Aliases for TLE2 Gene
External Ids for TLE2 Gene
Previous GeneCards Identifiers for TLE2 Gene
GeneCards Summary for TLE2 Gene
TLE2 (TLE Family Member 2, Transcriptional Corepressor) is a Protein Coding gene. Among its related pathways are Signaling by Wnt and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity. An important paralog of this gene is TLE4.
UniProtKB/Swiss-Prot Summary for TLE2 Gene
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).