Aliases for THY1 Gene
Aliases for THY1 Gene
External Ids for THY1 Gene
- HGNC: 11801
- Entrez Gene: 7070
- Ensembl: ENSG00000154096
- OMIM: 188230
- UniProtKB: P04216
Previous GeneCards Identifiers for THY1 Gene
- GC11M121288
- GC11M120800
- GC11M119322
- GC11M118826
- GC11M118795
- GC11M119288
- GC11M115230
Summaries for THY1 Gene
-
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
GeneCards Summary for THY1 Gene
THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Thymoma and Nasopharyngeal Carcinoma. Among its related pathways are Metabolism of proteins and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator activity.
UniProtKB/Swiss-Prot for THY1 Gene
-
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Additional gene information for THY1 Gene
- Monarch Initiative
- Search for THY1 at DataMed
- Search for THY1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for THY1 Gene
Genomics for THY1 Gene
GeneHancer (GH) Regulatory Elements for THY1 Gene
Promoters and enhancers for THY1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11I119421 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE dbSUPER | 576 | +2.3 | 2316 | 2.3 | SRF MXI1 SMAD5 BACH1 SIN3A ETS1 RELA POLR2A POLR3A IKZF1 | THY1 HINFP ENSG00000263873 USP2-AS1 | |
| GH11I119423 | Enhancer | 0.6 | ENCODE dbSUPER | 570 | +0.2 | 210 | 1.8 | SMAD5 POLR3A POLR2A | THY1 USP2 USP2-AS1 ENSG00000254740 HINFP C1QTNF5 MFRP ENSG00000263873 | |
| GH11I119426 | Enhancer | 0.4 | ENCODE | 570 | -1.6 | -1610 | 0.7 | MITF USF1 | THY1 USP2 USP2-AS1 ENSG00000254740 C1QTNF5 MFRP GC11M119445 | |
| GH11I119425 | Enhancer | 0.4 | ENCODE | 550.8 | -1.1 | -1062 | 0.2 | MITF USF1 | THY1 USP2 USP2-AS1 ENSG00000254740 C1QTNF5 MFRP GC11M119445 | |
| GH11I119374 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE dbSUPER | 22 | +48.0 | 47971 | 5.5 | PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF143 SP5 NFYC | USP2 THY1 MFRP C1QTNF5 ENSG00000254740 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around THY1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for THY1 Gene
Genomic Locations for THY1 Gene
- chr11:119,417,378-119,424,985
- (GRCh38/hg38)
- Size:
- 7,608 bases
- Orientation:
- Minus strand
- chr11:119,288,090-119,295,695
- (GRCh37/hg19)
Genomic View for THY1 Gene
Genes around THY1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q23.3 by Ensembl
- 11q23.3 by Entrez Gene
- 11q23.3 by HGNC
THY1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for THY1 Gene
Proteins for THY1 Gene
-
Protein details for THY1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P04216-THY1_HUMAN
- Recommended name:
- Thy-1 membrane glycoprotein
- Protein Accession:
- P04216
- Q16008
- Q9NSP1
Protein attributes for THY1 Gene
- Size:
- 161 amino acids
- Molecular mass:
- 17935 Da
- Quaternary structure:
- No Data Available
Protein Expression for THY1 Gene
Post-translational modifications for THY1 Gene
- Glycosylation at posLast=4242, isoforms=79, isoforms=119, and posLast=139139
Other Protein References for THY1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for THY1 (CD90/Thy1)
- Cell Signaling Technology (CST) Antibodies for THY1 (THY1)
- Novus Biologicals Antibodies for THY1
-
Abcam antibodies for THY1
-
Cloud-Clone Corp. Antibodies for THY1
- Invitrogen Antibodies for THY1
- antibodies-online: Search results for 754 available CD90 Antibodies ranked by validation data
- Compare Top CD90 Antibodies
-
Recommended
- 2 ISt Antibodies (anti-mouse)
- 2 IP Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 2 IF (p) Antibodies (anti-mouse)
- 2 IC Antibodies (anti-mouse)
- 3 IHC (zinc) Antibodies (anti-mouse)
- 3 IF Antibodies (anti-mouse)
- 4 in vitro Antibodies (anti-mouse)
- 6 ICC Antibodies (anti-mouse)
- 8 CyTox Antibodies (anti-mouse)
- 14 IHC Antibodies (anti-mouse)
- 43 IHC (fro) Antibodies (anti-mouse)
- 66 WB Antibodies (anti-mouse)
- 158 FACS Antibodies (anti-mouse)
- 1 IP Antibody (anti-rat)
- 1 IHC (zinc) Antibody (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 1 IF Antibody (anti-rat)
- 2 IF (p) Antibodies (anti-rat)
- 3 IHC Antibodies (anti-rat)
- 4 CyTox Antibodies (anti-rat)
- 20 IHC (fro) Antibodies (anti-rat)
- 52 WB Antibodies (anti-rat)
- 55 FACS Antibodies (anti-rat)
- 1 EIA Antibody (anti-human)
- 2 ICFC Antibodies (anti-human)
- 7 IHC (p) Antibodies (anti-human)
- 9 IF Antibodies (anti-human)
- 14 IF (p) Antibodies (anti-human)
- 15 IHC Antibodies (anti-human)
- 17 IHC (fro) Antibodies (anti-human)
- 30 IP Antibodies (anti-human)
- 106 FACS Antibodies (anti-human)
- 167 WB Antibodies (anti-human)
- GeneTex THY1 antibody for THY1
-
Custom Antibody ServicesProSci Antibodies for THY1
-
Santa Cruz Biotechnology (SCBT) Antibodies for THY1
- Sino Biological Antibodies for THY1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for THY1
- Origene Custom Protein Services for THY1
- Sino Biological Recombinant Proteins for THY1
- Sino Biological Cell Lysates for THY1
- ProSpec Recombinant Proteins for THY1
-
Cloud-Clone Corp. Proteins for THY1
- Search GeneTex for Proteins for THY1
-
ProSci Proteins for THY1
-
Abcam proteins for THY1
Assay Products
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for THY1 (CD90/Thy1)
-
Cloud-Clone Corp. Assay Kits for THY1
No data available for DME Specific Peptides for THY1 Gene
Domains & Families for THY1 Gene
Gene Families for THY1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- CD markers
- Plasma proteins
- Predicted membrane proteins
- Predicted secreted proteins
Protein Domains for THY1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for THY1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for THY1 Gene
Function for THY1 Gene
Molecular function for THY1 Gene
- GENATLAS Biochemistry:
- Thy-1 cell surface antigen
- UniProtKB/Swiss-Prot Function:
- May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Phenotypes From GWAS Catalog for THY1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | ISS,IBA | -- |
| GO:0005178 | integrin binding | IEA,IPI | 15004192 |
| GO:0005515 | protein binding | IPI | 7513706 |
| GO:0019899 | enzyme binding | IEA | -- |
| GO:0019901 | protein kinase binding | IBA | -- |
Phenotypes for THY1 Gene
- MGI mutant phenotypes for THY1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for THY1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for THY1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for THY1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for THY1 gene
- Search ViGene Biosciences for THY1
CRISPR Products
-
OriGene CRISPR knockouts for THY1
- genomics-online: gRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- Applied Biological Materials CRISPR for THY1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for THY1
- GenScript: Design CRISPR guide RNA sequences for THY1
miRNA for THY1 Gene
- miRTarBase miRNAs that target THY1
-
- hsa-mir-1-3p (MIRT024103)
- hsa-mir-1228-5p (MIRT490392)
- hsa-mir-139-3p (MIRT490393)
- hsa-mir-4781-5p (MIRT490394)
- hsa-mir-4706 (MIRT490395)
- hsa-mir-519d-3p (MIRT490396)
- hsa-mir-6836-3p (MIRT490397)
- hsa-mir-6825-5p (MIRT490398)
- hsa-mir-6729-5p (MIRT490399)
- hsa-mir-4649-5p (MIRT490400)
- hsa-mir-7106-5p (MIRT490401)
- hsa-mir-766-5p (MIRT490402)
- hsa-mir-6829-3p (MIRT490403)
- hsa-mir-6778-3p (MIRT490404)
- hsa-mir-6791-3p (MIRT490405)
- hsa-mir-4685-3p (MIRT490406)
- hsa-mir-4287 (MIRT490407)
- hsa-mir-519e-3p (MIRT490408)
- hsa-mir-515-3p (MIRT490409)
- hsa-mir-33b-3p (MIRT490410)
- hsa-mir-1287-5p (MIRT737076)
- hsa-mir-3135b (MIRT740139)
- hsa-mir-3692-5p (MIRT742537)
- hsa-mir-4269 (MIRT743543)
- hsa-mir-4514 (MIRT745729)
- hsa-mir-4692 (MIRT747135)
- hsa-mir-486-3p (MIRT749135)
- hsa-mir-6715b-5p (MIRT753697)
- hsa-mir-6721-5p (MIRT753841)
- hsa-mir-6808-5p (MIRT756608)
- hsa-mir-6893-5p (MIRT758753)
- hsa-mir-940 (MIRT760849)
miRNA Products
- Search ViGene Biosciences for THY1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for THY1
- Browse OriGene Inhibitory RNA Products For THY1
- genomics-online: shRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for THY1 gene
Clone Products
- Sino Biological Human cDNA Clone for THY1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for THY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THY1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for THY1
- Applied Biological Materials Clones for THY1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for THY1
-
ViGene Biosciences adenoviral particle packaged cDNA for THY1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for THY1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for THY1 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for THY1 Gene
Localization for THY1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for THY1 Gene
- Cell membrane; Lipid-anchor, GPI-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| cytoskeleton | 3 |
| cytosol | 3 |
| nucleus | 2 |
| mitochondrion | 1 |
| lysosome | 1 |
- Nucleus (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005783 | endoplasmic reticulum | IDA | -- |
| GO:0005829 | cytosol | IEA | -- |
| GO:0005886 | plasma membrane | NAS,TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 2864289 |
Pathways & Interactions for THY1 Gene
Pathways by source for THY1 Gene
1 Cell Signaling Technology pathway for THY1 Gene
3 BioSystems pathways for THY1 Gene
3 Reactome pathways for THY1 Gene
1 KEGG pathway for THY1 Gene
4 R&D Systems pathways for THY1 Gene
1 Qiagen pathway for THY1 Gene
Interacting Proteins for THY1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001525 | angiogenesis | ISS | -- |
| GO:0001952 | regulation of cell-matrix adhesion | IMP | 9749990 |
| GO:0002693 | positive regulation of cellular extravasation | IDA | 15004192 |
| GO:0006469 | negative regulation of protein kinase activity | ISS | -- |
| GO:0006501 | C-terminal protein lipidation | TAS | -- |
No data available for SIGNOR curated interactions for THY1 Gene
Transcripts for THY1 Gene
mRNA/cDNA for THY1 Gene
- (3) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (719) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for THY1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for THY1
- genomics-online: gRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- Applied Biological Materials CRISPR for THY1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for THY1
- GenScript: Design CRISPR guide RNA sequences for THY1
miRNA Products
- Search ViGene Biosciences for THY1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for THY1
- Browse OriGene Inhibitory RNA Products For THY1
- genomics-online: shRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for THY1 gene
Clone Products
- Sino Biological Human cDNA Clone for THY1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for THY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THY1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for THY1
- Applied Biological Materials Clones for THY1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | · | 9c |
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| SP7: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP12: | - | - |
Expression for THY1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Zeugopod Periosteum
- Mesenchymal Stem Cells Cord Blood
- Mesenchymal Stem Cells Microvessels
- Bone Marrow Stromal Cells Pelvic Girdle
- Adventitial Reticular Cells Bone Marrow
-
Bone (Muscoskeletal System)
- Chondrocytes Zeugopod Epiphyseal End
- Mesenchymal Stem Cells Zeugopod Periosteum
- Adventitial Reticular Cells Bone Marrow
- Bone Marrow Stromal Cells Bone Marrow
- Bone marrow-derived mesenchymal stromal cells
- Umbilical Cord (Extraembryonic Tissues)
-
Blood (Hematopoietic System)
- Mesenchymal Stem Cells Cord Blood
- Basophils Peripheral Blood
- B-cell Progenitor Cells Peripheral Blood
- Hematopoietic Stem Cells Liver Bud
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
-
Adipose (Muscoskeletal System)
- Stromal Cells Subcutaneous White Adipose
- Mesenchymal Stem Cells Subcutaneous White Adipose
- Adipose-derived stem cells (Adipoplus)
- Adipose-derived mesenchymal stem cells combined with allograft bone (AlloStem)
- Adipose-derived stromal cells
-
Fibroblasts
- Dermal Fibroblasts Ventral Dermis
- Dermal Fibroblasts Cranial Dermis
- Cardiac Fibroblasts Myocardium
- Dermal Fibroblasts Dorsal Dermis
- Fibroblasts (family)
- Placenta (Extraembryonic Tissues)
- Tooth (Integumentary System)
-
Dermis (Integumentary System)
- Dermal Fibroblasts Ventral Dermis
- Dermal Fibroblasts Cranial Dermis
- Dermal Fibroblasts Dorsal Dermis
- Collagen-producing cells derived from skin fibroblasts
- SR1 Dermal Fibroblasts
- Inner Cell Mass (Early Embryonic Tissues)
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
- nGnG Amacrine Cells Inner Nuclear Layer
- Limbal epithelial stem cells
- Limbal epithelial stem cells (family)
- Human corneal endothelial cells
- Brain (Nervous System)
- NULL (Nervous System)
- Endothelium (Cardiovascular System)
- Heart (Cardiovascular System)
-
Epithelial Cells
- Basal Keratinocytes Embryonic Epidermis
- Amniotic Epithelial Cells Amniotic Membrane
- Limbal epithelial stem cells
- Limbal epithelial stem cells (family)
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
- nGnG Amacrine Cells Inner Nuclear Layer
- Neural stem/progenitor cells (family)
-
Cartilage (Muscoskeletal System)
- Chondrocytes Zeugopod Epiphyseal End
- Mesenchymal Stem Cells Zeugopod Periosteum
- Bone Marrow Stromal Cells Bone Marrow
- Liver (Hepatobiliary System)
-
Hair
- Basal Keratinocytes Embryonic Epidermis
- Hair follicle-derived mesenchymal stem cells
- Hair follicle stem cells
-
Amnion (Extraembryonic Tissues)
- Mesenchymal Stem Cells Amniotic Fluid
- Amniotic Epithelial Cells Amniotic Membrane
- Neural Crest (Gastrulation Derivatives)
-
Limb (Muscoskeletal System)
- Bone Marrow Stromal Cells Pelvic Girdle
-
Chorion (Extraembryonic Tissues)
- Chorionic Mesenchymal Stromal Cells Chorionic Villus
-
Epidermis (Integumentary System)
- Basal Keratinocytes Embryonic Epidermis
- Neural Tube (Nervous System)
- Lower Urinary Tract (Urinary System)
- Kidney (Urinary System)
- Thymus (Hematopoietic System)
- Uterus (Reproductive System)
- Lung (Respiratory System)
- Tendon & Ligament (Muscoskeletal System)
- Lymph (Cardiovascular System)
- Smooth Muscle (Muscoskeletal System)
- Intestine
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for THY1 Gene
This gene is overexpressed in Brain - Cortex (x5.3), Brain - Frontal Cortex (BA9) (x4.8), and Brain - Anterior cingulate cortex (BA24) (x4.3).
This gene is overexpressed in Frontal cortex (17.5), Brain (11.3), and Cerebrospinal fluid (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for THY1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of THY1 Gene:
THY1SOURCE GeneReport for Unigene cluster for THY1 Gene:
Hs.644697Evidence on tissue expression from TISSUES for THY1 Gene
- Nervous system(5)
- Eye(4.8)
- Liver(4.5)
- Kidney(4.2)
- Lung(3.9)
- Skin(3.8)
- Blood(3.3)
- Heart(3.3)
- Spleen(3.3)
- Bone(3.2)
- Bone marrow(3.1)
- Lymph node(3)
- Intestine(2.8)
- Muscle(2.7)
- Pancreas(2.6)
- Thyroid gland(2.2)
- Gall bladder(2.1)
Primer Products
-
OriGene qPCR primer pairs for THY1
-
OriGene qPCR primer pairs and template standards for THY1
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for THY1 Gene
Orthologs for THY1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | THY1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | THY1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | THY1 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Thy1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Thy1 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | THY1 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | THY1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | THY1 33 |
|
||
| gga-mir-1466 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | THY1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | thy1 33 |
|
- Species where no ortholog for THY1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for THY1 Gene
No data available for Paralogs for THY1 Gene
Variants for THY1 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000094024 | -- | 119,420,751(-) | G/A | intron_variant | |
| rs1000641271 | -- | 119,421,637(-) | C/T | 5_prime_UTR_variant, intron_variant | |
| rs1000953985 | -- | 119,425,655(-) | G/A/C | upstream_transcript_variant | |
| rs1001205 | -- | 119,422,002(-) | T/C | 5_prime_UTR_variant, intron_variant | |
| rs1001206595 | -- | 119,421,769(-) | A/G | 5_prime_UTR_variant, intron_variant |
Residual Variation Intolerance Score:
54.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.37;
8.18% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for THY1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- THY1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for THY1 Gene
Disorders for THY1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| thymoma |
|
|
| nasopharyngeal carcinoma |
|
|
| warthin tumor |
|
|
| gerstmann-straussler disease |
|
|
| murray valley encephalitis |
|
|
Search THY1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for THY1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Tumor Gene Database
- (TGDB)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for THY1 Gene
Publications for THY1 Gene
- Non-HLA genetic factors and insulin dependent diabetes mellitus in the Japanese: TCRA, TCRB and TCRG, INS, THY1, CD3D and ETS1. (PMID: 1982251) Aparicio JM … Yoshiki T (Disease markers 1990) 3 22 44 58
- The human Thy-1 gene: structure and chromosomal location. (PMID: 2864690) Seki T … Silver J (Proceedings of the National Academy of Sciences of the United States of America 1985) 2 3 4 58
- Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study. (PMID: 20478055) Brophy K … McManus R (BMC medical genetics 2010) 3 44 58
- A decreased positivity for CD90 on human mesenchymal stromal cells (MSCs) is associated with a loss of immunosuppressive activity by MSCs. (PMID: 18985728) Campioni D … Lanza F (Cytometry. Part B, Clinical cytometry 2009) 3 22 58
- Evidence for enhanced Thy-1 (CD90) expression in orbital fibroblasts of patients with Graves' ophthalmopathy. (PMID: 18976167) Khoo TK … Bahn RS (Thyroid : official journal of the American Thyroid Association 2008) 3 22 58
Products for THY1 Gene
- R&D Systems Antibodies for THY1 (CD90/Thy1)
- Browse R&D Systems for Human Recombinant Proteins
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for THY1 (CD90/Thy1)
- Browse Human Proteins and Enzymes
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- Custom Antibody ServicesOriGene Antibodies for THY1
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for THY1
- Origene Custom Protein Services for THY1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for THY1
- Browse OriGene Inhibitory RNA Products For THY1
- OriGene qPCR primer pairs and template standards for THY1
- OriGene qPCR primer pairs for THY1
- OriGene CRISPR knockouts for THY1
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For THY1
- GenScript: Next-day shipping of latest version cDNA ORF clones for THY1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for THY1
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- GenScript Custom Peptide Services for THY1
- Cell Signaling Technology (CST) Antibodies for THY1 (THY1)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for THY1
- Sino Biological Cell Lysates for THY1
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- Novus Biologicals Antibodies for THY1
- Novus Biologicals lysates and proteins for THY1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
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- Browse ELISA Kits
- Abcam antibodies for THY1
- Abcam proteins for THY1
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for THY1
- Cloud-Clone Corp. Antibodies for THY1
- Cloud-Clone Corp. Proteins for THY1
- Cloud-Clone Corp. Assay Kits for THY1
- Browse Knockouts at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for THY1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for THY1
- VectorBuilder custom plasmid, inducible vectors for THY1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for THY1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for THY1
- antibodies-online: Search results for 754 available CD90 Antibodies ranked by validation data
- Compare Top CD90 Antibodies
- Recommended
- 167 WB Antibodies (anti-human)
- 106 FACS Antibodies (anti-human)
- 30 IP Antibodies (anti-human)
- 17 IHC (fro) Antibodies (anti-human)
- 15 IHC Antibodies (anti-human)
- 14 IF (p) Antibodies (anti-human)
- 9 IF Antibodies (anti-human)
- 7 IHC (p) Antibodies (anti-human)
- 2 ICFC Antibodies (anti-human)
- 1 EIA Antibody (anti-human)
- 55 FACS Antibodies (anti-rat)
- 52 WB Antibodies (anti-rat)
- 20 IHC (fro) Antibodies (anti-rat)
- 4 CyTox Antibodies (anti-rat)
- 3 IHC Antibodies (anti-rat)
- 2 IF (p) Antibodies (anti-rat)
- 1 IF Antibody (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 1 IHC (zinc) Antibody (anti-rat)
- 1 IP Antibody (anti-rat)
- 158 FACS Antibodies (anti-mouse)
- 66 WB Antibodies (anti-mouse)
- 43 IHC (fro) Antibodies (anti-mouse)
- 14 IHC Antibodies (anti-mouse)
- 8 CyTox Antibodies (anti-mouse)
- 6 ICC Antibodies (anti-mouse)
- 4 in vitro Antibodies (anti-mouse)
- 3 IF Antibodies (anti-mouse)
- 3 IHC (zinc) Antibodies (anti-mouse)
- 2 IC Antibodies (anti-mouse)
- 2 IF (p) Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 2 IP Antibodies (anti-mouse)
- 2 ISt Antibodies (anti-mouse)
- antibodies-online: Search results for 21 available CD90 Elisa Kits ranked by validation data
- Compare Top CD90 Elisa Kits
- antibodies-online: Search results for 17 available CD90 Proteins ranked by validation data
- Compare Top CD90 Proteins
- GeneTex THY1 antibody for THY1
- Search GeneTex for Proteins for THY1
- ViGene Biosciences adenoviral particle packaged cDNA for THY1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for THY1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for THY1 gene
- Search ViGene Biosciences for THY1
- Santa Cruz Biotechnology (SCBT) Antibodies for THY1
- Search Santa Cruz Biotechnology (SCBT) for THY1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for THY1
- Custom Antibody ServicesProSci Antibodies for THY1
- ProSci Proteins for THY1
- Horizon Cell Lines for THY1
- genomics-online: cdna clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- orf clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- genomics-online: gRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- genomics-online: primer clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
- genomics-online: shRNA clones - Search results for 160 available CD90 gene related products
- Overview of 160 available CD90 gene related products
Sources for THY1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
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- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
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- (114) diseasecard
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- (133) ENCODE
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- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
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- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew