SF4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TM4SF4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TM4SF4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TM4SF4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TM4SF4
- antibodies-online: Show 12 available TM4SF4 Antibodies ranked by validation data
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- antibodies-online: Search results for available TM4SF4 related products ranked by validation data
- antibodies-online: Show 3 available TM4SF4 Proteins ranked by validation data
- Compare Top TM4SF4 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for TM4SF4
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- Santa Cruz Biotechnology (SCBT) CRISPR for TM4SF4
- Horizon Cell Lines for TM4SF4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TM4SF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TM4SF4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TM4SF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TM4SF4
- Signalway ELISA kits for TM4SF4
Sources for TM4SF4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
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- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
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- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
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- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
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- (170) snOPY
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- (172) GENCODE
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- (175) Open Targets Platform
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- (177) snoDB
- (178) MirGeneDB