TLR8-AS1 Gene (RNA Gene)

TLR8 Antisense RNA 1

GC0XM012825
GIFtS:
14
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Aliases for TLR8-AS1 Gene

Data sources for TLR8-AS1 Gene:

Subcategory (RNA class) for TLR8-AS1 Gene

lncRNA

Aliases for TLR8-AS1 Gene

External Ids for TLR8-AS1 Gene

Previous GeneCards Identifiers for TLR8-AS1 Gene

  • GC0XM012922

Summaries for TLR8-AS1 Gene

GeneCards Summary for TLR8-AS1 Gene

TLR8-AS1 (TLR8 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for TLR8-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TLR8-AS1 Gene

Genomics for TLR8-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for TLR8-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TLR8-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TLR8-AS1 Gene

Latest Assembly
chrX:12,824,162-12,965,738
(GRCh38/hg38)
Size:
141,577 bases
Orientation:
Minus strand

Previous Assembly
chrX:12,920,936-12,961,419
(GRCh37/hg19 by Entrez Gene)
Size:
40,484 bases
Orientation:
Minus strand

chrX:12,920,936-12,926,452
(GRCh37/hg19 by Ensembl)
Size:
5,517 bases
Orientation:
Minus strand

Genomic View for TLR8-AS1 Gene

Genes around TLR8-AS1 on UCSC Golden Path with GeneCards custom track
TLR8-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
TLR8-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TLR8-AS1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TLR8-AS1 Gene

Proteins for TLR8-AS1 Gene

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  1. Antibodies for research
  2. Protein products for research
  3. Assay products for research

Post-translational modifications for TLR8-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TLR8-AS1 Gene

Domains & Families for TLR8-AS1 Gene

Gene Families for TLR8-AS1 Gene

HGNC:
genes like me logo Genes that share domains with TLR8-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TLR8-AS1 Gene

Function for TLR8-AS1 Gene

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  1. Animal Models for research
  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes From GWAS Catalog for TLR8-AS1 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TLR8-AS1 Gene

Localization for TLR8-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TLR8-AS1 Gene

Pathways & Interactions for TLR8-AS1 Gene

PathCards logo

SuperPathways for TLR8-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TLR8-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TLR8-AS1 Gene

Drugs & Compounds for TLR8-AS1 Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for TLR8-AS1 Gene

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  1. CRISPR products for research
  2. miRNA products for research
  3. Inhibitory RNAs for research
  4. Clone products for research

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TLR8-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000039C1A2_9606 lncRNA 1349 2

Ensembl: ENST00000451564 (view in UCSC) ,

LNCipedia: TLR8-AS1:2,

URS000075D4A0_9606 lncRNA 1589 1

RefSeq: NR_030727,

URS00008B7E94_9606 lncRNA 1589 2

LNCipedia: TLR8-AS1:1,

NONCODE: NONHSAT136273.2,

URS0001BE20B7_9606 lncRNA 4778 1

LncBook: HSALNT0280241,

URS0001BCE2B7_9606 lncRNA 3865 1

LncBook: HSALNT0280231,

TLR8-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TLR8-AS1 Gene

1 NCBI additional mRNA sequence :

CRISPR products for research

Alternative Splicing Database (ASD) splice patterns (SP) for TLR8-AS1 Gene

No ASD Table

Relevant External Links for TLR8-AS1 Gene

GeneLoc Exon Structure for
TLR8-AS1

Expression for TLR8-AS1 Gene

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  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TLR8-AS1 Gene

mRNA expression in normal human tissues for TLR8-AS1 Gene
mRNA expression by GTEx for TLR8-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for TLR8-AS1 Gene

This gene is overexpressed in Whole Blood (x21.6) and Lung (x4.8).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TLR8-AS1

SOURCE GeneReport for Unigene cluster for TLR8-AS1 Gene:

Hs.685035
genes like me logo Genes that share expression patterns with TLR8-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TLR8-AS1 Gene

Orthologs for TLR8-AS1 Gene

Evolution for TLR8-AS1 Gene

ENSEMBL:
Gene Tree for TLR8-AS1 (if available)
TreeFam:
Gene Tree for TLR8-AS1 (if available)

No data available for Orthologs for TLR8-AS1 Gene

Paralogs for TLR8-AS1 Gene

No data available for Paralogs for TLR8-AS1 Gene

Variants for TLR8-AS1 Gene

Products:

  1. SNP Genotyping and Copy Number Assays for research

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TLR8-AS1 Gene

SNP ID Clinical significance and condition Chr 0X pos Variation AA Info Type
rs151096932 Likely Benign: not provided 12,919,092(-) A/G
NM_138636.5(TLR8):c.52A>G (p.Ile18Val) 		MISSENSE
rs1569113445 Association: Osteoarthritis 12,906,527(-) G/C
NM_138636.5(TLR8):c.-180G>C
rs1569113447 Association: Osteoarthritis 12,906,538(-) T/A
NM_138636.5(TLR8):c.-169T>A
rs370464823 Likely Benign: not provided 12,920,267(-) C/T
NM_138636.5(TLR8):c.1227C>T (p.Ile409=) 		SYNONYMOUS
rs5744079 Benign: not provided 12,919,601(-) C/T
NM_138636.5(TLR8):c.561C>T (p.Cys187=) 		SYNONYMOUS

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TLR8-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TLR8-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv2223e212 CNV loss 25503493
esv3573586 CNV loss 25503493

Additional Variant Information for TLR8-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TLR8-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TLR8-AS1 Gene

Disorders for TLR8-AS1 Gene

Additional Disease Information for TLR8-AS1

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for TLR8-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TLR8-AS1 Gene

Publications for TLR8-AS1 Gene

  1. LncRNA TLR8-AS1 promotes metastasis and chemoresistance of ovarian cancer through enhancing TLR8 mRNA stability. (PMID: 32278547) Xu Q … Liu J (Biochemical and biophysical research communications 2020) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

ExternalLinks

View latest publications for TLR8-AS1 gene in Mastermind

Products for TLR8-AS1 Gene

Sources for TLR8-AS1 Gene