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The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008] See more...
Aliases for THAP11 Gene
Aliases for THAP11 Gene
External Ids for THAP11 Gene
- HGNC: 23194
- NCBI Entrez Gene: 57215
- Ensembl: ENSG00000168286
- OMIM®: 609119
- UniProtKB/Swiss-Prot: Q96EK4
Previous GeneCards Identifiers for THAP11 Gene
- GC16U900023
- GC16P067652
- GC16P066433
- GC16P067876
- GC16P053749
Summaries for THAP11 Gene
-
The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008]
GeneCards Summary for THAP11 Gene
THAP11 (THAP Domain Containing 11) is a Protein Coding gene. Diseases associated with THAP11 include Disorders Of Intracellular Cobalamin Metabolism and Methylmalonic Acidemia And Homocysteinemia, Cblx Type. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.
UniProtKB/Swiss-Prot Summary for THAP11 Gene
-
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
Additional gene information for THAP11 Gene
- HGNC (23194)
- NCBI Entrez Gene (57215)
- Ensembl (ENSG00000168286)
- OMIM® (609119)
- UniProtKB/Swiss-Prot (Q96EK4)
- Open Targets Platform(ENSG00000168286)
- Monarch Initiative
- Search for THAP11 at DataMed
- Search for THAP11 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for THAP11 Gene
Genomics for THAP11 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for THAP11 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around THAP11 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for THAP11
- Top Transcription factor binding sites by QIAGEN in the THAP11 gene promoter:
-
- ATF-2
- CRE-BP1
- Egr-4
- GATA-2
- MyoD
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
Genomic Locations for THAP11 Gene
Latest Assembly
- chr16:67,842,320-67,844,195
- (GRCh38/hg38)
- Size:
- 1,876 bases
- Orientation:
- Plus strand
Previous Assembly
- chr16:67,876,223-67,878,098
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 1,876 bases
- Orientation:
- Plus strand
- chr16:67,876,213-67,878,097
- (GRCh37/hg19 by Ensembl)
- Size:
- 1,885 bases
- Orientation:
- Plus strand
Genomic View for THAP11 Gene
Genes around THAP11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q22.1 by HGNC
- 16q22.1 by Entrez Gene
- 16q22.1 by Ensembl
THAP11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for THAP11 Gene
Proteins for THAP11 Gene
-
Protein details for THAP11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96EK4-THA11_HUMAN
- Recommended name:
- THAP domain-containing protein 11
- Protein Accession:
- Q96EK4
- A4UCT5
- A8K002
- O94795
Protein attributes for THAP11 Gene
- Size:
- 314 amino acids
- Molecular mass:
- 34455 Da
- Quaternary structure:
-
- Interacts (via coiled coil domain) with HCFC1.
Protein Expression for THAP11 Gene
Post-translational modifications for THAP11 Gene
Other Protein References for THAP11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for THAP11
- Novus Biologicals Antibodies for THAP11
-
Abcam antibodies for THAP11
- Invitrogen Antibodies for THAP11 (AFLGC-THAP11)
-
Custom Antibody ServicesProSci Antibodies for THAP11
-
Santa Cruz Biotechnology (SCBT) Antibodies for THAP11
- Sino Biological Antibodies for THAP11
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for THAP11
- Origene Custom Protein Services for THAP11
- ProSpec Recombinant Proteins for THAP11
-
Abcam proteins for THAP11
Assay products for research
- RayBiotech Custom Human THAP11 ELISA
No data available for DME Specific Peptides for THAP11 Gene
Domains & Families for THAP11 Gene
Gene Families for THAP11 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for THAP11 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for THAP11 Gene
- GenScript: Design optimal peptide antigens:
-
- THAP domain containing 11 (B5APZ3_HUMAN)
- THAP domain-containing protein 11 (THA11_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96EK4- Family:
-
- Belongs to the THAP11 family.
Function for THAP11 Gene
Molecular function for THAP11 Gene
- UniProtKB/Swiss-Prot Function:
- Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
Phenotypes From GWAS Catalog for THAP11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | 19008924 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IDA | 19008924 |
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003677 | DNA binding | IEA,IDA | 23306615 |
Phenotypes for THAP11 Gene
- MGI mutant phenotypes for THAP11:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for THAP11:
Animal Models for THAP11 Gene
- MGI Knock Outs for THAP11:
-
- Thap11 Thap11<tm1.1Tpz>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for THAP11 - Starting at $85 >
- * THAP11 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for THAP11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for THAP11
-
Santa Cruz Biotechnology (SCBT) CRISPR for THAP11
Targeted motifs for THAP11 Gene
HOMER Transcription Factor Regulatory Elements motif THAP11
- Consensus sequence: RACTACAACTCCCAGVAKGC Submotif: canonical Cell Type: ES GEO ID: GSE51522
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for THAP11
- Browse OriGene Inhibitory RNA Products For THAP11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for THAP11
Clone products for research
- Applied Biological Materials (abm): Clones for THAP11 - Starting at $45 >
- * THAP11 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for THAP11
- Addgene plasmids for THAP11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for THAP11
Cell Lines for research
-
Horizon Cell Lines for THAP11
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA and Transcription Factor Targets for THAP11 Gene
Localization for THAP11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for THAP11 Gene
- Nucleus. Cytoplasm. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 4 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
- Nucleoplasm (3)
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | ISA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IBA,IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for THAP11 Gene
Interacting Proteins for THAP11 Gene
Selected Interacting proteins:
Q96EK4-THA11_HUMAN
ENSP00000304689
for THAP11 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for THAP11
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 19008924 |
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA | 21873635 |
No data available for Pathways by source and SIGNOR curated interactions for THAP11 Gene
Transcripts for THAP11 Gene
mRNA/cDNA for THAP11 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000303596 1876 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for THAP11 - Starting at $85 >
- * THAP11 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for THAP11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for THAP11
-
Santa Cruz Biotechnology (SCBT) CRISPR for THAP11
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for THAP11
- Browse OriGene Inhibitory RNA Products For THAP11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for THAP11
Clone products for research
- Applied Biological Materials (abm): Clones for THAP11 - Starting at $45 >
- * THAP11 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for THAP11
- Addgene plasmids for THAP11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for THAP11
Relevant External Links for THAP11 Gene
- GeneLoc Exon Structure for
- THAP11
Expression for THAP11 Gene
This gene is overexpressed in Lung (49.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for THAP11 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for THAP11
SOURCE GeneReport for Unigene cluster for THAP11 Gene:
Hs.632200Evidence on tissue expression from TISSUES for THAP11 Gene
- Nervous system(4.6)
- Lung(2.4)
- Intestine(2)
Primer products for research
-
OriGene qPCR primer pairs for THAP11
-
OriGene qPCR primer pairs and template standards for THAP11
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for THAP11 Gene
Orthologs for THAP11 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | THAP11 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Thap11 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | THAP11 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | THAP11 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Thap11 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | THAP11 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | THAP11 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | THAP11 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | thap11 30 31 |
|
OneToOne | |
| wufa14e04 30 |
|
- Species where no ortholog for THAP11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for THAP11 Gene
- ENSEMBL:
- Gene Tree for THAP11 (if available)
- TreeFam:
- Gene Tree for THAP11 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for THAP11: view image
Paralogs for THAP11 Gene
No data available for Paralogs for THAP11 Gene
Variants for THAP11 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for THAP11 Gene
- THA11_HUMAN-Q96EK4
- The length of the poly-Gln region is variable in the population.
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for THAP11 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs188675529 | Likely Pathogenic: Mental retardation 3, X-linked | 67,842,794(+) |
C/G NM_020457.3(THAP11):c.240C>G (p.Phe80Leu) |
MISSENSE_VARIANT,INTRON | |
| rs377516180 | Benign: not provided | 67,842,920(+) |
ACAG/A NM_020457.3(THAP11):c.367_369CAG[9] (p.Gln132del) |
INFRAME_DELETION,INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
26.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.30;
6.58% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for THAP11 Gene
SNP Genotyping and Copy Number Assays for research
Disorders for THAP11 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| disorders of intracellular cobalamin metabolism |
|
|
| methylmalonic acidemia and homocysteinemia, cblx type |
|
|
Search THAP11 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for THAP11
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for THAP11 Gene
Publications for THAP11 Gene
- NMR studies of a new family of DNA binding proteins: the THAP proteins. (PMID: 23306615) Gervais V … Milon A (Journal of biomolecular NMR 2013) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. (PMID: 12575992) Roussigne M … Girard JP (Trends in biochemical sciences 2003) 2 3
- Selection system for genes encoding nuclear-targeted proteins. (PMID: 9853615) Ueki N … Muramatsu M (Nature biotechnology 1998) 3 4
- Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. (PMID: 8325628) Li SH … Ross CA (Genomics 1993) 2 3
ExternalLinks
Products for THAP11 Gene
- Custom Antibody ServicesOriGene Antibodies for THAP11
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for THAP11
- Origene Custom Protein Services for THAP11
- Origene shrna, sirna, and RNAi products in human, mouse, rat for THAP11
- Browse OriGene Inhibitory RNA Products For THAP11
- OriGene qPCR primer pairs for THAP11
- OriGene qPCR primer pairs and template standards for THAP11
- OriGene CRISPR knockouts for THAP11
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For THAP11
- Sino Biological Human cDNA Clone for THAP11
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for THAP11
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for THAP11
- Novus Biologicals proteins and lysates for THAP11
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for THAP11
- Abcam proteins for THAP11
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for THAP11 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for THAP11 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for THAP11 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for THAP11 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for THAP11
- Addgene plasmids for THAP11
- antibodies-online: Show 26 available THAP11 Antibodies ranked by validation data
- Compare Top THAP11 Antibodies
- antibodies-online: Search results for available THAP11 related products ranked by validation data
- antibodies-online: Search results for available THAP11 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for THAP11
- Search Santa Cruz Biotechnology (SCBT) for THAP11 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for THAP11
- Horizon Cell Lines for THAP11
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for THAP11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for THAP11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for THAP11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for THAP11
Sources for THAP11 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB