Aliases for TLE2 Gene
External Ids for TLE2 Gene
Previous GeneCards Identifiers for TLE2 Gene
GeneCards Summary for TLE2 Gene
TLE2 (TLE Family Member 2, Transcriptional Corepressor) is a Protein Coding gene. Among its related pathways are Deactivation of the beta-catenin transactivating complex and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity. An important paralog of this gene is TLE1.
UniProtKB/Swiss-Prot for TLE2 Gene
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).