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Aliases for TGFB2-OT1 Gene
Subcategory (RNA class) for TGFB2-OT1 Gene
lncRNA
Number of RNA Genes sources:
2 / 17
Aliases for TGFB2-OT1 Gene
External Ids for TGFB2-OT1 Gene
- HGNC: 50629
- Entrez Gene: 103611157
- Ensembl: ENSG00000281453
Previous GeneCards Identifiers for TGFB2-OT1 Gene
- GC01U904379
Summaries for TGFB2-OT1 Gene
GeneCards Summary for TGFB2-OT1 Gene
TGFB2-OT1 (TGFB2 Overlapping Transcript 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TGFB2-OT1 include Loeys-Dietz Syndrome 4 and Loeys-Dietz Syndrome.
Additional gene information for TGFB2-OT1 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TGFB2-OT1 Gene
Genomics for TGFB2-OT1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TGFB2-OT1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01J218439 | Enhancer | 0.7 | Ensembl ENCODE dbSUPER | 0.7 | -2.9 | -2932 | 1.1 | TFAP4 CTCF | TGFB2 TGFB2-AS1 TGFB2-OT1 lnc-GPATCH2-8 LYPLAL1 | |
| GH01J218433 | Enhancer | 0.6 | Ensembl | 0.4 | -8.7 | -8724 | 0.6 | POLR2A ZNF316 MAFF MAFK MAFG ZNF366 FEZF1 PRDM6 BCL6B EMSY | LINC02869 TGFB2-OT1 lnc-GPATCH2-8 TGFB2 LYPLAL1 | |
| GH01J218430 | Enhancer | 0.6 | Ensembl ENCODE | 0.4 | -11.7 | -11724 | 1.8 | SCRT2 NR2F2 RXRA | LINC02869 TGFB2 lnc-GPATCH2-8 TGFB2-OT1 LYPLAL1 | |
| GH01J218452 | Enhancer | 0.3 | Ensembl | 0.4 | +9.9 | 9876 | 0.2 | SCRT2 NFE2 | LINC02869 TGFB2-OT1 TGFB2 LYPLAL1 | |
| GH01J218436 | Enhancer | 0.3 | Ensembl | 0.4 | -5.7 | -5724 | 0.6 | ZNF24 | LINC02869 TGFB2 TGFB2-AS1 TGFB2-OT1 lnc-GPATCH2-8 LYPLAL1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TGFB2-OT1 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for TGFB2-OT1 Gene
Genomic Locations for TGFB2-OT1 Gene
- chr1:218,442,625-218,443,996
- (GRCh38/hg38)
- Size:
- 1,372 bases
- Orientation:
- Plus strand
Genomic View for TGFB2-OT1 Gene
Genes around TGFB2-OT1 on UCSC Golden Path with GeneCards custom track
TGFB2-OT1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 1q41 by HGNC
- 1q41 by Entrez Gene
- 1q41 by Ensembl
TGFB2-OT1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TGFB2-OT1 Gene
Proteins for TGFB2-OT1 Gene
Post-translational modifications for TGFB2-OT1 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TGFB2-OT1
- Origene Custom Protein Services for TGFB2-OT1
No data available for DME Specific Peptides for TGFB2-OT1 Gene
Domains & Families for TGFB2-OT1 Gene
Gene Families for TGFB2-OT1 Gene
- HGNC:
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TGFB2-OT1 Gene
Function for TGFB2-OT1 Gene
Phenotypes From GWAS Catalog for TGFB2-OT1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Browse CRISPR knockouts for TGFB2-OT1
miRNA Products
Inhibitory RNA Products
Clone Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TGFB2-OT1 Gene
Localization for TGFB2-OT1 Gene
| Compartment | Confidence |
|---|---|
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TGFB2-OT1 Gene
Transcripts for TGFB2-OT1 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for TGFB2-OT1 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS00007E4360_9606 | lncRNA | 1370 | 3 |
HGNC: 50629, RefSeq: NR_125715, LNCipedia: TGFB2-OT1:1, |
| URS0000811731_9606 | lncRNA | 1371 | 2 |
Ensembl: ENST00000625474 (view in UCSC) , LNCipedia: TGFB2-OT1:2, |
| URS0000EA19EB_9606 | lncRNA | 1371 | 1 |
LncBook: HSALNT0289268, |
TGFB2-OT1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for TGFB2-OT1 Gene
- 1 NCBI additional mRNA sequence :
CRISPR Products
- Browse CRISPR knockouts for TGFB2-OT1
miRNA Products
Inhibitory RNA Products
Clone Products
Relevant External Links for TGFB2-OT1 Gene
- GeneLoc Exon Structure for
- TGFB2-OT1
Expression for TGFB2-OT1 Gene
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TGFB2-OT1 Gene
Orthologs for TGFB2-OT1 Gene
No data available for Orthologs for TGFB2-OT1 Gene
Paralogs for TGFB2-OT1 Gene
No data available for Paralogs for TGFB2-OT1 Gene
Variants for TGFB2-OT1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TGFB2-OT1 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 873770 | Uncertain Significance: Loeys-Dietz syndrome 4 | 218,443,233(+) | C/T | NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 873771 | Uncertain Significance: Loeys-Dietz syndrome 4 | 218,443,369(+) | C/T | NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 874726 | Uncertain Significance: Loeys-Dietz syndrome 4 | 218,443,714(+) | T/G | NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 874727 | Uncertain Significance: Loeys-Dietz syndrome 4 | 218,443,783(+) | G/T | NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 874728 | Uncertain Significance: Loeys-Dietz syndrome 4 | 218,443,858(+) | A/G | NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT |
Additional Variant Information for TGFB2-OT1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TGFB2-OT1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TGFB2-OT1 Gene
Disorders for TGFB2-OT1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| loeys-dietz syndrome 4 |
|
|
| loeys-dietz syndrome |
|
|
Search TGFB2-OT1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TGFB2-OT1
No data available for UniProtKB/Swiss-Prot and Genatlas for TGFB2-OT1 Gene
Publications for TGFB2-OT1 Gene
- A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459. (PMID: 25437332) Lu W … Miao J (Stem cells and development 2015) 2 3
- Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells. (PMID: 24879147) Ge D … Miao J (Autophagy 2014) 2 3
- A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells. (PMID: 26565952) Huang S … Miao J (Autophagy 2015) 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
Products for TGFB2-OT1 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TGFB2-OT1
- Origene Custom Protein Services for TGFB2-OT1
- Browse OriGene Inhibitory RNA Products For TGFB2-OT1
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for TGFB2-OT1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TGFB2-OT1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
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- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for TGFB2-OT1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for TGFB2-OT1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TGFB2-OT1
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for TGFB2-OT1
Sources for TGFB2-OT1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB