Aliases for TCF25 Gene
External Ids for TCF25 Gene
Previous GeneCards Identifiers for TCF25 Gene
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008]
GeneCards Summary for TCF25 Gene
TCF25 (Transcription Factor 25) is a Protein Coding gene. Diseases associated with TCF25 include Toe Syndactyly, Telecanthus, And Anogenital And Renal Malformations and Vulvovaginitis. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity.
UniProtKB/Swiss-Prot Summary for TCF25 Gene
May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.