This pseudogene is located downstream from the growth hormone locus on chromosome 17. This locus evolved by a series of partial duplications that have disrupted the human gene. A homologous gene in mouse encodes a testis-specific cell adhesion protein that may play a role in germ cell-Sertoli cell interactions. [provided by RefSeq, Apr 2012] See more...

Aliases for TCAM1P Gene

Aliases for TCAM1P Gene

  • Testicular Cell Adhesion Molecule 1, Pseudogene 2 3 5
  • Testicular Cell Adhesion Molecule 1 Homolog (Mouse), Pseudogene 2
  • Testicular Cell Adhesion Molecule 1 Homolog, Pseudogene 3
  • Testicular Cell Adhesion Molecule 1 Homolog (Mouse) 2
  • TCAM1P 5
  • TCAM1 3

External Ids for TCAM1P Gene

Previous HGNC Symbols for TCAM1P Gene

  • TCAM1

Previous GeneCards Identifiers for TCAM1P Gene

  • GC17P061927

Summaries for TCAM1P Gene

Entrez Gene Summary for TCAM1P Gene

  • This pseudogene is located downstream from the growth hormone locus on chromosome 17. This locus evolved by a series of partial duplications that have disrupted the human gene. A homologous gene in mouse encodes a testis-specific cell adhesion protein that may play a role in germ cell-Sertoli cell interactions. [provided by RefSeq, Apr 2012]

GeneCards Summary for TCAM1P Gene

TCAM1P (Testicular Cell Adhesion Molecule 1, Pseudogene) is a Pseudogene.

Additional gene information for TCAM1P Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TCAM1P Gene

Genomics for TCAM1P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TCAM1P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J063848 Promoter/Enhancer 1.8 Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 -0.1 -100 1.5 SP1 ZNF207 NCOR1 MYC IKZF1 SIX5 ZNF592 BRCA1 NONO CTCF lnc-PSMC5-7 TCAM1P DDX42 FTSJ3 CEP95 CSH2 POLG2 DDX5 SMARCD2 EEF1DP7
GH17J063600 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 9.9 -248.0 -248016 2.5 BCLAF1 SP1 ZNF654 ZNF207 MYC ZNF600 SIX5 SSRP1 ZNF580 ZMYM3 NONHSAG022459.2 TACO1 POLG2 CEP95 FTSJ3 DDX42 DDX5 SMARCD2 DCAF7 MAP3K3
GH17J063694 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 6.1 -150.0 -150021 10.2 BCLAF1 SP1 ZNF207 ZNF654 ZNF600 POLR2A CEBPA ZIC2 ZBTB10 CTCF STRADA ENSG00000279369 LIMD2 LOC729683 lnc-CCDC47-2 piR-33059 FTSJ3 CSH2 ENSG00000125695 PSMC5
GH17J063355 Enhancer 0.9 Ensembl ENCODE 4.5 -491.7 -491691 3.6 JUND ZNF10 ZIC2 FEZF1 MAFF ZNF316 ZNF843 MAFK PRDM6 MAFG CYB561 TCAM1P LOC105371857 ENSG00000271749 TANC2
GH17J063439 Promoter/Enhancer 0.7 Ensembl dbSUPER 4.9 -411.0 -410991 0.6 ZBTB33 KLF1 ESRRA piR-51111 TCAM1P CYB561 lnc-STRADA-4 TANC2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TCAM1P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TCAM1P Gene

Latest Assembly
chr17:63,849,292-63,864,379
(GRCh38/hg38)
Size:
15,088 bases
Orientation:
Plus strand

Previous Assembly
chr17:61,934,376-61,941,739
(GRCh37/hg19 by Entrez Gene)
Size:
7,364 bases
Orientation:
Plus strand

chr17:61,926,652-61,941,739
(GRCh37/hg19 by Ensembl)
Size:
15,088 bases
Orientation:
Plus strand

Genomic View for TCAM1P Gene

Genes around TCAM1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCAM1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCAM1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCAM1P Gene

Proteins for TCAM1P Gene

Post-translational modifications for TCAM1P Gene

No Post-translational modifications

No data available for DME Specific Peptides for TCAM1P Gene

Domains & Families for TCAM1P Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TCAM1P Gene

Function for TCAM1P Gene

Phenotypes From GWAS Catalog for TCAM1P Gene

miRNA for TCAM1P Gene

miRTarBase miRNAs that target TCAM1P

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TCAM1P Gene

Localization for TCAM1P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TCAM1P Gene

Pathways & Interactions for TCAM1P Gene

PathCards logo

SuperPathways for TCAM1P Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCAM1P Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TCAM1P Gene

Drugs & Compounds for TCAM1P Gene

No Compound Related Data Available

Transcripts for TCAM1P Gene

mRNA/cDNA for TCAM1P Gene

7 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TCAM1P Gene

No ASD Table

Relevant External Links for TCAM1P Gene

GeneLoc Exon Structure for
TCAM1P

Expression for TCAM1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TCAM1P Gene

mRNA differential expression in normal tissues according to GTEx for TCAM1P Gene

This gene is overexpressed in Testis (x39.7).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TCAM1P

SOURCE GeneReport for Unigene cluster for TCAM1P Gene:

Hs.629177
genes like me logo Genes that share expression patterns with TCAM1P: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TCAM1P Gene

Orthologs for TCAM1P Gene

Evolution for TCAM1P Gene

ENSEMBL:
Gene Tree for TCAM1P (if available)
TreeFam:
Gene Tree for TCAM1P (if available)
Alliance of Genome Resources:
Additional Orthologs for TCAM1P

No data available for Orthologs for TCAM1P Gene

Paralogs for TCAM1P Gene

No data available for Paralogs for TCAM1P Gene

Variants for TCAM1P Gene

Structural Variations from Database of Genomic Variants (DGV) for TCAM1P Gene

Variant ID Type Subtype PubMed ID
esv2716098 CNV deletion 23290073
esv3573787 CNV gain 25503493
esv3582856 CNV loss 25503493
nsv510720 CNV deletion 20534489
nsv517272 CNV gain+loss 19592680
nsv833510 CNV loss 17160897
nsv954553 CNV deletion 24416366
nsv960135 CNV duplication 23825009

Additional Variant Information for TCAM1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TCAM1P
Leiden Open Variation Database (LOVD)
TCAM1P

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance and Variation tolerance for TCAM1P Gene

Disorders for TCAM1P Gene

Additional Disease Information for TCAM1P

No disorders were found for TCAM1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCAM1P Gene

Publications for TCAM1P Gene

  1. Testicular cell adhesion molecule 1 (TCAM1) is not essential for fertility. (PMID: 19766163) Nalam RL … Matzuk MM (Molecular and cellular endocrinology 2010) 2 3
  2. Structure, expression, and conserved physical linkage of mouse testicular cell adhesion molecule-1 (TCAM-1) gene. (PMID: 11195349) Sakatani S … Ono M (Genome 2000) 2 3
  3. The human growth hormone locus: nucleotide sequence, biology, and evolution. (PMID: 2744760) Chen EY … Seeburg PH (Genomics 1989) 2 3
  4. Characterization of the human TCAM1P pseudogene and its activation by a potential dual promoter-enhancer: comparison with a protein-coding mouse orthologue. (PMID: 25622893) Kurihara M … Kimura AP (FEBS letters 2015) 3
  5. Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. (PMID: 20210993) Zhang ZD … Gerstein M (Genome biology 2010) 3

Products for TCAM1P Gene

Sources for TCAM1P Gene