Aliases for TCEAL1 Gene
External Ids for TCEAL1 Gene
Previous GeneCards Identifiers for TCEAL1 Gene
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
GeneCards Summary for TCEAL1 Gene
TCEAL1 (Transcription Elongation Factor A Like 1) is a Protein Coding gene. Diseases associated with TCEAL1 include Plasmodium Ovale Malaria. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TCEAL8.
UniProtKB/Swiss-Prot Summary for TCEAL1 Gene
May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.