Aliases for TDRG1 Gene

Subcategory (RNA class) for TDRG1 Gene


Quality Score for this RNA gene is


Aliases for TDRG1 Gene

  • Testis Development Related 1 2 3 5
  • Testis Development Related 1 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 532 2 3
  • Testis Development Related Protein 1 3
  • Testis Development-Related Protein 1 4
  • LincRNA-NR_024015 3
  • HSALNG0049949 169
  • NONHSAG043741 94
  • Lnc-DAAM2-9 170
  • LINC00532 3

External Ids for TDRG1 Gene

Previous GeneCards Identifiers for TDRG1 Gene

  • GC06P040456
  • GC06P040303
  • GC06P042877
  • GC06P043216
  • GC06P040862
  • GC06P040865
  • GC06P041274
  • GC06P041947
  • GC06P042597

Summaries for TDRG1 Gene

GeneCards Summary for TDRG1 Gene

TDRG1 (Testis Development Related 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TDRG1 include Testicular Cancer and Microinvasive Gastric Cancer.

Additional gene information for TDRG1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TDRG1 Gene

Genomics for TDRG1 Gene

GeneHancer (GH) Regulatory Elements for TDRG1 Gene

Promoters and enhancers for TDRG1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J040287 Enhancer 0.2 Ensembl 750.6 +1.9 1863 0.5 TDRG1 piR-48965-120
GH06J040285 Enhancer 0.2 ENCODE 750.6 +0.3 295 1.4 TDRG1 piR-48965-120
GH06J040395 Enhancer 1 Ensembl ENCODE 12.5 +111.0 111014 3.2 TCF7L2 ZNF217 HLF MNT SP1 NCOA3 MYC FOSL2 CREB1 RXRA TDRG1 RF00026-931 RNU6-250P LINC00951 LRFN2
GH06J040387 Enhancer 0.6 FANTOM5 Ensembl ENCODE 13.9 +103.4 103414 6 ZMYM3 TDRG1 LINC00951 RF00026-931 RNU6-250P LRFN2
GH06J040398 Enhancer 0.5 ENCODE 13.2 +113.3 113270 0.2 HCFC1 ZNF217 SUZ12 ETS1 ZNF143 SIN3A THAP11 TDRG1 RF00026-931 RNU6-250P LINC00951 LRFN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TDRG1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TDRG1 gene promoter:
  • AP-2rep
  • c-Myb
  • E47
  • GATA-1
  • Hand1
  • POU2F1
  • POU2F1a
  • STAT1
  • TBP

Genomic Locations for TDRG1 Gene

Genomic Locations for TDRG1 Gene
101,804 bases
Plus strand
44,939 bases
Plus strand

Genomic View for TDRG1 Gene

Genes around TDRG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TDRG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TDRG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TDRG1 Gene

Proteins for TDRG1 Gene

  • Protein details for TDRG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis development-related protein 1
    Protein Accession:

    Protein attributes for TDRG1 Gene

    100 amino acids
    Molecular mass:
    10472 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TDRG1 Gene

Post-translational modifications for TDRG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TDRG1 Gene

Domains & Families for TDRG1 Gene

Gene Families for TDRG1 Gene

Protein Domains for TDRG1 Gene


Suggested Antigen Peptide Sequences for TDRG1 Gene

GenScript: Design optimal peptide antigens:
  • Testis development related protein 1 (Q3Y452_HUMAN)
genes like me logo Genes that share domains with TDRG1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TDRG1 Gene

Function for TDRG1 Gene

Phenotypes From GWAS Catalog for TDRG1 Gene

Phenotypes for TDRG1 Gene

genes like me logo Genes that share phenotypes with TDRG1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TDRG1 Gene

Localization for TDRG1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TDRG1 Gene


No data available for Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TDRG1 Gene

Pathways & Interactions for TDRG1 Gene

PathCards logo

SuperPathways for TDRG1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TDRG1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TDRG1 Gene

Drugs & Compounds for TDRG1 Gene

No Compound Related Data Available

Transcripts for TDRG1 Gene

mRNA/cDNA for TDRG1 Gene

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TDRG1 Gene

No ASD Table

Relevant External Links for TDRG1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TDRG1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TDRG1 Gene

mRNA differential expression in normal tissues according to GTEx for TDRG1 Gene

This gene is overexpressed in Testis (x45.5).

NURSA nuclear receptor signaling pathways regulating expression of TDRG1 Gene:


SOURCE GeneReport for Unigene cluster for TDRG1 Gene:


mRNA Expression by UniProt/SwissProt for TDRG1 Gene:

Tissue specificity: Expressed in the testis but not in any other non-reproductive tissues (at protein level). Mainly located in spermatogenic cells in seminiferous tubules of adult testis.
genes like me logo Genes that share expression patterns with TDRG1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TDRG1 Gene

Orthologs for TDRG1 Gene

Evolution for TDRG1 Gene

Gene Tree for TDRG1 (if available)
Gene Tree for TDRG1 (if available)

No data available for Orthologs for TDRG1 Gene

Paralogs for TDRG1 Gene

No data available for Paralogs for TDRG1 Gene

Variants for TDRG1 Gene

Sequence variations from dbSNP and Humsavar for TDRG1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1001232168 -- 40,377,004(+) C/A upstream_transcript_variant
rs1001650817 -- 40,376,380(+) C/T upstream_transcript_variant
rs1001683674 -- 40,376,673(+) C/A upstream_transcript_variant
rs1001896246 -- 40,377,591(+) T/C upstream_transcript_variant
rs1001948590 -- 40,377,324(+) T/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TDRG1 Gene

Variant ID Type Subtype PubMed ID
esv2763989 CNV loss 21179565
nsv5273 CNV deletion 18451855

Additional Variant Information for TDRG1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TDRG1 Gene

Disorders for TDRG1 Gene

MalaCards: The human disease database

(4) MalaCards diseases for TDRG1 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
testicular cancer
  • childhood neoplasm of the testis
microinvasive gastric cancer
  • early gastric cancer
aplastic anemia
  • aa
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search TDRG1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TDRG1

genes like me logo Genes that share disorders with TDRG1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TDRG1 Gene

Publications for TDRG1 Gene

  1. Characterization of a novel human testis-specific gene: testis developmental related gene 1 (TDRG1). (PMID: 22123530) Jiang X … Tang Y (The Tohoku journal of experimental medicine 2011) 2 3 4 56
  2. The has-miR-526b binding-site rs8506G>a polymorphism in the lincRNA-NR_024015 exon identified by GWASs predispose to non-cardia gastric cancer risk. (PMID: 24595048) Fan QH … Zhang LY (PloS one 2014) 2 3 56
  3. The role of the long non-coding RNA TDRG1 in epithelial ovarian carcinoma tumorigenesis and progression through miR-93/RhoC pathway. (PMID: 28984384) Chen S … Zhao Y (Molecular carcinogenesis 2018) 3 56
  4. LncRNA TDRG1 enhances tumorigenicity in endometrial carcinoma by binding and targeting VEGF-A protein. (PMID: 29920344) Chen S … Zhao Y (Biochimica et biophysica acta. Molecular basis of disease 2018) 3 56
  5. Potential lncRNA diagnostic biomarkers for early gastric cancer. (PMID: 29039538) Lu Q … Chen X (Molecular medicine reports 2017) 3 56

Products for TDRG1 Gene

Sources for TDRG1 Gene