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TEAD2 (TEA Domain Transcription Factor 2) is a Protein Coding gene. Diseases associated with TEAD2 include Sveinsson Chorioretinal Atrophy. Among its related pathways are Hippo signaling pathway - multiple species and Gene Expression. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is TEAD4.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA,IBA | 21873635 |
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
GO:0001085 | RNA polymerase II transcription factor binding | IBA | -- |
GO:0001223 | transcription coactivator binding | IPI | 20368466 |
GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000790 | nuclear chromatin | ISA | -- |
GO:0005634 | nucleus | IBA,NAS | 8702974 |
GO:0005654 | nucleoplasm | TAS | -- |
GO:0005667 | transcription factor complex | IBA | 21873635 |
GO:0005829 | cytosol | IDA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
2 | Gene Expression |
.48
|
|
3 | Metabolism |
.40
|
|
4 | Wnt / Hedgehog / Notch | ||
5 | Hippo signaling pathway |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001570 | vasculogenesis | IEA | -- |
GO:0001843 | neural tube closure | IEA | -- |
GO:0003143 | embryonic heart tube morphogenesis | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | NAS | 8702974 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | TAS | -- |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TEAD2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | TEAD2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | TEAD2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Tead2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Tead2 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | TEAD2 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | TEAD2 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | sd 31 32 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | egl-44 31 32 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TEC1 33 |
|
|
Disorder | Aliases | PubMed IDs |
---|---|---|
sveinsson chorioretinal atrophy |
|
|