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Aliases for TEDDM1 Gene
Aliases for TEDDM1 Gene
External Ids for TEDDM1 Gene
- HGNC: 30233
- Entrez Gene: 127670
- Ensembl: ENSG00000203730
- UniProtKB: Q5T9Z0
Previous GeneCards Identifiers for TEDDM1 Gene
- GC01M179100
- GC01M180633
- GC01M153603
Summaries for TEDDM1 Gene
GeneCards Summary for TEDDM1 Gene
TEDDM1 (Transmembrane Epididymal Protein 1) is a Protein Coding gene. An important paralog of this gene is TMEM45A.
Additional gene information for TEDDM1 Gene
- HGNC(30233)
- Entrez Gene(127670)
- Ensembl(ENSG00000203730)
- UniProtKB(Q5T9Z0)
- Open Targets Platform(ENSG00000203730)
- Search for TEDDM1 at DataMed
- Search for TEDDM1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TEDDM1 Gene
Genomics for TEDDM1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TEDDM1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TEDDM1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TEDDM1
- Top Transcription factor binding sites by QIAGEN in the TEDDM1 gene promoter:
-
- AP-1
- ATF-2
- c-Jun
Genomic Locations for TEDDM1 Gene
Genomic Locations for TEDDM1 Gene
- chr1:182,398,117-182,400,667
- (GRCh38/hg38)
- Size:
- 2,551 bases
- Orientation:
- Minus strand
- chr1:182,367,252-182,369,751
- (GRCh37/hg19)
- Size:
- 2,500 bases
- Orientation:
- Minus strand
Genomic View for TEDDM1 Gene
Genes around TEDDM1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.3 by HGNC
- 1q25.3 by Entrez Gene
- 1q25.3 by Ensembl
TEDDM1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TEDDM1 Gene
Proteins for TEDDM1 Gene
-
Protein details for TEDDM1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5T9Z0-TEDM1_HUMAN
- Recommended name:
- Transmembrane epididymal protein 1
- Protein Accession:
- Q5T9Z0
- Q8IVJ0
Protein attributes for TEDDM1 Gene
- Size:
- 273 amino acids
- Molecular mass:
- 31315 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for TEDDM1 Gene
No Post-translational modifications
Other Protein References for TEDDM1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
Protein Products
-
OriGene Purified Proteins for TEDDM1
- Search Origene for MassSpec and Protein Over-expression Lysates for TEDDM1
- Origene Custom Protein Services for TEDDM1
No data available for DME Specific Peptides for TEDDM1 Gene
Domains & Families for TEDDM1 Gene
Gene Families for TEDDM1 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for TEDDM1 Gene
- GenScript: Design optimal peptide antigens:
-
- Human epididymis-specific protein 9 (TEDM1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5T9Z0- Family:
-
- Belongs to the TMEM45 family.
Function for TEDDM1 Gene
Phenotypes From GWAS Catalog for TEDDM1 Gene
Phenotypes for TEDDM1 Gene
- GenomeRNAi human phenotypes for TEDDM1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TEDDM1 - Select products 50% OFF >
- * TEDDM1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TEDDM1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TEDDM1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TEDDM1
miRNA for TEDDM1 Gene
- miRTarBase miRNAs that target TEDDM1
-
- hsa-miR-8071 (MIRT456363)
- hsa-miR-766-5p (MIRT456364)
- hsa-miR-6134 (MIRT456365)
- hsa-miR-7854-3p (MIRT456366)
- hsa-miR-4459 (MIRT456367)
- hsa-miR-1827 (MIRT763128)
- hsa-miR-203b-3p (MIRT763707)
- hsa-miR-4649-3p (MIRT770681)
- hsa-miR-4680-5p (MIRT770931)
- hsa-miR-4722-5p (MIRT771594)
- hsa-miR-4768-3p (MIRT772144)
- hsa-miR-6808-5p (MIRT779722)
- hsa-miR-6893-5p (MIRT781254)
- hsa-miR-7158-3p (MIRT781570)
- hsa-miR-940 (MIRT782947)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TEDDM1
- Browse OriGene Inhibitory RNA Products For TEDDM1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEDDM1
Clone Products
- Applied Biological Materials (abm): Clones for TEDDM1 - Select products 50% OFF >
- * TEDDM1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TEDDM1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TEDDM1
Cell Line Products
-
Horizon Cell Lines for TEDDM1
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEDDM1 Gene
Localization for TEDDM1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TEDDM1 Gene
- Membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 3 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TEDDM1 Gene
Transcripts for TEDDM1 Gene
mRNA/cDNA for TEDDM1 Gene
- 1 REFSEQ mRNAs :
- 2 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000367565 2551 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TEDDM1 - Select products 50% OFF >
- * TEDDM1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TEDDM1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TEDDM1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TEDDM1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TEDDM1
- Browse OriGene Inhibitory RNA Products For TEDDM1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEDDM1
Clone Products
- Applied Biological Materials (abm): Clones for TEDDM1 - Select products 50% OFF >
- * TEDDM1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TEDDM1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TEDDM1
Relevant External Links for TEDDM1 Gene
- GeneLoc Exon Structure for
- TEDDM1
Expression for TEDDM1 Gene
mRNA differential expression in normal tissues according to GTEx for TEDDM1 Gene
This gene is overexpressed in Testis (x7.3).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TEDDM1
SOURCE GeneReport for Unigene cluster for TEDDM1 Gene:
Hs.156977Primer Products
-
OriGene qPCR primer pairs for TEDDM1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEDDM1 Gene
Orthologs for TEDDM1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC469606 30 |
|
||
| TEDDM1 31 |
|
OneToOne | |||
| Mouse (Mus musculus) |
Mammalia | Gm5531 30 31 |
|
OneToMany | |
| Teddm1 31 |
|
OneToMany | |||
| Teddm1b 17 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | LOC684709 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | TEDDM1 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TEDDM1 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToOne |
- Species where no ortholog for TEDDM1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for TEDDM1 Gene
- ENSEMBL:
- Gene Tree for TEDDM1 (if available)
- TreeFam:
- Gene Tree for TEDDM1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TEDDM1: view image
Paralogs for TEDDM1 Gene
Pseudogenes.org Pseudogenes for TEDDM1 Gene
Variants for TEDDM1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TEDDM1 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs6674281 | - | p.Tyr130His |
Residual Variation Intolerance Score:
42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.59;
12.77% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TEDDM1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TEDDM1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEDDM1 Gene
Disorders for TEDDM1 Gene
Additional Disease Information for TEDDM1
No disorders were found for TEDDM1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEDDM1 Gene
Publications for TEDDM1 Gene
- Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. (PMID: 29987050) Xiao T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2018) 3
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4
ExternalLinks
Products for TEDDM1 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TEDDM1
- Search Origene for MassSpec and Protein Over-expression Lysates for TEDDM1
- Origene Custom Protein Services for TEDDM1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TEDDM1
- Browse OriGene Inhibitory RNA Products For TEDDM1
- OriGene qPCR primer pairs for TEDDM1
- OriGene CRISPR knockouts for TEDDM1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TEDDM1
- Sino Biological Human cDNA Clone for TEDDM1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- VectorBuilder Custom and pre-made DNA vectors for TEDDM1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TEDDM1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TEDDM1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TEDDM1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TEDDM1
- antibodies-online: Search results for available TEDDM1 related products ranked by validation data
- antibodies-online: Search results for available TEDDM1 related products ranked by validation data
- antibodies-online: Search results for available TEDDM1 related products ranked by validation data
- Horizon Cell Lines for TEDDM1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TEDDM1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TEDDM1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TEDDM1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TEDDM1
Sources for TEDDM1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB