Aliases for TEX47 Gene

Aliases for TEX47 Gene

  • Testis Expressed 47 2 3 5
  • Testis-Expressed Protein 47 3 4
  • C7orf62 3 4
  • Chromosome 7 Open Reading Frame 62 2
  • Uncharacterized Protein C7orf62 3
  • MGC26647 2
  • TEX47 5

External Ids for TEX47 Gene

Previous HGNC Symbols for TEX47 Gene

  • C7orf62

Summaries for TEX47 Gene

GeneCards Summary for TEX47 Gene

TEX47 (Testis Expressed 47) is a Protein Coding gene.

Additional gene information for TEX47 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TEX47 Gene

Genomics for TEX47 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TEX47 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J088795 Promoter 0.5 EPDnew 600.7 +2.2 2200 0.1 POLR2A SMARCA4 TEX47 lnc-ADAM22-6 ZNF804B
GH07J088289 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 9.8 +507.0 506965 4.3 CREB1 ZBTB33 TARDBP FOXA1 ATF7 BRCA1 BMI1 CTBP1 CEBPB ZNF444 EIF4A1P13 ENSG00000207094 ZNF804B TEX47 SRI STEAP4 lnc-STEAP4-1 ENSG00000228113
GH07J088309 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 9.2 +481.0 481034 15 TCF12 IKZF2 SP1 PKNOX1 MNT RELB CEBPB USF1 ARNT ELF1 STEAP4 TEX47 ENSG00000228113 SRI TP53TG1 LOC107986815 ZNF804B
GH07J088278 Enhancer 0.9 Ensembl ENCODE dbSUPER 9.7 +519.8 519836 4.6 CEBPG CEBPB ZNF316 MAFF MAFK MAFG EP300 SPI1 STAT3 GABPA TEX47 SRI lnc-STEAP4-1 STEAP4 ENSG00000228113
GH07J088347 Enhancer 0.7 Ensembl ENCODE 10.2 +451.3 451337 2.8 CTCF RAD21 PKNOX1 RELB ZNF654 HNF4A TBX21 ZNF143 IKZF1 EIF4A1P13 ENSG00000207094 TEX47 SRI LOC107986815 piR-61240-267 STEAP4 ENSG00000228113 ZNF804B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TEX47 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TEX47

Genomic Locations for TEX47 Gene

Genomic Locations for TEX47 Gene
chr7:88,794,106-88,797,937
(GRCh38/hg38)
Size:
3,832 bases
Orientation:
Minus strand
chr7:88,423,420-88,425,035
(GRCh37/hg19)
Size:
1,616 bases
Orientation:
Minus strand

Genomic View for TEX47 Gene

Genes around TEX47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX47 Gene

Proteins for TEX47 Gene

  • Protein details for TEX47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBZ9-TEX47_HUMAN
    Recommended name:
    Testis-expressed protein 47
    Protein Accession:
    Q8TBZ9

    Protein attributes for TEX47 Gene

    Size:
    253 amino acids
    Molecular mass:
    29483 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX47 Gene

Post-translational modifications for TEX47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX47 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX47 Gene

Domains & Families for TEX47 Gene

Gene Families for TEX47 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX47 Gene

ProtoNet:
genes like me logo Genes that share domains with TEX47: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TEX47 Gene

Function for TEX47 Gene

Phenotypes From GWAS Catalog for TEX47 Gene

genes like me logo Genes that share phenotypes with TEX47: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX47 Gene

Localization for TEX47 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX47 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 2
golgi apparatus 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (1)
  • Nucleoplasm (1)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TEX47 Gene

Pathways & Interactions for TEX47 Gene

PathCards logo

SuperPathways for TEX47 Gene

No Data Available

Interacting Proteins for TEX47 Gene

Selected Interacting proteins: Q8TBZ9-TEX47_HUMAN for TEX47 Gene via UniProtKB

Symbol External ID(s) Details
MEOX2

Gene Ontology (GO) - Biological Process for TEX47 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX47 Gene

Drugs & Compounds for TEX47 Gene

No Compound Related Data Available

Transcripts for TEX47 Gene

mRNA/cDNA for TEX47 Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TEX47 Gene

No ASD Table

Relevant External Links for TEX47 Gene

GeneLoc Exon Structure for
TEX47

Expression for TEX47 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TEX47

mRNA Expression by UniProt/SwissProt for TEX47 Gene:

Q8TBZ9-TEX47_HUMAN
Tissue specificity: Testis-specific.

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX47 Gene

Orthologs for TEX47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX47 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C7H7orf62 30
  • 99.21 (n)
C7orf62 31
  • 98 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia C14H7orf62 30
  • 82.08 (n)
C7orf62 31
  • 75 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia C4H7orf62 30 31
  • 81.61 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia 4921511H03Rik 30 31
  • 75.63 (n)
OneToOne
Tex47 17
Rat
(Rattus norvegicus)
Mammalia RGD1564345 30
  • 74.97 (n)
Oppossum
(Monodelphis domestica)
Mammalia C7orf62 31
  • 61 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia C7orf62 31
  • 51 (a)
OneToOne
Chicken
(Gallus gallus)
Aves C7orf62 31
  • 33 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 39 (a)
OneToMany
-- 31
  • 34 (a)
OneToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC100497111 30
  • 46.7 (n)
Zebrafish
(Danio rerio)
Actinopterygii LOC100006770 30
  • 44.91 (n)
C7orf62 31
  • 27 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 28 (a)
OneToOne
Species where no ortholog for TEX47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for TEX47 Gene

ENSEMBL:
Gene Tree for TEX47 (if available)
TreeFam:
Gene Tree for TEX47 (if available)

Paralogs for TEX47 Gene

No data available for Paralogs for TEX47 Gene

Variants for TEX47 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TEX47 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs2293583 - p.Ile126Val
rs2373396 - p.Asp48His
rs2373397 - p.Glu221Lys
rs2373398 - p.Glu221Ala
rs34276371 - p.Cys186Ser

Additional dbSNP identifiers (rs#s) for TEX47 Gene

Structural Variations from Database of Genomic Variants (DGV) for TEX47 Gene

Variant ID Type Subtype PubMed ID
dgv11493n54 CNV gain 21841781
dgv6525n100 CNV gain 25217958
dgv6526n100 CNV gain 25217958
esv2752187 CNV gain 17911159
esv2752188 CNV gain 17911159
esv2764019 CNV loss 21179565
esv3576400 CNV gain 25503493
esv3576401 CNV gain 25503493
nsv1015471 CNV gain 25217958
nsv464626 CNV gain 19166990
nsv515995 CNV gain+loss 19592680

Variation tolerance for TEX47 Gene

Residual Variation Intolerance Score: 69.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.82; 73.82% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX47 Gene

Disorders for TEX47 Gene

No disorders were found for TEX47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX47 Gene

Publications for TEX47 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 2 3 4
  2. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  3. Novel associations for hypothyroidism include known autoimmune risk loci. (PMID: 22493691) Eriksson N … Do CB (PloS one 2012) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P … Vidal M (Genomics 2007) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for TEX47 Gene

Sources for TEX47 Gene