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Aliases for TEX264 Gene

Aliases for TEX264 Gene

  • Testis Expressed 264 2 3 5
  • Testis Expressed Gene 264 2 3
  • ZSIG11 3 4
  • Testis-Expressed Sequence 264 Protein 3
  • Putative Secreted Protein Zsig11 4
  • Testis Expressed Sequence 264 2
  • Testis-Expressed Protein 264 3

External Ids for TEX264 Gene

Previous GeneCards Identifiers for TEX264 Gene

  • GC03P051680

Summaries for TEX264 Gene

GeneCards Summary for TEX264 Gene

TEX264 (Testis Expressed 264) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+.

Additional gene information for TEX264 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX264 Gene

Genomics for TEX264 Gene

GeneHancer (GH) Regulatory Elements for TEX264 Gene

Promoters and enhancers for TEX264 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I051668 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 570.4 +8.2 8167 4.1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 POLR2B ZNF766 ZNF207 ZNF143 TEX264 DCAF1 RRP9 RNU6ATAC29P RBM15B RAD54L2 DOCK3 GRM2 PIR41340 RNA5SP132
GH03I051383 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 9.7 -274.5 -274492 9.5 HDGF PKNOX1 CLOCK SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 IRF4 MANF PIR60056 RBM15B DCAF1 RRP9 RAD54L2 TEX264 GRM2 CACNA2D2 GPR62
GH03I051339 Enhancer 1.2 FANTOM5 Ensembl ENCODE 17.7 -322.2 -322171 2.9 JUN MAX RFX5 TEAD3 FOSL1 ZFHX2 POLR2A SMARCC2 RCOR1 FOSL2 TEX264 PIR61668 MANF DOCK3
GH03I051684 Enhancer 1.2 FANTOM5 Ensembl ENCODE 17.4 +23.5 23538 3.6 ETV1 TAL1 MAX EBF1 TCF12 NCOR1 POLR2A EGR1 VEZF1 SCRT2 TEX264 DCAF1 RNU6ATAC29P IQCF6 RPL29 RNA5SP132 PIR41340
GH03I051621 Enhancer 1 Ensembl ENCODE 13.8 -40.8 -40784 1.4 ELF3 THRB RAD21 RARA YY1 RXRA CEBPB REST NR2F2 NFIL3 TEX264 GRM2 GC03P051614 GC03P051629 RAD54L2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TEX264 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TEX264 gene promoter:

Genomic Locations for TEX264 Gene

Genomic Locations for TEX264 Gene
chr3:51,662,693-51,704,323
(GRCh38/hg38)
Size:
41,631 bases
Orientation:
Plus strand
chr3:51,696,709-51,738,339
(GRCh37/hg19)

Genomic View for TEX264 Gene

Genes around TEX264 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX264 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX264 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX264 Gene

Proteins for TEX264 Gene

  • Protein details for TEX264 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6I9-TX264_HUMAN
    Recommended name:
    Testis-expressed protein 264
    Protein Accession:
    Q9Y6I9
    Secondary Accessions:
    • B3KN87
    • Q9UKD7

    Protein attributes for TEX264 Gene

    Size:
    313 amino acids
    Molecular mass:
    34189 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD52584.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TEX264 Gene

Post-translational modifications for TEX264 Gene

  • Ubiquitination at posLast=7373
  • Glycosylation at isoforms=45
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Abcam antibodies for TEX264

No data available for DME Specific Peptides for TEX264 Gene

Domains & Families for TEX264 Gene

Gene Families for TEX264 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for TEX264 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX264 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX264: view

No data available for UniProtKB/Swiss-Prot for TEX264 Gene

Function for TEX264 Gene

Phenotypes From GWAS Catalog for TEX264 Gene

Gene Ontology (GO) - Molecular Function for TEX264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TEX264: view

Phenotypes for TEX264 Gene

genes like me logo Genes that share phenotypes with TEX264: view

Animal Model Products

  • Taconic Biosciences Mouse Models for TEX264

miRNA for TEX264 Gene

miRTarBase miRNAs that target TEX264

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX264 Gene

Localization for TEX264 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX264 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX264 gene
Compartment Confidence
extracellular 5
plasma membrane 2
nucleus 2
cytosol 2
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoli (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TEX264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0031093 platelet alpha granule lumen TAS --
GO:0070062 extracellular exosome HDA,IDA 23376485
genes like me logo Genes that share ontologies with TEX264: view

Pathways & Interactions for TEX264 Gene

genes like me logo Genes that share pathways with TEX264: view

Gene Ontology (GO) - Biological Process for TEX264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002576 platelet degranulation TAS --
genes like me logo Genes that share ontologies with TEX264: view

No data available for SIGNOR curated interactions for TEX264 Gene

Drugs & Compounds for TEX264 Gene

No Compound Related Data Available

Transcripts for TEX264 Gene

Unigene Clusters for TEX264 Gene

Testis expressed 264:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX264 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d · 10e ^ 11a · 11b ^ 12a · 12b ·
SP1: - - - - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - - - - - - -
SP6: - - - - - - - - - -
SP7: - - - - -
SP8:
SP9: - - - - - - - - - -
SP10: - - - -
SP11: - -
SP12: - - - - - -
SP13: -
SP14: - - - - - -
SP15: - - - - -

ExUns: 12c · 12d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:

Relevant External Links for TEX264 Gene

GeneLoc Exon Structure for
TEX264
ECgene alternative splicing isoforms for
TEX264

Expression for TEX264 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX264 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TEX264 Gene

This gene is overexpressed in Bone (12.0), Lung (11.7), Breast (10.5), and Pancreas (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX264 Gene



Protein tissue co-expression partners for TEX264 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TEX264 Gene:

TEX264

SOURCE GeneReport for Unigene cluster for TEX264 Gene:

Hs.517864

Evidence on tissue expression from TISSUES for TEX264 Gene

  • Nervous system(4.6)
  • Skin(4.3)
  • Liver(4.2)
  • Kidney(2)
genes like me logo Genes that share expression patterns with TEX264: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX264 Gene

Orthologs for TEX264 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX264 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX264 33
  • 90.24 (n)
cow
(Bos Taurus)
Mammalia TEX264 33 34
  • 88.66 (n)
dog
(Canis familiaris)
Mammalia TEX264 33 34
  • 88.09 (n)
mouse
(Mus musculus)
Mammalia Tex264 33 16 34
  • 85.48 (n)
rat
(Rattus norvegicus)
Mammalia Tex264 33
  • 85.25 (n)
oppossum
(Monodelphis domestica)
Mammalia TEX264 34
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TEX264 34
  • 66 (a)
OneToOne
chicken
(Gallus gallus)
Aves TEX264 33 34
  • 70.9 (n)
lizard
(Anolis carolinensis)
Reptilia TEX264 34
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tex264 33
  • 58.27 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100000155 33
  • 56.63 (n)
TEX264 34
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 35 (a)
OneToMany
CSA.5905 34
  • 35 (a)
OneToMany
Species where no ortholog for TEX264 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TEX264 Gene

ENSEMBL:
Gene Tree for TEX264 (if available)
TreeFam:
Gene Tree for TEX264 (if available)

Paralogs for TEX264 Gene

(1) SIMAP similar genes for TEX264 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for TEX264 Gene

genes like me logo Genes that share paralogs with TEX264: view

No data available for Paralogs for TEX264 Gene

Variants for TEX264 Gene

Sequence variations from dbSNP and Humsavar for TEX264 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000052044 -- 51,702,548(+) C/G genic_downstream_transcript_variant, intron_variant
rs1000111054 -- 51,688,323(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000215953 -- 51,698,167(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000217574 -- 51,686,974(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000223926 -- 51,692,531(+) C/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TEX264 Gene

Variant ID Type Subtype PubMed ID
dgv8322n54 CNV loss 21841781
nsv508921 CNV insertion 20534489
nsv954856 CNV deletion 24416366

Variation tolerance for TEX264 Gene

Residual Variation Intolerance Score: 20.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.24; 76.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX264 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX264

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX264 Gene

Disorders for TEX264 Gene

Additional Disease Information for TEX264

No disorders were found for TEX264 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX264 Gene

Publications for TEX264 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 2 3 4 58
  2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for TEX264 Gene

Sources for TEX264 Gene

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