External Ids for THBS3 Gene
Previous GeneCards Identifiers for THBS3 Gene
The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011]
GeneCards Summary for THBS3 Gene
THBS3 (Thrombospondin 3) is a Protein Coding gene. Diseases associated with THBS3 include Pregnancy Adenoma and Pseudoachondroplasia. Among its related pathways are Focal Adhesion and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include calcium ion binding and heparin binding. An important paralog of this gene is THBS4.
UniProtKB/Swiss-Prot Summary for THBS3 Gene
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.