This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, a... See more...

Aliases for TIMP1 Gene

Aliases for TIMP1 Gene

  • TIMP Metallopeptidase Inhibitor 1 2 3 5
  • Tissue Inhibitor Of Metalloproteinases 1 3 4
  • Fibroblast Collagenase Inhibitor 3 4
  • Metalloproteinase Inhibitor 1 3 4
  • Collagenase Inhibitor 3 4
  • TIMP-1 3 4
  • CLGI 3 4
  • TIMP 3 4
  • EPA 3 4
  • EPO 2 3
  • Tissue Inhibitor Of Metalloproteinase 1 (Erythroid Potentiating Activity, Collagenase Inhibitor) 2
  • Epididymis Secretory Sperm Binding Protein 3
  • Erythroid Potentiating Activity 3
  • Erythroid-Potentiating Activity 4
  • TIMP1 5
  • HCI 3

External Ids for TIMP1 Gene

Previous HGNC Symbols for TIMP1 Gene

  • TIMP
  • CLGI

Previous GeneCards Identifiers for TIMP1 Gene

  • GC0XP046244
  • GC0XP045702
  • GC0XP046487
  • GC0XP046461
  • GC0XP047197
  • GC0XP047326
  • GC0XP047441
  • GC0XP045154

Summaries for TIMP1 Gene

Entrez Gene Summary for TIMP1 Gene

  • This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

CIViC Summary for TIMP1 Gene

GeneCards Summary for TIMP1 Gene

TIMP1 (TIMP Metallopeptidase Inhibitor 1) is a Protein Coding gene. Diseases associated with TIMP1 include Oral Submucous Fibrosis and Lung Giant Cell Carcinoma. Among its related pathways are G-protein signaling Ras family GTPases in kinase cascades (scheme) and Degradation of the extracellular matrix. Gene Ontology (GO) annotations related to this gene include cytokine activity and protease binding. An important paralog of this gene is TIMP2.

UniProtKB/Swiss-Prot Summary for TIMP1 Gene

  • Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

Gene Wiki entry for TIMP1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TIMP1 Gene

Genomics for TIMP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TIMP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ047581 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 600.7 +0.7 660 3.5 SP1 PRDM10 LEF1 IKZF1 POLR2A BACH1 JUND ZIC2 RBFOX2 PKNOX1 JA662188 TIMP1 CFP SYN1 ARAF MIR4769 ENSG00000283743
GH0XJ047482 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 12.2 -99.0 -99007 4 PRDM10 RFX1 IKZF1 POLR2A TARDBP ZHX2 GABPA ZIC2 RBFOX2 NR2C1 LINC01560 ZNF41 TIMP1 ELK1 ZNF157
GH0XJ047628 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 13.3 +47.8 47759 2 CTCF IKZF1 FOXA1 RELA RAD21 TCF12 IKZF2 TRIM22 HDAC1 PKNOX1 CFP ENSG00000283743 lnc-SYN1-1 ELK1 TIMP1 SYN1
GH0XJ047608 Enhancer 0.9 Ensembl ENCODE 19.8 +27.6 27593 4.4 TEAD4 PRDM10 ZNF512 IKZF1 POLR2A CEBPA EP300 CEBPB NFE2 ZNF316 TIMP1 UXT-AS1 SYN1 piR-60816-036 lnc-SYN1-22 ENSG00000283743
GH0XJ047500 Enhancer 1.3 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 12.2 -80.4 -80387 2.7 PRDM10 ZNF692 ZIC2 SCRT2 ZBTB20 SMARCC1 CEBPB BRCA1 SMARCA4 CHD2 TIMP1 LINC01560 CFP ARAF piR-38756-041 RF00017-8400 ZNF41
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TIMP1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TIMP1

Top Transcription factor binding sites by QIAGEN in the TIMP1 gene promoter:
  • AP-1
  • Egr-1
  • Egr-2
  • Elk-1
  • NF-kappaB1
  • Nkx2-5
  • Pax-5
  • PPAR-gamma1
  • Sox9
  • Sp1

Genomic Locations for TIMP1 Gene

Genomic Locations for TIMP1 Gene
chrX:47,582,408-47,586,789
(GRCh38/hg38)
Size:
4,382 bases
Orientation:
Plus strand
chrX:47,441,690-47,446,190
(GRCh37/hg19)
Size:
4,501 bases
Orientation:
Plus strand

Genomic View for TIMP1 Gene

Genes around TIMP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TIMP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TIMP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TIMP1 Gene

Proteins for TIMP1 Gene

  • Protein details for TIMP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01033-TIMP1_HUMAN
    Recommended name:
    Metalloproteinase inhibitor 1
    Protein Accession:
    P01033
    Secondary Accessions:
    • Q14252
    • Q9UCU1

    Protein attributes for TIMP1 Gene

    Size:
    207 amino acids
    Molecular mass:
    23171 Da
    Quaternary structure:
    • Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14. Interacts with CD63; identified in a complex with CD63 and ITGB1.

    Three dimensional structures from OCA and Proteopedia for TIMP1 Gene

neXtProt entry for TIMP1 Gene

Post-translational modifications for TIMP1 Gene

  • The activity of TIMP1 is dependent on the presence of disulfide bonds.
  • N-glycosylated.
  • Glycosylation at Asn53 and Asn101
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • TIMP1_HUMAN (367)

Other Protein References for TIMP1 Gene

Antibody Products

  • Abcam antibodies for TIMP1

No data available for DME Specific Peptides for TIMP1 Gene

Domains & Families for TIMP1 Gene

Gene Families for TIMP1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Candidate cardiovascular disease genes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for TIMP1 Gene

InterPro:
Blocks:
  • Tissue inhibitor of metalloproteinase
ProtoNet:

Suggested Antigen Peptide Sequences for TIMP1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ60276, weakly similar to Metalloproteinase inhibitor 1 (B4DJK3_HUMAN)
  • Tissue inhibitor of metalloproteinase 1 (Q58P21_HUMAN)
  • TIMP metallopeptidase inhibitor 1 (Q5H9A8_HUMAN)
  • cDNA, FLJ92204, Homo sapiens tissue inhibitor of metalloproteinase 1 (erythroidpotentiating activity, collagenase inhibitor) (TIMP1), mRNA (Q6FGX5_HUMAN)
  • Tissue inhibitor of metalloproteinases 1 (TIMP1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P01033

UniProtKB/Swiss-Prot:

TIMP1_HUMAN :
  • Belongs to the protease inhibitor I35 (TIMP) family.
Family:
  • Belongs to the protease inhibitor I35 (TIMP) family.
genes like me logo Genes that share domains with TIMP1: view

Function for TIMP1 Gene

Molecular function for TIMP1 Gene

UniProtKB/Swiss-Prot Function:
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
GENATLAS Biochemistry:
matrix metalloproteinase,tissue inhibitor 1 (erythroid potentiating activity),involved in the regulation of bone modeling and remodeling in normal developing human bone,involved in the invasive phenotype of acute myelogenous leukemia,demonstrating polymorphic X-chromosome inactivation

Gene Ontology (GO) - Molecular Function for TIMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002020 protease binding IEA,IBA 21873635
GO:0004857 enzyme inhibitor activity IEA --
GO:0005125 cytokine activity IDA 3839290
GO:0005515 protein binding IEA,IPI 2251898
GO:0008083 growth factor activity IEA --
genes like me logo Genes that share ontologies with TIMP1: view
genes like me logo Genes that share phenotypes with TIMP1: view

Animal Models for TIMP1 Gene

MGI Knock Outs for TIMP1:
  • Timp1 Timp1<tm1Pds>
  • Timp1 Timp1<tm1b(EUCOMM)Hmgu>

Animal Model Products

  • Taconic Biosciences Mouse Models for TIMP1

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TIMP1

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TIMP1 Gene

Localization for TIMP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TIMP1 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TIMP1 gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 4
plasma membrane 3
cytoskeleton 3
nucleus 3
golgi apparatus 3
mitochondrion 2
peroxisome 2
endosome 2
cytosol 2
lysosome 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TIMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA,TAS --
GO:0005581 collagen trimer IEA --
GO:0005604 basement membrane IEA --
GO:0005615 extracellular space IBA,IDA 3903517
GO:0005788 endoplasmic reticulum lumen TAS --
genes like me logo Genes that share ontologies with TIMP1: view

Pathways & Interactions for TIMP1 Gene

PathCards logo

SuperPathways for TIMP1 Gene

SuperPathway Contained pathways
1 Apoptotic Pathways in Synovial Fibroblasts
.85
.85
.84
.84
.74
.72
.66
.65
.64
.62
.61
.60
.57
.57
2 GPCR Pathway
.73
.73
.62
.59
.58
.58
.55
3 ERK Signaling
.61
.61
.58
.51
.49
4 Nanog in Mammalian ESC Pluripotency
.62
.62
.59
.48
5 CREB Pathway
.68
.68
.63
.50
genes like me logo Genes that share pathways with TIMP1: view

Pathways by source for TIMP1 Gene

5 GeneGo (Thomson Reuters) pathways for TIMP1 Gene
  • Cell adhesion_ECM remodeling
  • Development_Leptin signaling via JAK/STAT and MAPK cascades
  • Immune response IL-10 signaling pathway
  • Immune response Oncostatin M signaling via MAPK in human cells
  • Immune response_Oncostatin M signaling via JAK-Stat in human cells
56 Qiagen pathways for TIMP1 Gene
  • 14-3-3 Induced Intracellular Signaling
  • Actin-Based Motility by Rho Family GTPases
  • Activation of cAMP-Dependent PKA
  • Activation of PKA through GPCR
  • Activation of PKC through GPCR
1 Cell Signaling Technology pathway for TIMP1 Gene

SIGNOR curated interactions for TIMP1 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for TIMP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001775 cell activation IEA --
GO:0002248 connective tissue replacement involved in inflammatory response wound healing IEA --
GO:0002576 platelet degranulation TAS --
GO:0007568 aging IEA --
GO:0008284 positive regulation of cell proliferation IDA 3839290
genes like me logo Genes that share ontologies with TIMP1: view

Drugs & Compounds for TIMP1 Gene

(82) Drugs for TIMP1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(61) Additional Compounds for TIMP1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TIMP1: view

Transcripts for TIMP1 Gene

mRNA/cDNA for TIMP1 Gene

1 REFSEQ mRNAs :
18 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TIMP1

Alternative Splicing Database (ASD) splice patterns (SP) for TIMP1 Gene

No ASD Table

Relevant External Links for TIMP1 Gene

GeneLoc Exon Structure for
TIMP1

Expression for TIMP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TIMP1 Gene

mRNA differential expression in normal tissues according to GTEx for TIMP1 Gene

This gene is overexpressed in Artery - Coronary (x5.4) and Artery - Aorta (x4.1).

Protein differential expression in normal tissues from HIPED for TIMP1 Gene

This gene is overexpressed in Amniocyte (19.1), Vitreous humor (12.2), Islet of Langerhans (6.3), and Milk (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TIMP1 Gene



Protein tissue co-expression partners for TIMP1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TIMP1

SOURCE GeneReport for Unigene cluster for TIMP1 Gene:

Hs.522632

mRNA Expression by UniProt/SwissProt for TIMP1 Gene:

P01033-TIMP1_HUMAN
Tissue specificity: Detected in rheumatoid synovial fluid (at protein level).

Evidence on tissue expression from TISSUES for TIMP1 Gene

  • Lung(4.9)
  • Blood(4.7)
  • Bone marrow(4.7)
  • Pancreas(4.6)
  • Saliva(4.4)
  • Skin(4.4)
  • Heart(4.2)
  • Nervous system(4.2)
  • Bone(4.1)
  • Eye(3.9)
  • Intestine(3.9)
  • Liver(3.9)
  • Muscle(3.9)
  • Spleen(3.6)
  • Kidney(3.6)
  • Lymph node(3.4)
  • Gall bladder(3.3)
  • Adrenal gland(3.1)
  • Stomach(3.1)
  • Thyroid gland(2.8)
  • Urine(2.3)
genes like me logo Genes that share expression patterns with TIMP1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for TIMP1 Gene

Orthologs for TIMP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TIMP1 Gene

Organism Taxonomy Gene Similarity Type Details
Cow
(Bos Taurus)
Mammalia TIMP1 30 31
  • 88.41 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia TIMP1 30 31
  • 85.83 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Timp1 30 17 31
  • 78.44 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Timp1 30
  • 78.38 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia TIMP1 31
  • 49 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia TIMP1 31
  • 44 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 41 (a)
OneToMany
-- 31
  • 36 (a)
OneToMany
-- 31
  • 32 (a)
OneToMany
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7905 30
Species where no ortholog for TIMP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TIMP1 Gene

ENSEMBL:
Gene Tree for TIMP1 (if available)
TreeFam:
Gene Tree for TIMP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TIMP1: view image

Paralogs for TIMP1 Gene

Paralogs for TIMP1 Gene

(3) SIMAP similar genes for TIMP1 Gene using alignment to 8 proteins:

  • TIMP1_HUMAN
  • B4DJK3_HUMAN
  • H0Y789_HUMAN
  • Q58P21_HUMAN
  • Q5H9A7_HUMAN
  • Q5H9B4_HUMAN
  • Q5H9B5_HUMAN
  • Q6FGX5_HUMAN
genes like me logo Genes that share paralogs with TIMP1: view

Variants for TIMP1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TIMP1 Gene

SNP ID Clinical significance and condition Chr 0X pos Variation AA Info Type
720215 Benign: not provided 47,586,642(+) G/A MISSENSE_VARIANT,INTRON_VARIANT
732080 Likely Benign: not provided 47,586,641(+) C/T MISSENSE_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for TIMP1 Gene

Variation tolerance for TIMP1 Gene

Residual Variation Intolerance Score: 96.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.29; 76.48% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TIMP1 Gene

Human Gene Mutation Database (HGMD)
TIMP1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TIMP1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TIMP1 Gene

Disorders for TIMP1 Gene

MalaCards: The human disease database

(111) MalaCards diseases for TIMP1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
oral submucous fibrosis
  • oral cavity submucous fibrosis
lung giant cell carcinoma
  • giant cell carcinoma
gingivitis
  • acute gingivitis
conjunctivochalasis
gingival overgrowth
  • gingival enlargement
- elite association - COSMIC cancer census association via MalaCards
Search TIMP1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TIMP1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Tumor Gene Database
(TGDB)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with TIMP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TIMP1 Gene

Publications for TIMP1 Gene

  1. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. (PMID: 16917503) Jung KK … Kim HR (The EMBO journal 2006) 3 4 23
  2. Genes predisposing to rapid aneurysm growth. (PMID: 17182940) Powell JT (Annals of the New York Academy of Sciences 2006) 3 23 41
  3. Evaluation of MMP3 and TIMP1 as candidate genes for high myopia in young Taiwanese men. (PMID: 16935611) Liang CL … Juo SH (American journal of ophthalmology 2006) 3 23 41
  4. Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. (PMID: 15944607) Ogata T … Kuivaniemi H (Journal of vascular surgery 2005) 3 23 41
  5. Global orientation of bound MMP-3 and N-TIMP-1 in solution via residual dipolar couplings. (PMID: 12834347) Arumugam S … Van Doren SR (Biochemistry 2003) 3 4 23

Products for TIMP1 Gene

Sources for TIMP1 Gene