Aliases for TENM4 Gene
External Ids for TENM4 Gene
Previous HGNC Symbols for TENM4 Gene
Previous GeneCards Identifiers for TENM4 Gene
The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. [provided by RefSeq, Oct 2016]
GeneCards Summary for TENM4 Gene
TENM4 (Teneurin Transmembrane Protein 4) is a Protein Coding gene. Diseases associated with TENM4 include Tremor, Hereditary Essential, 5 and Tremor. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity. An important paralog of this gene is TENM3.
UniProtKB/Swiss-Prot Summary for TENM4 Gene
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS) (PubMed:26188006). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer (By similarity).