Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TEX22 Gene

Aliases for TEX22 Gene

  • Testis Expressed 22 2 3 5
  • Testis-Expressed Protein 22 3 4
  • Testis-Expressed Sequence 22 Protein 3
  • Testis Expressed Gene 22 3

External Ids for TEX22 Gene

Previous GeneCards Identifiers for TEX22 Gene

  • GC14P105865

Summaries for TEX22 Gene

GeneCards Summary for TEX22 Gene

TEX22 (Testis Expressed 22) is a Protein Coding gene.

Additional gene information for TEX22 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX22 Gene

Genomics for TEX22 Gene

GeneHancer (GH) Regulatory Elements for TEX22 Gene

Promoters and enhancers for TEX22 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J105396 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 600.7 -0.2 -152 3.2 SP1 ELF3 ZFX ZNF148 NKRF POLR2A ZNF121 ZNF687 AHR ZBTB7A TEX22 MTA1 SIVA1 GC14P105395 GC14M105345 PACS2
GH14J105312 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 11.5 -83.1 -83101 5.4 ZFX ZNF148 MAFK ZNF639 CREB1 GLIS2 POLR2A HMG20B ZBTB8A NRF1 BRF1 PACS2 MTA1 ENSG00000225200 ENSG00000257270 TEX22 NUDT14 JAG2 GC14M105304
GH14J105447 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.8 +50.0 50022 3 CTCF GLIS2 ZBTB33 ZBTB8A ZIC2 ZNF143 REST PATZ1 ZNF692 TRIM22 TEX22 ENSG00000257270 GC14M105345 MTA1
GH14J105451 Enhancer 0.8 Ensembl ENCODE dbSUPER 11.8 +52.9 52879 0.4 ZBTB8A ZNF600 TEX22 GC14M105345 MTA1
GH14J105303 Enhancer 0.6 Ensembl dbSUPER 11.3 -93.5 -93537 2.4 KLF9 KLF1 TEX22 NUDT14 JAG2 BRF1 BTBD6 PACS2 GC14M105304
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TEX22 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TEX22 Gene

Genomic Locations for TEX22 Gene
chr14:105,398,538-105,450,106
(GRCh38/hg38)
Size:
51,569 bases
Orientation:
Plus strand
chr14:105,864,916-105,916,443
(GRCh37/hg19)
Size:
51,528 bases
Orientation:
Plus strand

Genomic View for TEX22 Gene

Genes around TEX22 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX22 Gene

Proteins for TEX22 Gene

  • Protein details for TEX22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J3V5-TEX22_HUMAN
    Recommended name:
    Testis-expressed protein 22
    Protein Accession:
    C9J3V5

    Protein attributes for TEX22 Gene

    Size:
    150 amino acids
    Molecular mass:
    16880 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX22 Gene

Post-translational modifications for TEX22 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX22 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX22 Gene

Domains & Families for TEX22 Gene

Gene Families for TEX22 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX22 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TEX22 Gene

GenScript: Design optimal peptide antigens:
  • Testis-expressed sequence 22 protein (TEX22_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX22: view

No data available for UniProtKB/Swiss-Prot for TEX22 Gene

Function for TEX22 Gene

Phenotypes From GWAS Catalog for TEX22 Gene

Phenotypes for TEX22 Gene

MGI mutant phenotypes for TEX22:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TEX22: view

Animal Models for TEX22 Gene

MGI Knock Outs for TEX22:

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for TEX22 - Now 50% OFF >
  • * TEX22 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * TEX22 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TEX22 Gene

Localization for TEX22 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX22 Gene

Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX22 gene
Compartment Confidence
nucleus 3
cytosol 0

Gene Ontology (GO) - Cellular Components for TEX22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001669 acrosomal vesicle IEA --
GO:0005737 cytoplasm IEA --
GO:0031410 cytoplasmic vesicle IEA --
genes like me logo Genes that share ontologies with TEX22: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TEX22 Gene

Pathways & Interactions for TEX22 Gene

PathCards logo

SuperPathways for TEX22 Gene

No Data Available

Interacting Proteins for TEX22 Gene

Gene Ontology (GO) - Biological Process for TEX22 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX22 Gene

Drugs & Compounds for TEX22 Gene

No Compound Related Data Available

Transcripts for TEX22 Gene

mRNA/cDNA for TEX22 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for TEX22 Gene

Testis expressed 22:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for TEX22 - Now 50% OFF >
  • * TEX22 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * TEX22 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for TEX22 Gene

No ASD Table

Relevant External Links for TEX22 Gene

GeneLoc Exon Structure for
TEX22
ECgene alternative splicing isoforms for
TEX22

Expression for TEX22 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX22 Gene

mRNA differential expression in normal tissues according to GTEx for TEX22 Gene

This gene is overexpressed in Testis (x15.1).

NURSA nuclear receptor signaling pathways regulating expression of TEX22 Gene:

TEX22

SOURCE GeneReport for Unigene cluster for TEX22 Gene:

Hs.729499
genes like me logo Genes that share expression patterns with TEX22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX22 Gene

Orthologs for TEX22 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX22 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX22 35
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100855864 34
  • 79.68 (n)
TEX22 35
  • 67 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TEX22 34
  • 76.51 (n)
rat
(Rattus norvegicus)
Mammalia Tex22 34
  • 69.63 (n)
mouse
(Mus musculus)
Mammalia Tex22 17 35 34
  • 68.93 (n)
Species where no ortholog for TEX22 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX22 Gene

ENSEMBL:
Gene Tree for TEX22 (if available)
TreeFam:
Gene Tree for TEX22 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TEX22: view image

Paralogs for TEX22 Gene

Pseudogenes.org Pseudogenes for TEX22 Gene

genes like me logo Genes that share paralogs with TEX22: view

No data available for Paralogs for TEX22 Gene

Variants for TEX22 Gene

Sequence variations from dbSNP and Humsavar for TEX22 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000879303 -- 105,396,807(+) C/T upstream_transcript_variant
rs1000908816 -- 105,396,561(+) C/T upstream_transcript_variant
rs1001029210 -- 105,405,208(+) T/G intron_variant
rs1001290981 -- 105,401,560(+) C/T intron_variant
rs1001727493 -- 105,402,145(+) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TEX22 Gene

Variant ID Type Subtype PubMed ID
dgv3986n54 CNV loss 21841781
esv2760014 CNV loss 17122850
nsv1054190 CNV gain 25217958
nsv1160204 CNV duplication 26073780
nsv470679 CNV loss 18288195
nsv517055 CNV gain+loss 19592680
nsv566189 CNV gain 21841781
nsv566204 CNV gain 21841781
nsv566205 CNV loss 21841781
nsv817647 CNV gain 17921354
nsv832889 CNV loss 17160897
nsv832890 CNV loss 17160897
nsv952282 CNV deletion 24416366

Variation tolerance for TEX22 Gene

Gene Damage Index Score: 2.45; 43.10% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX22 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX22

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX22 Gene

Disorders for TEX22 Gene

Additional Disease Information for TEX22

No disorders were found for TEX22 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX22 Gene

Publications for TEX22 Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for TEX22 Gene

Sources for TEX22 Gene

Content
Loading form....