Aliases for TLL2 Gene
External Ids for TLL2 Gene
Previous GeneCards Identifiers for TLL2 Gene
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [provided by RefSeq, Jul 2008]
GeneCards Summary for TLL2 Gene
TLL2 (Tolloid Like 2) is a Protein Coding gene. Diseases associated with TLL2 include Powassan Encephalitis and Louping Ill. Among its related pathways are Collagen chain trimerization and Degradation of the extracellular matrix. Gene Ontology (GO) annotations related to this gene include calcium ion binding and metallopeptidase activity. An important paralog of this gene is BMP1.
UniProtKB/Swiss-Prot Summary for TLL2 Gene
Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.