Free for academic non-profit institutions. Other users need a Commercial license
Aliases for TIMM21 Gene
Aliases for TIMM21 Gene
External Ids for TIMM21 Gene
- HGNC: 25010
- NCBI Entrez Gene: 29090
- Ensembl: ENSG00000075336
- OMIM®: 615180
- UniProtKB/Swiss-Prot: Q9BVV7
Previous HGNC Symbols for TIMM21 Gene
- C18orf55
Previous GeneCards Identifiers for TIMM21 Gene
- GC18P071816
Summaries for TIMM21 Gene
GeneCards Summary for TIMM21 Gene
TIMM21 (Translocase Of Inner Mitochondrial Membrane 21) is a Protein Coding gene. Diseases associated with TIMM21 include Neuropathy, Ataxia, And Retinitis Pigmentosa. Among its related pathways are Metabolism of proteins and Mitochondrial protein import.
UniProtKB/Swiss-Prot Summary for TIMM21 Gene
-
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Additional gene information for TIMM21 Gene
- HGNC (25010)
- NCBI Entrez Gene (29090)
- Ensembl (ENSG00000075336)
- OMIM® (615180)
- UniProtKB/Swiss-Prot (Q9BVV7)
- Open Targets Platform(ENSG00000075336)
- Search for TIMM21 at DataMed
- Search for TIMM21 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TIMM21 Gene
Genomics for TIMM21 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TIMM21 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TIMM21 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TIMM21
Genomic Locations for TIMM21 Gene
Latest Assembly
- chr18:74,148,517-74,160,531
- (GRCh38/hg38)
- Size:
- 12,015 bases
- Orientation:
- Plus strand
Previous Assembly
- chr18:71,815,758-71,827,766
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 12,009 bases
- Orientation:
- Plus strand
- chr18:71,815,746-71,826,197
- (GRCh37/hg19 by Ensembl)
- Size:
- 10,452 bases
- Orientation:
- Plus strand
Genomic View for TIMM21 Gene
Genes around TIMM21 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q22.3 by HGNC
- 18q22.3 by Entrez Gene
- 18q22.3 by Ensembl
TIMM21 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TIMM21 Gene
Proteins for TIMM21 Gene
-
Protein details for TIMM21 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BVV7-TIM21_HUMAN
- Recommended name:
- Mitochondrial import inner membrane translocase subunit Tim21
- Protein Accession:
- Q9BVV7
- Q9P010
Protein attributes for TIMM21 Gene
- Size:
- 248 amino acids
- Molecular mass:
- 28202 Da
- Quaternary structure:
-
- Component of the TIM23 complex. Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, the core components of this complex being COA3/MITRAC12 and COX14 (Probable) (PubMed:23260140). Interacts with COA3 AND MT-CO1/COX1 (PubMed:26321642).
Protein Expression for TIMM21 Gene
Post-translational modifications for TIMM21 Gene
Other Protein References for TIMM21 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for TIMM21
- Invitrogen Antibodies for TIMM21 (AFLGC-TIMM21)
-
Biorbyt antibodies for TIMM21
- Sino Biological Antibodies for TIMM21
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TIMM21
- Origene Custom Protein Services for TIMM21
- antibodies-online: Show 3 available C18orf55 Proteins ranked by validation data
- Compare Top C18orf55 Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for TIMM21 Gene
Domains & Families for TIMM21 Gene
Gene Families for TIMM21 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for TIMM21 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for TIMM21 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA, FLJ94576 (A8K1K8_HUMAN)
- TIM21-like protein, mitochondrial (TI21L_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BVV7- Family:
-
- Belongs to the TIM21 family.
Function for TIMM21 Gene
Molecular function for TIMM21 Gene
- UniProtKB/Swiss-Prot Function:
- Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Phenotypes From GWAS Catalog for TIMM21 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0005515 | protein binding | IPI | 23260140 |
Phenotypes for TIMM21 Gene
- GenomeRNAi human phenotypes for TIMM21:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TIMM21 - Starting at $85 >
- * TIMM21 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TIMM21
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TIMM21
-
Santa Cruz Biotechnology (SCBT) CRISPR for TIMM21
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TIMM21
- Browse OriGene Inhibitory RNA Products For TIMM21
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TIMM21
Clone products for research
- Applied Biological Materials (abm): Clones for TIMM21 - Starting at $45 >
- * TIMM21 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TIMM21
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TIMM21
Cell Lines for research
-
Horizon Cell Lines for TIMM21
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TIMM21 Gene
Localization for TIMM21 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TIMM21 Gene
- Mitochondrion membrane. Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| peroxisome | 1 |
| cytosol | 1 |
| golgi apparatus | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005744 | TIM23 mitochondrial import inner membrane translocase complex | IEA,IDA | 23260140 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0031966 | mitochondrial membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TIMM21 Gene
Pathways & Interactions for TIMM21 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Mitochondrial protein import | ||
Pathways by source for TIMM21 Gene
2 Reactome pathways for TIMM21 Gene
Interacting Proteins for TIMM21 Gene
Selected Interacting proteins:
Q9BVV7-TIM21_HUMAN
ENSP00000169551
for TIMM21 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TIMM21
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015031 | protein transport | IEA | -- |
| GO:0030150 | protein import into mitochondrial matrix | IEA,IMP | 23260140 |
| GO:0032981 | mitochondrial respiratory chain complex I assembly | IMP | 23260140 |
| GO:0033617 | mitochondrial respiratory chain complex IV assembly | IMP | 23260140 |
No data available for SIGNOR curated interactions for TIMM21 Gene
Transcripts for TIMM21 Gene
mRNA/cDNA for TIMM21 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000169551 3084 nts (view in UCSC)
- ENST00000577952 858 nts (view in UCSC)
- ENST00000579071 821 nts (view in UCSC)
- ENST00000580087 2524 nts (view in UCSC)
- ENST00000581467 579 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TIMM21 - Starting at $85 >
- * TIMM21 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TIMM21
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TIMM21
-
Santa Cruz Biotechnology (SCBT) CRISPR for TIMM21
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TIMM21
- Browse OriGene Inhibitory RNA Products For TIMM21
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TIMM21
Clone products for research
- Applied Biological Materials (abm): Clones for TIMM21 - Starting at $45 >
- * TIMM21 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TIMM21
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TIMM21
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||
| SP5: |
Relevant External Links for TIMM21 Gene
- GeneLoc Exon Structure for
- TIMM21
Expression for TIMM21 Gene
This gene is overexpressed in Bone (26.7) and Peripheral blood mononuclear cells (11.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TIMM21 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TIMM21
SOURCE GeneReport for Unigene cluster for TIMM21 Gene:
Hs.532835Evidence on tissue expression from TISSUES for TIMM21 Gene
- Blood(4.3)
- Nervous system(2.5)
- Muscle(2.1)
Primer products for research
-
OriGene qPCR primer pairs for TIMM21
-
OriGene qPCR primer pairs and template standards for TIMM21
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TIMM21 Gene
Orthologs for TIMM21 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TIMM21 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TIMM21 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TIMM21 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Timm21 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Timm21 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | TIMM21 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | C18ORF55 30 |
|
||
| TIMM21 31 |
|
OneToOne | |||
| Lizard (Anolis carolinensis) |
Reptilia | TIMM21 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | timm21 30 |
|
||
| Str.5951 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.10854 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | si:dkey-118j18.1 30 |
|
||
| TIMM21 31 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008572 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG7382 30 31 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | F56B3.11 30 31 |
|
OneToOne |
- Species where no ortholog for TIMM21 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TIMM21 Gene
- ENSEMBL:
- Gene Tree for TIMM21 (if available)
- TreeFam:
- Gene Tree for TIMM21 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TIMM21: view image
Paralogs for TIMM21 Gene
(1) SIMAP similar genes for TIMM21 Gene using alignment to 3 proteins:
- TIM21_HUMAN
- J3KRJ3_HUMAN
- J3QRI1_HUMAN
No data available for Paralogs for TIMM21 Gene
Variants for TIMM21 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TIMM21 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3737512 | - |
p.Gly79Ser |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3400n100 | CNV | gain | 25217958 |
| esv27743 | CNV | loss | 19812545 |
| esv3643105 | CNV | loss | 21293372 |
| nsv577650 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
53.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.57;
65.08% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TIMM21 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TIMM21
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TIMM21 Gene
Disorders for TIMM21 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neuropathy, ataxia, and retinitis pigmentosa |
|
|
Search TIMM21 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TIMM21
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TIMM21 Gene
Publications for TIMM21 Gene
- MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation. (PMID: 23260140) Mick DU … Rehling P (Cell 2012) 2 3 4
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang QH … Chen Z (Genome research 2000) 2 3 4
- MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly. (PMID: 26321642) Dennerlein S … Rehling P (Cell reports 2015) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
ExternalLinks
Products for TIMM21 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TIMM21
- Origene Custom Protein Services for TIMM21
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TIMM21
- Browse OriGene Inhibitory RNA Products For TIMM21
- OriGene qPCR primer pairs for TIMM21
- OriGene qPCR primer pairs and template standards for TIMM21
- OriGene CRISPR knockouts for TIMM21
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TIMM21
- Sino Biological Human cDNA Clone for TIMM21
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for TIMM21
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TIMM21
- Novus Biologicals proteins and lysates for TIMM21
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for TIMM21 (AFLGC-TIMM21)
- VectorBuilder Custom and pre-made DNA vectors for TIMM21 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TIMM21 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TIMM21 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TIMM21 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TIMM21
- antibodies-online: Show 17 available C18orf55 Antibodies ranked by validation data
- Compare Top C18orf55 Antibodies
- antibodies-online: Search results for available C18orf55 related products ranked by validation data
- antibodies-online: Show 3 available C18orf55 Proteins ranked by validation data
- Compare Top C18orf55 Proteins
- Quality Products:
- Horizon Cell Lines for TIMM21
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TIMM21
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TIMM21
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TIMM21
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TIMM21
- Biorbyt antibodies for TIMM21
Sources for TIMM21 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB