Aliases for TEX33 Gene

Aliases for TEX33 Gene

  • Testis Expressed 33 2 3 5
  • EAN57 2 3 4
  • Testis-Expressed Protein 33 3 4
  • C22orf33 3 4
  • Testis-Expressed Sequence 33 Protein 3
  • Chromosome 22 Open Reading Frame 33 2
  • Protein EAN57 3
  • CE81G9.2 3
  • MGC35206 2
  • TEX33 5

External Ids for TEX33 Gene

Previous HGNC Symbols for TEX33 Gene

  • C22orf33

Previous GeneCards Identifiers for TEX33 Gene

  • GC22M037388

Summaries for TEX33 Gene

GeneCards Summary for TEX33 Gene

TEX33 (Testis Expressed 33) is a Protein Coding gene.

Additional gene information for TEX33 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TEX33 Gene

Genomics for TEX33 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TEX33 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TEX33 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TEX33

Genomic Locations for TEX33 Gene

Genomic Locations for TEX33 Gene
chr22:36,991,120-37,007,864
(GRCh38/hg38)
Size:
16,745 bases
Orientation:
Minus strand
chr22:37,387,160-37,403,882
(GRCh37/hg19)
Size:
16,723 bases
Orientation:
Minus strand

Genomic View for TEX33 Gene

Genes around TEX33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX33 Gene

Proteins for TEX33 Gene

  • Protein details for TEX33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O43247-TEX33_HUMAN
    Recommended name:
    Testis-expressed protein 33
    Protein Accession:
    O43247
    Secondary Accessions:
    • B1AH46
    • Q6ICF2
    • Q8IVQ2
    • Q9Y4V8

    Protein attributes for TEX33 Gene

    Size:
    280 amino acids
    Molecular mass:
    30725 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA72029.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for TEX33 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX33 Gene

Post-translational modifications for TEX33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX33 Gene

No data available for DME Specific Peptides for TEX33 Gene

Domains & Families for TEX33 Gene

Gene Families for TEX33 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX33 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX33 Gene

GenScript: Design optimal peptide antigens:
  • Chromosome 22 open reading frame 33 (B1AH47_HUMAN)
  • Protein EAN57 (EAN57_HUMAN)
genes like me logo Genes that share domains with TEX33: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TEX33 Gene

Function for TEX33 Gene

Phenotypes From GWAS Catalog for TEX33 Gene

genes like me logo Genes that share phenotypes with TEX33: view

Animal Model Products

CRISPR Products

miRNA for TEX33 Gene

miRTarBase miRNAs that target TEX33

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEX33

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX33 Gene

Localization for TEX33 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX33 gene
Compartment Confidence
nucleus 2
mitochondrion 1
peroxisome 0
cytosol 0

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TEX33 Gene

Pathways & Interactions for TEX33 Gene

PathCards logo

SuperPathways for TEX33 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX33 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX33 Gene

Drugs & Compounds for TEX33 Gene

No Compound Related Data Available

Transcripts for TEX33 Gene

mRNA/cDNA for TEX33 Gene

2 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEX33

Alternative Splicing Database (ASD) splice patterns (SP) for TEX33 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
SP1:
SP2: -

Relevant External Links for TEX33 Gene

GeneLoc Exon Structure for
TEX33

Expression for TEX33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TEX33 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX33 Gene

This gene is overexpressed in Testis (x52.4).

Protein differential expression in normal tissues from HIPED for TEX33 Gene

This gene is overexpressed in Testis (65.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEX33 Gene



Protein tissue co-expression partners for TEX33 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TEX33

SOURCE GeneReport for Unigene cluster for TEX33 Gene:

Hs.124502
genes like me logo Genes that share expression patterns with TEX33: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX33 Gene

Orthologs for TEX33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX33 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia TEX33 30 31
  • 99.4 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia TEX33 30
  • 81.21 (n)
MGC133880 31
  • 72 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia TEX33 30 31
  • 80.15 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Tex33 30 17 31
  • 77.11 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Tex33 30
  • 75.76 (n)
Oppossum
(Monodelphis domestica)
Mammalia TEX33 31
  • 44 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia TEX33 31
  • 44 (a)
OneToOne
Chicken
(Gallus gallus)
Aves TEX33 31
  • 46 (a)
OneToOne
Species where no ortholog for TEX33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TEX33 Gene

ENSEMBL:
Gene Tree for TEX33 (if available)
TreeFam:
Gene Tree for TEX33 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TEX33: view image

Paralogs for TEX33 Gene

No data available for Paralogs for TEX33 Gene

Variants for TEX33 Gene

Additional dbSNP identifiers (rs#s) for TEX33 Gene

Structural Variations from Database of Genomic Variants (DGV) for TEX33 Gene

Variant ID Type Subtype PubMed ID
esv34015 CNV loss 18971310
nsv1057409 CNV gain 25217958
nsv459882 CNV gain 19166990
nsv588984 CNV gain 21841781
nsv829203 CNV loss 20364138
nsv834187 CNV loss 17160897
nsv955154 CNV deletion 24416366

Variation tolerance for TEX33 Gene

Residual Variation Intolerance Score: 89% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.66; 78.43% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX33

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TEX33 Gene

Disorders for TEX33 Gene

No disorders were found for TEX33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX33 Gene

Publications for TEX33 Gene

  1. Identification of testis 14-3-3 binding proteins by tandem affinity purification. (PMID: 22332119) Puri P … Vijayaraghavan S (Spermatogenesis 2011) 2 3
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins. (PMID: 29513927) Tomkins JE … Manzoni C (Proteomics 2018) 3
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3

Products for TEX33 Gene

Sources for TEX33 Gene