Aliases for TEX14 Gene
Aliases for TEX14 Gene
External Ids for TEX14 Gene
- HGNC: 11737
- Entrez Gene: 56155
- Ensembl: ENSG00000121101
- OMIM: 605792
- UniProtKB: Q8IWB6
Previous GeneCards Identifiers for TEX14 Gene
- GC17M056378
- GC17M059115
- GC17M056976
- GC17M057108
- GC17M053989
- GC17M056634
- GC17M051994
Summaries for TEX14 Gene
-
The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
GeneCards Summary for TEX14 Gene
TEX14 (Testis Expressed 14, Intercellular Bridge Forming Factor) is a Protein Coding gene. Diseases associated with TEX14 include Spermatogenic Failure 23. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.
UniProtKB/Swiss-Prot for TEX14 Gene
-
Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX14 Gene
Genomics for TEX14 Gene
GeneHancer (GH) Regulatory Elements for TEX14 Gene
Promoters and enhancers for TEX14 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TEX14 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TEX14 Gene
Genomic Locations for TEX14 Gene
- chr17:58,556,677-58,692,079
- (GRCh38/hg38)
- Size:
- 135,403 bases
- Orientation:
- Minus strand
- chr17:56,634,038-56,769,416
- (GRCh37/hg19)
Genomic View for TEX14 Gene
Genes around TEX14 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q22 by Ensembl
- 17q22 by Entrez Gene
- 17q22 by HGNC
TEX14 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TEX14 Gene
Proteins for TEX14 Gene
-
Protein details for TEX14 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IWB6-TEX14_HUMAN
- Recommended name:
- Inactive serine/threonine-protein kinase TEX14
- Protein Accession:
- Q8IWB6
- A6NH19
- Q7RTP3
- Q8ND97
- Q9BXT9
Protein attributes for TEX14 Gene
- Size:
- 1497 amino acids
- Molecular mass:
- 167901 Da
- Quaternary structure:
-
- Interacts with KIF23 and RBM44. Interacts with CEP55; inhibiting interaction between CEP55 and PDCD6IP/ALIX and TSG101 (By similarity).
- SequenceCaution:
-
- Sequence=AAK31980.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for TEX14 Gene
Post-translational modifications for TEX14 Gene
- Phosphorylated on Thr residues by CDK1 during early phases of mitosis, promoting the interaction with PLK1 and recruitment to kinetochores. Phosphorylated on Ser-437 by PLK1 during late prometaphase promotes the rapid depletion from kinetochores and its subsequent degradation by the APC/C complex.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for TEX14 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TEX14
-
Abcam antibodies for TEX14
- Invitrogen Antibodies for TEX14
- GeneTex TEX14 antibody for TEX14
-
Santa Cruz Biotechnology (SCBT) Antibodies for TEX14
Protein Products
-
OriGene Purified Proteins for TEX14
- Search Origene for MassSpec and Protein Over-expression Lysates for TEX14
- Origene Custom Protein Services for TEX14
- Novus Biologicals proteins for TEX14
- Search GeneTex for Proteins for TEX14
-
Abcam proteins for TEX14
Assay Products
No data available for DME Specific Peptides for TEX14 Gene
Domains & Families for TEX14 Gene
Gene Families for TEX14 Gene
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
- Transporters
Protein Domains for TEX14 Gene
Suggested Antigen Peptide Sequences for TEX14 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IWB6UniProtKB/Swiss-Prot:
TEX14_HUMAN :- The protein kinase domain is predicted to be catalytically inactive.
- Belongs to the protein kinase superfamily.
- Domain:
-
- The protein kinase domain is predicted to be catalytically inactive.
- The GPPX3Y motif mediates interaction with CEP55.
- Family:
-
- Belongs to the protein kinase superfamily.
Function for TEX14 Gene
Molecular function for TEX14 Gene
- UniProtKB/Swiss-Prot Function:
- Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity).
Phenotypes From GWAS Catalog for TEX14 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 20176808 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0019901 | protein kinase binding | IPI | 22405274 |
Phenotypes for TEX14 Gene
- MGI mutant phenotypes for TEX14:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TEX14:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Decreased hepcidin::fluc mRNA expression
- shRNA abundance <= 50%
- Increased transferrin (TF) endocytosis
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Increased cell death HMECs cells
- Weakly decreased NFAT1-GFP nuclear translocation
- Decreased cell proliferation
- Increased cell migration
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
Animal Models for TEX14 Gene
- MGI Knock Outs for TEX14:
-
- Tex14 tm1Zuk
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TEX14
-
-
ViGene Biosciences lentiviral particle packaged cDNA for TEX14 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TEX14 gene
- Search ViGene Biosciences for TEX14
CRISPR Products
-
OriGene CRISPR knockouts for TEX14
- genomics-online: gRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- Applied Biological Materials CRISPR for TEX14
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TEX14
- GenScript: Design CRISPR guide RNA sequences for TEX14
miRNA Products
- Search ViGene Biosciences for TEX14
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TEX14
- Browse OriGene Inhibitory RNA Products For TEX14
- genomics-online: shRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TEX14 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for TEX14
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TEX14
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TEX14
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TEX14
-
ViGene Biosciences adenoviral particle packaged cDNA for TEX14 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TEX14 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TEX14 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TEX14 Gene
Localization for TEX14 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TEX14 Gene
- Cytoplasm. Midbody. Chromosome, centromere, kinetochore. Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 2 |
| mitochondrion | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
- Cell Junctions (2)
- Cytosol (2)
- Plasma membrane (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IBA,ISS | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0005623 | cell | ISS | -- |
| GO:0005694 | chromosome | IEA | -- |
Pathways & Interactions for TEX14 Gene
No Data Available
Interacting Proteins for TEX14 Gene
Selected Interacting proteins:
ENSP00000240361
Q8IWB6-TEX14_HUMAN
for TEX14 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007094 | mitotic spindle assembly checkpoint | ISS | -- |
| GO:0007140 | male meiotic nuclear division | ISS,IBA | -- |
| GO:0008608 | attachment of spindle microtubules to kinetochore | IBA,ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for TEX14 Gene
Transcripts for TEX14 Gene
mRNA/cDNA for TEX14 Gene
- (6) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (37) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for TEX14
- genomics-online: gRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- Applied Biological Materials CRISPR for TEX14
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TEX14
- GenScript: Design CRISPR guide RNA sequences for TEX14
miRNA Products
- Search ViGene Biosciences for TEX14
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TEX14
- Browse OriGene Inhibitory RNA Products For TEX14
- genomics-online: shRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for TEX14 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for TEX14
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TEX14
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TEX14
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: |
| ExUns: | 22b | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||
| SP6: |
Expression for TEX14 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Gonad
- Primary Spermatocyte Seminiferous Tubules
- XX Germ Cells Ovigerous Cord
- XY Germ Cells Testis Cord
- Primordial germ-like cells(West JA et. al. 2006)
- Inner Cell Mass (Early Embryonic Tissues)
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
- Granulosa Cells Primary Follicle
- XX Germ Cells Ovigerous Cord
-
Testis (Reproductive System)
- Primary Spermatocyte Seminiferous Tubules
- XY Germ Cells Testis Cord
- Seminiferous Tubules
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
- Endothelial Cells Blood Brain Barrier
- Germ Cells (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for TEX14 Gene
This gene is overexpressed in Testis (x27.2).
This gene is overexpressed in Testis (31.9), Serum (14.5), Fetal Brain (10.3), and Ovary (9.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX14 Gene
NURSA nuclear receptor signaling pathways regulating expression of TEX14 Gene:
TEX14SOURCE GeneReport for Unigene cluster for TEX14 Gene:
Hs.390221mRNA Expression by UniProt/SwissProt for TEX14 Gene:
Q8IWB6-TEX14_HUMAN
Tissue specificity:
Expression restricted to testis.
Evidence on tissue expression from TISSUES for TEX14 Gene
- Nervous system(2.6)
Primer Products
-
OriGene qPCR primer pairs for TEX14
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX14 Gene
Orthologs for TEX14 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TEX14 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TEX14 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | TEX14 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tex14 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Tex14 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TEX14 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TEX14 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TEX14 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | TEX14 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | TEX14 34 |
|
OneToOne |
- Species where no ortholog for TEX14 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for TEX14 Gene
Pseudogenes.org Pseudogenes for TEX14 Gene
No data available for Paralogs for TEX14 Gene
Variants for TEX14 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000113630 | uncertain-significance, Hereditary cancer-predisposing syndrome | 58,692,732(-) | C/T | upstream_transcript_variant | |
| rs1057517641 | likely-pathogenic, Fanconi anemia, complementation group O, Breast-ovarian cancer, familial 3 | 58,692,790(-) | T/G | upstream_transcript_variant | |
| rs1060502587 | uncertain-significance, Fanconi anemia, complementation group O, Hereditary cancer-predisposing syndrome | 58,692,725(-) | G/A/C | upstream_transcript_variant | |
| rs1060502593 | uncertain-significance, Fanconi anemia, complementation group O | 58,692,687(-) | T/G | upstream_transcript_variant | |
| rs1060502603 | uncertain-significance, Fanconi anemia, complementation group O | 58,692,680(-) | G/C | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2657166 | CNV | deletion | 23128226 |
| esv2661744 | CNV | deletion | 23128226 |
| esv2671957 | CNV | deletion | 23128226 |
| esv2758698 | CNV | gain | 17122850 |
| esv3582847 | CNV | loss | 25503493 |
| esv3582848 | CNV | loss | 25503493 |
| esv3640889 | CNV | loss | 21293372 |
| esv3640891 | CNV | loss | 21293372 |
| nsv1066945 | CNV | loss | 25217958 |
| nsv1138560 | CNV | deletion | 24896259 |
| nsv1152637 | CNV | insertion | 26484159 |
| nsv428347 | CNV | gain | 18775914 |
| nsv457863 | CNV | loss | 19166990 |
| nsv477144 | CNV | novel sequence insertion | 20440878 |
| nsv515871 | CNV | loss | 19592680 |
| nsv575801 | CNV | loss | 21841781 |
| nsv833498 | CNV | loss | 17160897 |
| nsv962346 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
51.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.01;
60.24% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TEX14 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX14 Gene
Disorders for TEX14 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spermatogenic failure 23 |
|
Search TEX14 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TEX14_HUMAN- Spermatogenic failure 23 (SPGF23) [MIM:617707]: An infertility disorder caused by spermatogenesis defects that result in non-obstructive azoospermia. {ECO:0000269 PubMed:28206990}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for TEX14
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for TEX14 Gene
Publications for TEX14 Gene
- Sequence and expression of testis-expressed gene 14 (Tex14): a gene encoding a protein kinase preferentially expressed during spermatogenesis. (PMID: 12711554) Wu MH … Matzuk MM (Gene expression patterns : GEP 2003) 2 3 4 58
- An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang PJ … Page DC (Nature genetics 2001) 2 3 4 58
- Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells. (PMID: 26392564) Kim HJ … Lee HH (Proceedings of the National Academy of Sciences of the United States of America 2015) 2 3 58
- Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint. (PMID: 22405274) Mondal G … Couch FJ (Molecular cell 2012) 3 4 58
- Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. (PMID: 20378615) Aston KI … Carrell DT (Human reproduction (Oxford, England) 2010) 3 44 58
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- VectorBuilder custom plasmid, inducible vectors for TEX14
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TEX14
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 15 available TEX14 Antibodies ranked by validation data
- Compare Top TEX14 Antibodies
- antibodies-online: Search results for available TEX14 related products ranked by validation data
- antibodies-online: Search results for 3 available TEX14 Proteins ranked by validation data
- Compare Top TEX14 Proteins
- GeneTex TEX14 antibody for TEX14
- Search GeneTex for Proteins for TEX14
- ViGene Biosciences adenoviral particle packaged cDNA for TEX14 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TEX14 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TEX14 gene
- Search ViGene Biosciences for TEX14
- Santa Cruz Biotechnology (SCBT) Antibodies for TEX14
- Search Santa Cruz Biotechnology (SCBT) for TEX14 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TEX14
- Horizon Cell Lines for TEX14
- genomics-online: cdna clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- orf clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- genomics-online: gRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- genomics-online: primer clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
- genomics-online: shRNA clones - Search results for 76 available TEX14 gene related products
- Overview of 76 available TEX14 gene related products
Sources for TEX14 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
