Aliases for TEX49 Gene

Aliases for TEX49 Gene

  • Testis Expressed 49 2 3 5
  • Long Intergenic Non-Protein Coding RNA 935 2 3
  • Testis-Expressed Protein 49 3 4
  • LINC00935 3

External Ids for TEX49 Gene

Previous HGNC Symbols for TEX49 Gene

  • LINC00935

Previous GeneCards Identifiers for TEX49 Gene

  • GC12P048728

Summaries for TEX49 Gene

GeneCards Summary for TEX49 Gene

TEX49 (Testis Expressed 49) is a Protein Coding gene. Diseases associated with TEX49 include Lethal Congenital Contracture Syndrome 8.

Additional gene information for TEX49 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TEX49 Gene

Genomics for TEX49 Gene

GeneHancer (GH) Regulatory Elements for TEX49 Gene

Promoters and enhancers for TEX49 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J048727 Promoter 0.4 EPDnew 750.6 +0.0 3 0.1 RFX1 TEX49 piR-56759-118 piR-54764-116 RF00017-1134 MG828730-015
GH12J048753 Enhancer 0.8 Ensembl ENCODE 0.3 +26.3 26277 0.9 CTCF ZNF362 CC2D1A RAD21 ZNF384 CEBPG SP7 IKZF1 CEBPA REST ADCY6 CACNB3 RNU6-600P KANSL2 DDN-AS1 RF00017-1134 ENSG00000257653 TEX49 MG828730-015
GH12J048765 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.3 +38.5 38465 3 MYC IKZF1 EED CTBP1 KLF4 ELF1 RUNX3 GABPA NR2F1 VEZF1 ENSG00000257653 ADCY6 CACNB3 KANSL2 ASB8 RF00017-1134 TEX49 MG828730-015
GH12J048750 Enhancer 0.5 Ensembl ENCODE 0.3 +23.5 23459 1.4 IKZF1 ZNF664 RF00017-1134 KANSL2 ADCY6 CACNB3 ENSG00000257653 TEX49 MG828730-015
GH12J048749 Enhancer 0.2 Ensembl 0.3 +22.1 22066 0.2 RF00017-1134 ADCY6 CACNB3 ENSG00000257653 TEX49 MG828730-015
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TEX49 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TEX49 Gene

Genomic Locations for TEX49 Gene
chr12:48,727,435-48,765,786
(GRCh38/hg38)
Size:
38,352 bases
Orientation:
Plus strand
chr12:49,121,218-49,159,569
(GRCh37/hg19)
Size:
38,352 bases
Orientation:
Plus strand

Genomic View for TEX49 Gene

Genes around TEX49 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX49 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX49 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX49 Gene

Proteins for TEX49 Gene

  • Protein details for TEX49 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1B0GTD5-TEX49_HUMAN
    Recommended name:
    Testis-expressed protein 49
    Protein Accession:
    A0A1B0GTD5

    Protein attributes for TEX49 Gene

    Size:
    131 amino acids
    Molecular mass:
    15631 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX49 Gene

Post-translational modifications for TEX49 Gene

Other Protein References for TEX49 Gene

No data available for DME Specific Peptides for TEX49 Gene

Domains & Families for TEX49 Gene

Gene Families for TEX49 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX49 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TEX49: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TEX49 Gene

Function for TEX49 Gene

Phenotypes From GWAS Catalog for TEX49 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX49 Gene

Localization for TEX49 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TEX49 Gene

Pathways & Interactions for TEX49 Gene

PathCards logo

SuperPathways for TEX49 Gene

No Data Available

Interacting Proteins for TEX49 Gene

Gene Ontology (GO) - Biological Process for TEX49 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX49 Gene

Drugs & Compounds for TEX49 Gene

No Compound Related Data Available

Transcripts for TEX49 Gene

mRNA/cDNA for TEX49 Gene

(2) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TEX49 Gene

No ASD Table

Relevant External Links for TEX49 Gene

GeneLoc Exon Structure for
TEX49
ECgene alternative splicing isoforms for
TEX49

Expression for TEX49 Gene

NURSA nuclear receptor signaling pathways regulating expression of TEX49 Gene:

TEX49
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX49 Gene

Orthologs for TEX49 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX49 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LINC00935 33
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LINC00935 33
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4930415O20Rik 33
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia LINC00935 33
  • 37 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia LINC00935 33
  • 33 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LINC00935 33
  • 30 (a)
OneToOne
Species where no ortholog for TEX49 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TEX49 Gene

ENSEMBL:
Gene Tree for TEX49 (if available)
TreeFam:
Gene Tree for TEX49 (if available)

Paralogs for TEX49 Gene

No data available for Paralogs for TEX49 Gene

Variants for TEX49 Gene

Sequence variations from dbSNP and Humsavar for TEX49 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs786204798 pathogenic, Lethal congenital contracture syndrome 8 48,768,972(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000080486 -- 48,733,616(+) A/G intron_variant
rs1000156367 -- 48,745,237(+) C/G intron_variant
rs1000175226 -- 48,746,673(+) C/A/T intron_variant
rs1000354407 -- 48,753,157(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TEX49 Gene

Variant ID Type Subtype PubMed ID
esv3549178 CNV deletion 23714750
esv3580269 CNV loss 25503493

Variation tolerance for TEX49 Gene

Gene Damage Index Score: 2.00; 36.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX49 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX49

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX49 Gene

Disorders for TEX49 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TEX49 Gene - From: GeneCards

Disorder Aliases PubMed IDs
lethal congenital contracture syndrome 8
  • lccs8
- elite association - COSMIC cancer census association via MalaCards
Search TEX49 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TEX49

genes like me logo Genes that share disorders with TEX49: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TEX49 Gene

Publications for TEX49 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 4 56
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 56

Products for TEX49 Gene

Sources for TEX49 Gene