Aliases for TFG Gene
External Ids for TFG Gene
Previous GeneCards Identifiers for TFG Gene
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
GeneCards Summary for TFG Gene
TFG (Trafficking From ER To Golgi Regulator) is a Protein Coding gene. Diseases associated with TFG include Spastic Paraplegia 57, Autosomal Recessive and Neuropathy, Hereditary Motor And Sensory, Okinawa Type. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include identical protein binding and obsolete signal transducer activity.
UniProtKB/Swiss-Prot Summary for TFG Gene
Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858).