Aliases for TGFB2-OT1 Gene

Subcategory (RNA class) for TGFB2-OT1 Gene


Number of RNA Genes sources:

2 / 17

Aliases for TGFB2-OT1 Gene

  • TGFB2 Overlapping Transcript 1 2 3 5
  • TGFB2-OT1 2 5 165
  • HSALNG0010604 164
  • FLJ11812 2

External Ids for TGFB2-OT1 Gene

Previous GeneCards Identifiers for TGFB2-OT1 Gene

  • GC01U904379

Summaries for TGFB2-OT1 Gene

GeneCards Summary for TGFB2-OT1 Gene

TGFB2-OT1 (TGFB2 Overlapping Transcript 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TGFB2-OT1 include Loeys-Dietz Syndrome 4 and Loeys-Dietz Syndrome.

Additional gene information for TGFB2-OT1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TGFB2-OT1 Gene

Genomics for TGFB2-OT1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TGFB2-OT1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J218439 Enhancer 0.7 Ensembl ENCODE dbSUPER 0.7 -2.9 -2932 1.1 TFAP4 CTCF TGFB2 TGFB2-AS1 TGFB2-OT1 lnc-GPATCH2-8 LYPLAL1
GH01J218433 Enhancer 0.6 Ensembl 0.4 -8.7 -8724 0.6 POLR2A ZNF316 MAFF MAFK MAFG ZNF366 FEZF1 PRDM6 BCL6B EMSY LINC02869 TGFB2-OT1 lnc-GPATCH2-8 TGFB2 LYPLAL1
GH01J218430 Enhancer 0.6 Ensembl ENCODE 0.4 -11.7 -11724 1.8 SCRT2 NR2F2 RXRA LINC02869 TGFB2 lnc-GPATCH2-8 TGFB2-OT1 LYPLAL1
GH01J218452 Enhancer 0.3 Ensembl 0.4 +9.9 9876 0.2 SCRT2 NFE2 LINC02869 TGFB2-OT1 TGFB2 LYPLAL1
GH01J218436 Enhancer 0.3 Ensembl 0.4 -5.7 -5724 0.6 ZNF24 LINC02869 TGFB2 TGFB2-AS1 TGFB2-OT1 lnc-GPATCH2-8 LYPLAL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TGFB2-OT1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TGFB2-OT1 Gene

Genomic Locations for TGFB2-OT1 Gene
1,372 bases
Plus strand

Genomic View for TGFB2-OT1 Gene

Genes around TGFB2-OT1 on UCSC Golden Path with GeneCards custom track
TGFB2-OT1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
TGFB2-OT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TGFB2-OT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TGFB2-OT1 Gene

Proteins for TGFB2-OT1 Gene

Post-translational modifications for TGFB2-OT1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TGFB2-OT1 Gene

Domains & Families for TGFB2-OT1 Gene

Gene Families for TGFB2-OT1 Gene

genes like me logo Genes that share domains with TGFB2-OT1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TGFB2-OT1 Gene

Function for TGFB2-OT1 Gene

Phenotypes From GWAS Catalog for TGFB2-OT1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TGFB2-OT1 Gene

Localization for TGFB2-OT1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TGFB2-OT1 gene
Compartment Confidence
extracellular 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TGFB2-OT1 Gene

Pathways & Interactions for TGFB2-OT1 Gene

PathCards logo

SuperPathways for TGFB2-OT1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TGFB2-OT1 Gene


No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TGFB2-OT1 Gene

Drugs & Compounds for TGFB2-OT1 Gene

No Compound Related Data Available

Transcripts for TGFB2-OT1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TGFB2-OT1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00007E4360_9606 lncRNA 1370 3

HGNC: 50629,

RefSeq: NR_125715,

LNCipedia: TGFB2-OT1:1,

URS0000811731_9606 lncRNA 1371 2

Ensembl: ENST00000625474 (view in UCSC) ,

LNCipedia: TGFB2-OT1:2,

URS0000EA19EB_9606 lncRNA 1371 1

LncBook: HSALNT0289268,

TGFB2-OT1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TGFB2-OT1 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for TGFB2-OT1 Gene

No ASD Table

Relevant External Links for TGFB2-OT1 Gene

GeneLoc Exon Structure for

Expression for TGFB2-OT1 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TGFB2-OT1 Gene

Orthologs for TGFB2-OT1 Gene

Evolution for TGFB2-OT1 Gene

Gene Tree for TGFB2-OT1 (if available)
Gene Tree for TGFB2-OT1 (if available)

No data available for Orthologs for TGFB2-OT1 Gene

Paralogs for TGFB2-OT1 Gene

No data available for Paralogs for TGFB2-OT1 Gene

Variants for TGFB2-OT1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TGFB2-OT1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
873770 Uncertain Significance: Loeys-Dietz syndrome 4 218,443,233(+) C/T NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT
873771 Uncertain Significance: Loeys-Dietz syndrome 4 218,443,369(+) C/T NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT
874726 Uncertain Significance: Loeys-Dietz syndrome 4 218,443,714(+) T/G NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT
874727 Uncertain Significance: Loeys-Dietz syndrome 4 218,443,783(+) G/T NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT
874728 Uncertain Significance: Loeys-Dietz syndrome 4 218,443,858(+) A/G NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR_VARIANT

Additional dbSNP identifiers (rs#s) for TGFB2-OT1 Gene

Structural Variations from Database of Genomic Variants (DGV) for TGFB2-OT1 Gene

Variant ID Type Subtype PubMed ID
nsv832603 CNV gain 17160897

Additional Variant Information for TGFB2-OT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TGFB2-OT1 Gene

Disorders for TGFB2-OT1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for TGFB2-OT1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
loeys-dietz syndrome 4
  • lds4
loeys-dietz syndrome
  • furlong syndrome
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for TGFB2-OT1

genes like me logo Genes that share disorders with TGFB2-OT1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TGFB2-OT1 Gene

Publications for TGFB2-OT1 Gene

  1. A 3'UTR-associated RNA, FLJ11812 maintains stemness of human embryonic stem cells by targeting miR-4459. (PMID: 25437332) Lu W … Miao J (Stem cells and development 2015) 2 3
  2. Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells. (PMID: 24879147) Ge D … Miao J (Autophagy 2014) 2 3
  3. A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells. (PMID: 26565952) Huang S … Miao J (Autophagy 2015) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3

Products for TGFB2-OT1 Gene

Sources for TGFB2-OT1 Gene