This locus represents naturally-occurring readthrough transcription between the adjacent TIMM23B (translocase of inner mitochondrial membrane 23 homolog B) and AGAP6 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 6) genes. Readthrough transcripts contain portions of the coding sequence for both genes and are predicted to be candidates for nonsense-mediated decay (NMD)... See more...

Aliases for TIMM23B-AGAP6 Gene

Subcategory (RNA class) for TIMM23B-AGAP6 Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for TIMM23B-AGAP6 Gene

  • TIMM23B-AGAP6 Readthrough (NMD Candidate) 2 3
  • Long Intergenic Non-Protein Coding RNA 843 2 3
  • TIMM23B-AGAP6 Readthrough 5
  • NONHSAG005891.2 91
  • NONHSAG005882.2 91
  • TIMM23B-AGAP6 5
  • HSALNG0077931 164
  • HSALNG0077935 164
  • LINC00843 3

External Ids for TIMM23B-AGAP6 Gene

Previous HGNC Symbols for TIMM23B-AGAP6 Gene

  • LINC00843

Previous GeneCards Identifiers for TIMM23B-AGAP6 Gene

  • GC10U902854

Summaries for TIMM23B-AGAP6 Gene

Entrez Gene Summary for TIMM23B-AGAP6 Gene

  • This locus represents naturally-occurring readthrough transcription between the adjacent TIMM23B (translocase of inner mitochondrial membrane 23 homolog B) and AGAP6 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 6) genes. Readthrough transcripts contain portions of the coding sequence for both genes and are predicted to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Sep 2018]

GeneCards Summary for TIMM23B-AGAP6 Gene

TIMM23B-AGAP6 (TIMM23B-AGAP6 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for TIMM23B-AGAP6 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TIMM23B-AGAP6 Gene

Genomics for TIMM23B-AGAP6 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TIMM23B-AGAP6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TIMM23B-AGAP6 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TIMM23B-AGAP6 Gene

Genomic Locations for TIMM23B-AGAP6 Gene
chr10:49,942,053-50,011,654
(GRCh38/hg38)
Size:
69,602 bases
Orientation:
Plus strand
chr10:51,732,523-51,741,813
(GRCh37/hg19)
Size:
9,291 bases
Orientation:
Plus strand

Genomic View for TIMM23B-AGAP6 Gene

Genes around TIMM23B-AGAP6 on UCSC Golden Path with GeneCards custom track
TIMM23B-AGAP6 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
TIMM23B-AGAP6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TIMM23B-AGAP6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TIMM23B-AGAP6 Gene

Proteins for TIMM23B-AGAP6 Gene

Post-translational modifications for TIMM23B-AGAP6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TIMM23B-AGAP6 Gene

Domains & Families for TIMM23B-AGAP6 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TIMM23B-AGAP6 Gene

Function for TIMM23B-AGAP6 Gene

Phenotypes From GWAS Catalog for TIMM23B-AGAP6 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TIMM23B-AGAP6 Gene

Localization for TIMM23B-AGAP6 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TIMM23B-AGAP6 Gene

Pathways & Interactions for TIMM23B-AGAP6 Gene

PathCards logo

SuperPathways for TIMM23B-AGAP6 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TIMM23B-AGAP6 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TIMM23B-AGAP6 Gene

Drugs & Compounds for TIMM23B-AGAP6 Gene

No Compound Related Data Available

Transcripts for TIMM23B-AGAP6 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TIMM23B-AGAP6 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000023A957_9606 lncRNA 562 3

Ensembl: ENST00000429104 (view in UCSC) ,

LncBook: HSALNT0162604,

NONCODE: NONHSAT013368.2,

URS00004B3DEC_9606 lncRNA 550 3

Ensembl: ENST00000444438 (view in UCSC) ,

LncBook: HSALNT0162607,

NONCODE: NONHSAT013369.2,

URS0000D77F73_9606 lncRNA 3617 1

RefSeq: NR_158661,

URS0000EF3406_9606 lncRNA 3593 1

Ensembl: ENST00000651763 (view in UCSC) ,

URS0000EF3C6A_9606 lncRNA 3519 1

Ensembl: ENST00000651208 (view in UCSC) ,

TIMM23B-AGAP6 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TIMM23B-AGAP6 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for TIMM23B-AGAP6 Gene

No ASD Table

Relevant External Links for TIMM23B-AGAP6 Gene

GeneLoc Exon Structure for
TIMM23B-AGAP6

Expression for TIMM23B-AGAP6 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TIMM23B-AGAP6 Gene

Orthologs for TIMM23B-AGAP6 Gene

Evolution for TIMM23B-AGAP6 Gene

ENSEMBL:
Gene Tree for TIMM23B-AGAP6 (if available)
TreeFam:
Gene Tree for TIMM23B-AGAP6 (if available)

No data available for Orthologs for TIMM23B-AGAP6 Gene

Paralogs for TIMM23B-AGAP6 Gene

No data available for Paralogs for TIMM23B-AGAP6 Gene

Variants for TIMM23B-AGAP6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TIMM23B-AGAP6 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
769369 Benign: not provided 50,008,914(+) CAA/C FRAMESHIFT_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for TIMM23B-AGAP6 Gene

Additional Variant Information for TIMM23B-AGAP6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TIMM23B-AGAP6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TIMM23B-AGAP6 Gene

Disorders for TIMM23B-AGAP6 Gene

No disorders were found for TIMM23B-AGAP6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TIMM23B-AGAP6 Gene

Publications for TIMM23B-AGAP6 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for TIMM23B-AGAP6 Gene

Sources for TIMM23B-AGAP6 Gene