This gene is similar to a mouse gene that is expressed in the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] See more...

Aliases for TEX13A Gene

Aliases for TEX13A Gene

  • Testis Expressed 13A 2 3 5
  • Testis-Expressed Protein 13A 3 4
  • Testis-Expressed Sequence 13A Protein 3
  • Testis Expressed Sequence 13A 2
  • TEX13A 5

External Ids for TEX13A Gene

Previous GeneCards Identifiers for TEX13A Gene

  • GC0XM099775
  • GC0XM101382
  • GC0XM102496
  • GC0XM103235
  • GC0XM104269
  • GC0XM104463
  • GC0XM094089

Summaries for TEX13A Gene

Entrez Gene Summary for TEX13A Gene

  • This gene is similar to a mouse gene that is expressed in the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

GeneCards Summary for TEX13A Gene

TEX13A (Testis Expressed 13A) is a Protein Coding gene. An important paralog of this gene is TEX13B.

Additional gene information for TEX13A Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TEX13A Gene

Genomics for TEX13A Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TEX13A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ105220 Promoter 0.4 EPDnew 600.7 0.0 -20 0.1 PRDM10 TEX13A KCTD9P2 NRK IL1RAPL2
GH0XJ105226 Enhancer 0.3 Ensembl ENCODE 0.4 -6.0 -6007 0.6 TEX13A KCTD9P2 NRK IL1RAPL2
GH0XJ105313 Enhancer 0.7 FANTOM5 ENCODE 0.2 -93.7 -93679 2.2 CEBPB JUN JUND EP300 STAT1 STAT3 TCF7L2 NFE2L2 FOS PWWP3B KCTD9P2 TEX13A NRK IL1RAPL2
GH0XJ105273 Enhancer 0.5 ENCODE 0.2 -53.0 -52976 0.8 CTBP1 ESRRA ZNF217 DPF2 SMARCE1 TEX13A KCTD9P2 NRK IL1RAPL2
GH0XJ105323 Enhancer 0.6 Ensembl 0.1 -103.5 -103543 0.7 CREB1 CTBP1 FOS RCOR1 ZNF217 JUND GATAD2B EP300 DPF2 SIX4 KCTD9P2 TEX13A NRK IL1RAPL2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TEX13A on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TEX13A

Top Transcription factor binding sites by QIAGEN in the TEX13A gene promoter:
  • aMEF-2
  • Cart-1
  • CP2
  • GATA-1
  • HNF-1
  • HNF-1A
  • LCR-F1
  • MEF-2A
  • Msx-1
  • Sox5

Genomic Locations for TEX13A Gene

Genomic Locations for TEX13A Gene
chrX:105,218,929-105,220,694
(GRCh38/hg38)
Size:
1,766 bases
Orientation:
Minus strand
chrX:104,463,611-104,465,358
(GRCh37/hg19)
Size:
1,748 bases
Orientation:
Minus strand

Genomic View for TEX13A Gene

Genes around TEX13A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX13A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX13A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX13A Gene

Proteins for TEX13A Gene

  • Protein details for TEX13A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BXU3-TX13A_HUMAN
    Recommended name:
    Testis-expressed protein 13A
    Protein Accession:
    Q9BXU3
    Secondary Accessions:
    • B1B1G8
    • Q32NB6

    Protein attributes for TEX13A Gene

    Size:
    409 amino acids
    Molecular mass:
    45583 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX13A Gene

Post-translational modifications for TEX13A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX13A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX13A Gene

Domains & Families for TEX13A Gene

Gene Families for TEX13A Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX13A Gene

InterPro:
Blocks:
  • Zn-finger, Ran-binding
ProtoNet:

Suggested Antigen Peptide Sequences for TEX13A Gene

GenScript: Design optimal peptide antigens:
  • Testis-expressed sequence 13A protein (TX13A_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9BXU3

UniProtKB/Swiss-Prot:

TX13A_HUMAN :
  • Belongs to the TEX13 family.
Family:
  • Belongs to the TEX13 family.
genes like me logo Genes that share domains with TEX13A: view

Function for TEX13A Gene

Gene Ontology (GO) - Molecular Function for TEX13A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TEX13A: view

Phenotypes for TEX13A Gene

genes like me logo Genes that share phenotypes with TEX13A: view

Animal Model Products

CRISPR Products

miRNA for TEX13A Gene

miRTarBase miRNAs that target TEX13A

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEX13A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX13A Gene

Localization for TEX13A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX13A gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TEX13A Gene

Pathways & Interactions for TEX13A Gene

PathCards logo

SuperPathways for TEX13A Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX13A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX13A Gene

Drugs & Compounds for TEX13A Gene

No Compound Related Data Available

Transcripts for TEX13A Gene

mRNA/cDNA for TEX13A Gene

2 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEX13A

Alternative Splicing Database (ASD) splice patterns (SP) for TEX13A Gene

No ASD Table

Relevant External Links for TEX13A Gene

GeneLoc Exon Structure for
TEX13A

Expression for TEX13A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TEX13A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX13A Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for TEX13A Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEX13A Gene



Protein tissue co-expression partners for TEX13A Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TEX13A

SOURCE GeneReport for Unigene cluster for TEX13A Gene:

Hs.567543

mRNA Expression by UniProt/SwissProt for TEX13A Gene:

Q9BXU3-TX13A_HUMAN
Tissue specificity: Testis specific.

Evidence on tissue expression from TISSUES for TEX13A Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with TEX13A: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX13A Gene

Orthologs for TEX13A Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX13A Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia TEX13A 30
  • 99.02 (n)
Dog
(Canis familiaris)
Mammalia LOC492058 30
  • 73.76 (n)
Cow
(Bos Taurus)
Mammalia TEX13B 30
  • 72.84 (n)
Mouse
(Mus musculus)
Mammalia Tex13a 30 17
  • 65.32 (n)
Rat
(Rattus norvegicus)
Mammalia Tex13a 30
  • 62.37 (n)
Species where no ortholog for TEX13A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TEX13A Gene

ENSEMBL:
Gene Tree for TEX13A (if available)
TreeFam:
Gene Tree for TEX13A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TEX13A: view image

Paralogs for TEX13A Gene

Paralogs for TEX13A Gene

(1) SIMAP similar genes for TEX13A Gene using alignment to 2 proteins:

  • TX13A_HUMAN
  • J3KPB0_HUMAN
genes like me logo Genes that share paralogs with TEX13A: view

Variants for TEX13A Gene

Additional dbSNP identifiers (rs#s) for TEX13A Gene

Variation tolerance for TEX13A Gene

Gene Damage Index Score: 0.58; 12.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TEX13A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX13A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for TEX13A Gene

Disorders for TEX13A Gene

No disorders were found for TEX13A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX13A Gene

Publications for TEX13A Gene

  1. An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang PJ … Page DC (Nature genetics 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3

Products for TEX13A Gene

Sources for TEX13A Gene