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TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008... See more...
Aliases for TCF21 Gene
Aliases for TCF21 Gene
External Ids for TCF21 Gene
- HGNC: 11632
- Entrez Gene: 6943
- Ensembl: ENSG00000118526
- OMIM: 603306
- UniProtKB: O43680
Previous GeneCards Identifiers for TCF21 Gene
- GC06P133833
- GC06P134057
- GC06P134190
- GC06P134251
- GC06P131779
Summaries for TCF21 Gene
-
TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TCF21 Gene
TCF21 (Transcription Factor 21) is a Protein Coding gene. Diseases associated with TCF21 include Uterine Corpus Endometrial Carcinoma and Pericoronitis. Among its related pathways are ERK Signaling and Human Embryonic Stem Cell Pluripotency. Gene Ontology (GO) annotations related to this gene include protein dimerization activity and proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific. An important paralog of this gene is MSC.
UniProtKB/Swiss-Prot Summary for TCF21 Gene
-
Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.
Additional gene information for TCF21 Gene
- HGNC(11632)
- Entrez Gene(6943)
- Ensembl(ENSG00000118526)
- OMIM(603306)
- UniProtKB(O43680)
- Open Targets Platform(ENSG00000118526)
- Monarch Initiative
- Search for TCF21 at DataMed
- Search for TCF21 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TCF21 Gene
Genomics for TCF21 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TCF21 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TCF21 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TCF21
- Top Transcription factor binding sites by QIAGEN in the TCF21 gene promoter:
-
- MyoD
- NF-kappaB
- NF-kappaB1
Genomic Locations for TCF21 Gene
Genomic Locations for TCF21 Gene
- chr6:133,889,113-133,895,553
- (GRCh38/hg38)
- Size:
- 6,441 bases
- Orientation:
- Plus strand
- chr6:134,210,259-134,216,691
- (GRCh37/hg19)
- Size:
- 6,433 bases
- Orientation:
- Plus strand
Genomic View for TCF21 Gene
Genes around TCF21 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q23.2 by HGNC
- 6q23.2 by Entrez Gene
- 6q23.2 by Ensembl
TCF21 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TCF21 Gene
Proteins for TCF21 Gene
-
Protein details for TCF21 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43680-TCF21_HUMAN
- Recommended name:
- Transcription factor 21
- Protein Accession:
- O43680
- E1P581
- O43545
- Q6ICV0
- Q9BZ14
Protein attributes for TCF21 Gene
- Size:
- 179 amino acids
- Molecular mass:
- 19715 Da
- Quaternary structure:
-
- Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3 and binds the E box (5'-CANNTG-3').
Post-translational modifications for TCF21 Gene
Other Protein References for TCF21 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences TCF21 / Epicardin Antibody
- Novus Biologicals Antibodies for TCF21
-
Abcam antibodies for TCF21
- Invitrogen Antibodies for TCF21 (AFLGC-TCF21)
-
Santa Cruz Biotechnology (SCBT) Antibodies for TCF21
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for TCF21
- Origene Custom Protein Services for TCF21
-
Signalway Proteins for TCF21
-
Abcam proteins for TCF21
Assay Products
- antibodies-online: Show 9 available TCF21 Elisa Kits ranked by validation data
- Compare Top TCF21 Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for TCF21
No data available for DME Specific Peptides for TCF21 Gene
Domains & Families for TCF21 Gene
Gene Families for TCF21 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transcription factors
Protein Domains for TCF21 Gene
- InterPro:
- Blocks:
-
- Basic helix-loop-helix dimerization domain bHLH
- ProtoNet:
Suggested Antigen Peptide Sequences for TCF21 Gene
- GenScript: Design optimal peptide antigens:
-
- Podocyte-expressed 1 (TCF21_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TCF21 Gene
Function for TCF21 Gene
Molecular function for TCF21 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.
- GENATLAS Biochemistry:
- transcription factor 21,murine Pod-1 homolog,mesoderm specific,expressed in mesenchymal and glomerular epithelial cells in the developing kidney
Phenotypes From GWAS Catalog for TCF21 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IBA | 21873635 |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IDA | 12493738 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | ISS | -- |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for TCF21 Gene
- MGI mutant phenotypes for TCF21:
-
inferred from 6 alleles
- immune system phenotype
- respiratory system phenotype
- normal phenotype
- cardiovascular system phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- renal/urinary system phenotype
- neoplasm
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- hematopoietic system phenotype
- integument phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for TCF21:
Animal Models for TCF21 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TCF21 - Select products 50% OFF >
- * TCF21 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for TCF21
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TCF21
-
Santa Cruz Biotechnology (SCBT) CRISPR for TCF21
miRNA for TCF21 Gene
- miRTarBase miRNAs that target TCF21
-
- hsa-miR-492 (MIRT006075)
- hsa-miR-21-5p (MIRT007085)
- hsa-miR-181a-5p (MIRT025053)
- hsa-miR-6735-3p (MIRT492081)
- hsa-miR-4721 (MIRT492082)
- hsa-miR-2467-3p (MIRT492083)
- hsa-miR-7107-5p (MIRT492084)
- hsa-miR-1234-3p (MIRT492085)
- hsa-miR-5088-5p (MIRT492086)
- mmu-miR-369-3p (MIRT577581)
- mmu-miR-374b-5p (MIRT577582)
- mmu-miR-410-3p (MIRT577583)
- mmu-miR-344d-3p (MIRT577584)
- mmu-miR-344e-3p (MIRT577585)
- mmu-miR-466p-3p (MIRT577586)
- mmu-miR-466b-3p (MIRT577587)
- mmu-miR-466c-3p (MIRT577588)
Targeted motifs for TCF21 Gene
HOMER Transcription Factor Regulatory Elements motif TCF21
- Consensus sequence: NAACAGCTGG Submotif: canonical Cell Type: ArterySmoothMuscle GEO ID: GSE61369
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TCF21
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Clone Products
- Applied Biological Materials (abm): Clones for TCF21 - Select products 50% OFF >
- * TCF21 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TCF21
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TCF21
Cell Line Products
-
Horizon Cell Lines for TCF21
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and Transcription Factor Targets for TCF21 Gene
Localization for TCF21 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TCF21 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA,IDA | 12493738 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TCF21 Gene
Pathways & Interactions for TCF21 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Human Embryonic Stem Cell Pluripotency |
Factors Promoting Cardiogenesis in Vertebrates
.50
|
Human Embryonic Stem Cell Pluripotency
.50
|
| 2 | ERK Signaling |
MAPK Signaling
.58
|
ILK Signaling
.49
|
| 3 | Regulation of activated PAK-2p34 by proteasome mediated degradation | ||
| 4 | Non-Canonical Wnt Pathway | ||
| 5 | PAK Pathway |
Epithelial Adherens Junctions
.36
|
|
Pathways by source for TCF21 Gene
2 Sino Biological pathways for TCF21 Gene
7 Qiagen pathways for TCF21 Gene
- Epithelial Adherens Junctions
- Factors Promoting Cardiogenesis in Vertebrates
- Human Embryonic Stem Cell Pluripotency
- ILK Signaling
- JNK Pathway
Interacting Proteins for TCF21 Gene
Selected Interacting proteins:
O43680-TCF21_HUMAN
ENSP00000356857
for TCF21 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TCF21
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IDA | 12493738 |
| GO:0001657 | ureteric bud development | ISS | -- |
| GO:0001658 | branching involved in ureteric bud morphogenesis | ISS | -- |
| GO:0001763 | morphogenesis of a branching structure | ISS | -- |
| GO:0001822 | kidney development | ISS | -- |
No data available for SIGNOR curated interactions for TCF21 Gene
Transcripts for TCF21 Gene
mRNA/cDNA for TCF21 Gene
- 2 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000237316 3010 nts (view in UCSC)
- ENST00000367882 1280 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TCF21 - Select products 50% OFF >
- * TCF21 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TCF21
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TCF21
-
Santa Cruz Biotechnology (SCBT) CRISPR for TCF21
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TCF21
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TCF21
Clone Products
- Applied Biological Materials (abm): Clones for TCF21 - Select products 50% OFF >
- * TCF21 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TCF21
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TCF21
Relevant External Links for TCF21 Gene
- GeneLoc Exon Structure for
- TCF21
Expression for TCF21 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Paraxial Mesoderm Cells Branchial Arch 2
- Mononuclear Myocytes Hyoid Arch Muscles
- Muscle satellite Cells Extraocular Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
- Paraxial Mesoderm Cells Branchial Arch 1
-
Kidney (Urinary System)
- Interstitial Stroma Cells Interstitial Stroma
- Cap Mesenchyme Cells Cap Mesenchyme
- Medullary Stroma Cells Interstitial Stroma
- S-shaped Body
- Interstitial Stroma
-
Adipose (Muscoskeletal System)
- Visceral White Preadipocytes Visceral White Adipose
- Subcutaneous White Preadipocytes Body Subcutaneous White Adipose
- Mesenchymal Stem Cells Subcutaneous White Adipose
- Visceral White Adipose
-
Heart (Cardiovascular System)
- Epicardial Progenitors Cells Epicardium
- Proepicardial Progenitor cells Proepicardium
- Endocardial Cells Endocardium
- Vascular Smooth Muscle Cells Coronary Capillary Plexus
-
Head Mesenchyme (Muscoskeletal System)
- Paraxial Mesoderm Cells Branchial Arch 2
- Paraxial Mesoderm Cells Branchial Arch 1
- Paraxial Mesoderm Cells Head Mesenchyme
-
Lung (Respiratory System)
- Distal Mesodermal Progenitor Cells Lung Mesoderm
- Early Lung Mesoderm Cells Lung Mesoderm
- Alveolar type II cells(Wade KC et. al. 2006)
-
Bone (Muscoskeletal System)
- Paraxial Mesoderm Cells Branchial Arch 1
- Paraxial Mesoderm Cells Head Mesenchyme
- Mandibular Process
-
Lateral Plate Mesoderm (Gastrulation Derivatives)
- Proepicardial Progenitor cells Proepicardium
- Coelomic Epithelial Cells Intraembryonic Coelom
- PureStem SM30, NCr-fac & Meso-latp Progenitor
-
Mesoderm (Gastrulation Derivatives)
- Septum Transversum Mesenchyme Cells Septum Transversum
- Septum Transversum
-
Ovary (Reproductive System)
- Ovarian Mesenchymal Stroma Cells Ovary Interstitium
-
Testis (Reproductive System)
- Testicular Interstitial Cells Testis Interstitium
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Subcutaneous White Adipose
-
Epithelial Cells
- Coelomic Epithelial Cells Intraembryonic Coelom
-
Gonad
- Coelomic Epithelial Cells Intraembryonic Coelom
-
Smooth Muscle (Muscoskeletal System)
- Vascular Smooth Muscle Cells Coronary Capillary Plexus
- Neural Crest (Gastrulation Derivatives)
- NULL (Uncategorized)
mRNA differential expression in normal tissues according to GTEx for TCF21 Gene
This gene is overexpressed in Lung (x7.6), Ovary (x6.3), Spleen (x4.7), and Kidney - Cortex (x4.1).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TCF21
SOURCE GeneReport for Unigene cluster for TCF21 Gene:
Hs.78061Evidence on tissue expression from TISSUES for TCF21 Gene
- Pancreas(4.4)
- Kidney(3.2)
- Lung(3)
- Heart(2.9)
- Intestine(2.9)
- Muscle(2.8)
- Skin(2.7)
- Spleen(2.6)
- Blood(2.6)
- Liver(2.5)
- Nervous system(2.3)
- Urine(2)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs for TCF21
-
OriGene qPCR primer pairs and template standards for TCF21
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TCF21 Gene
Orthologs for TCF21 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TCF21 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TCF21 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TCF21 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TCF21 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tcf21 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Tcf21 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TCF21 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TCF21 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TCF21 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tcf21 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | tcf21 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | HLH54F 31 |
|
OneToMany |
- Species where no ortholog for TCF21 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TCF21 Gene
- ENSEMBL:
- Gene Tree for TCF21 (if available)
- TreeFam:
- Gene Tree for TCF21 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TCF21: view image
Paralogs for TCF21 Gene
Variants for TCF21 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TCF21 Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 731660 | Benign: not provided | 133,889,838(+) | G/T | SYNONYMOUS_VARIANT | |
| 769693 | Benign: not provided | 133,889,667(+) | C/T | SYNONYMOUS_VARIANT | |
| rs61729591 | Uncertain Significance: not provided | 133,889,460(+) | C/G | MISSENSE_VARIANT |
Residual Variation Intolerance Score:
51.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.51;
64.63% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TCF21 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCF21 Gene
Disorders for TCF21 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| uterine corpus endometrial carcinoma |
|
|
| pericoronitis |
|
|
| paralytic ileus |
|
|
| subacute lymphocytic thyroiditis |
|
|
| pain agnosia |
|
|
Search TCF21 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TCF21
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TCF21 Gene
Publications for TCF21 Gene
- epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. (PMID: 9733105) Robb L … Harvey RP (Developmental dynamics : an official publication of the American Association of Anatomists 1998) 3 4 23
- Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney. (PMID: 9507058) Quaggin SE … Igarashi P (Mechanisms of development 1998) 2 3 23
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. (PMID: 21378990) Schunkert H … Samani NJ (Nature genetics 2011) 3 41
- Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A … Murray JC (PloS one 2010) 3 41
- Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PMID: 18978678) Vieira AR … Marazita ML (Genetics in medicine : official journal of the American College of Medical Genetics 2008) 3 41
ExternalLinks
Products for TCF21 Gene
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- Browse Primary Antibodies
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- Invitrogen Antibodies for TCF21 (AFLGC-TCF21)
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- antibodies-online: Show 9 available TCF21 Antibodies ranked by validation data
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- antibodies-online: Show 9 available TCF21 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 8 available TCF21 Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for TCF21
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Sources for TCF21 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB