Aliases for TGM6 Gene
External Ids for TGM6 Gene
Previous HGNC Symbols for TGM6 Gene
Previous GeneCards Identifiers for TGM6 Gene
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for TGM6 Gene
TGM6 (Transglutaminase 6) is a Protein Coding gene. Diseases associated with TGM6 include Spinocerebellar Ataxia 35 and Leukemia, Acute Myeloid. Gene Ontology (GO) annotations related to this gene include protein-glutamine gamma-glutamyltransferase activity. An important paralog of this gene is ENSG00000286022.
UniProtKB/Swiss-Prot Summary for TGM6 Gene
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.