Aliases for TFAP4 Gene
External Ids for TFAP4 Gene
Previous GeneCards Identifiers for TFAP4 Gene
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]
GeneCards Summary for TFAP4 Gene
TFAP4 (Transcription Factor AP-4) is a Protein Coding gene. Among its related pathways are Proteoglycans in cancer. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is MLXIP.
UniProtKB/Swiss-Prot Summary for TFAP4 Gene
Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'-CAGCTG-3'.