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This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008] See more...
Aliases for TBX6 Gene
Aliases for TBX6 Gene
External Ids for TBX6 Gene
- HGNC: 11605
- Entrez Gene: 6911
- Ensembl: ENSG00000149922
- OMIM: 602427
- UniProtKB: O95947
Previous GeneCards Identifiers for TBX6 Gene
- GC16P029057
- GC16M030419
- GC16M030095
- GC16M030134
- GC16M030004
- GC16M030097
- GC16M027758
Summaries for TBX6 Gene
-
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008]
GeneCards Summary for TBX6 Gene
TBX6 (T-Box Transcription Factor 6) is a Protein Coding gene. Diseases associated with TBX6 include Spondylocostal Dysostosis 5 and Scoliosis. Among its related pathways are Gene regulatory network modelling somitogenesis and Neural Crest Differentiation. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II activating transcription factor binding. An important paralog of this gene is TBX3.
UniProtKB/Swiss-Prot Summary for TBX6 Gene
-
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
Additional gene information for TBX6 Gene
- HGNC(11605)
- Entrez Gene(6911)
- Ensembl(ENSG00000149922)
- OMIM(602427)
- UniProtKB(O95947)
- Open Targets Platform(ENSG00000149922)
- Monarch Initiative
- Search for TBX6 at DataMed
- Search for TBX6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TBX6 Gene
Genomics for TBX6 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TBX6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TBX6 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TBX6
- Top Transcription factor binding sites by QIAGEN in the TBX6 gene promoter:
-
- Nkx2-5
Genomic Locations for TBX6 Gene
Genomic Locations for TBX6 Gene
- chr16:30,085,793-30,091,927
- (GRCh38/hg38)
- Size:
- 6,135 bases
- Orientation:
- Minus strand
- chr16:30,097,114-30,103,208
- (GRCh37/hg19)
- Size:
- 6,095 bases
- Orientation:
- Minus strand
Genomic View for TBX6 Gene
Genes around TBX6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
TBX6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TBX6 Gene
Proteins for TBX6 Gene
-
Protein details for TBX6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95947-TBX6_HUMAN
- Recommended name:
- T-box transcription factor TBX6
- Protein Accession:
- O95947
- Q8TAS4
- Q9HA44
Protein attributes for TBX6 Gene
- Size:
- 436 amino acids
- Molecular mass:
- 47045 Da
- Quaternary structure:
-
- Forms a dimeric complex with DNA (in vitro).
Post-translational modifications for TBX6 Gene
Other Protein References for TBX6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences TBX6 Antibody
-
Custom Antibody ServicesOriGene Antibodies for TBX6
- Novus Biologicals Antibodies for TBX6
-
Abcam antibodies for TBX6
- Invitrogen Antibodies for TBX6 (AFLGC-TBX6)
-
Boster Bio Antibodies for TBX6
-
Santa Cruz Biotechnology (SCBT) Antibodies for TBX6
- Sino Biological Antibodies for TBX6
Protein Products
-
OriGene Purified Proteins for TBX6
- Search Origene for MassSpec and Protein Over-expression Lysates for TBX6
- Origene Custom Protein Services for TBX6
- antibodies-online: Show 4 available TBX6 Proteins ranked by validation data
- Compare Top TBX6 Proteins
-
Quality Products:
-
Signalway Proteins for TBX6
-
Abcam proteins for TBX6
No data available for DME Specific Peptides for TBX6 Gene
Domains & Families for TBX6 Gene
Gene Families for TBX6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Transcription factors
Protein Domains for TBX6 Gene
- InterPro:
- Blocks:
-
- Transcription factor, T-box
- Brachyury protein family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for TBX6 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ12268 fis, clone MAMMA1001627, highly similar to Homo sapiens transcription factor TBX6 (Q9HA44_HUMAN)
- T-box transcription factor TBX6 (TBX6_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TBX6 Gene
Function for TBX6 Gene
Molecular function for TBX6 Gene
- UniProtKB/Swiss-Prot Function:
- T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
- GENATLAS Biochemistry:
- murine T-box gene Tbx6 (T,brachyury) homolog,expressed during gastrulation and in some adult tissues,including testis,involved in paraxial mesoderm formation and somitogenesis
Phenotypes From GWAS Catalog for TBX6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IBA | 21873635 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0001085 | RNA polymerase II transcription factor binding | ISS | -- |
| GO:0001102 | RNA polymerase II activating transcription factor binding | IBA,ISS | -- |
Phenotypes for TBX6 Gene
- MGI mutant phenotypes for TBX6:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for TBX6:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TBX6 - Select products 50% OFF >
- * TBX6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TBX6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBX6
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBX6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBX6
- Browse OriGene Inhibitory RNA Products For TBX6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBX6
Clone Products
- Applied Biological Materials (abm): Clones for TBX6 - Select products 50% OFF >
- * TBX6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TBX6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBX6
Cell Line Products
-
Horizon Cell Lines for TBX6
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for TBX6 Gene
Localization for TBX6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TBX6 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| extracellular | 2 |
| cytoskeleton | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IEA,IBA | 21873635 |
Pathways & Interactions for TBX6 Gene
Pathways by source for TBX6 Gene
3 BioSystems pathways for TBX6 Gene
1 R&D Systems pathway for TBX6 Gene
Interacting Proteins for TBX6 Gene
Selected Interacting proteins:
O95947-TBX6_HUMAN
ENSP00000378650
for TBX6 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for TBX6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | ISS | -- |
| GO:0001570 | vasculogenesis | IBA | -- |
| GO:0001707 | mesoderm formation | IEA | -- |
| GO:0001708 | cell fate specification | IBA | 21873635 |
| GO:0001947 | heart looping | IBA | 21873635 |
No data available for SIGNOR curated interactions for TBX6 Gene
Transcripts for TBX6 Gene
mRNA/cDNA for TBX6 Gene
- 2 REFSEQ mRNAs :
- 5 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000279386 1796 nts (view in UCSC)
- ENST00000395224 1803 nts (view in UCSC)
- ENST00000553607 2162 nts (view in UCSC)
- ENST00000567664 1543 nts (view in UCSC)
- ENST00000627355 1796 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TBX6 - Select products 50% OFF >
- * TBX6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TBX6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TBX6
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBX6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TBX6
- Browse OriGene Inhibitory RNA Products For TBX6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TBX6
Clone Products
- Applied Biological Materials (abm): Clones for TBX6 - Select products 50% OFF >
- * TBX6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TBX6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TBX6
Relevant External Links for TBX6 Gene
- GeneLoc Exon Structure for
- TBX6
Expression for TBX6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Primitive Streak (Early Embryonic Tissues)
- Primitive Streak Cells Primitive Streak
- Primitive Streak Cells Posterior Primitive Streak
-
Paraxial Mesoderm (Gastrulation Derivatives)
- Presegmented Somitic Mesenchyme Cells Presomitic Mesoderm
- Presomitic Mesoderm Cells Presomitic Mesoderm
-
Somite (Muscoskeletal System)
- Presegmented Somitic Mesenchyme Cells Presomitic Mesoderm
- Presomitic Mesoderm Cells Presomitic Mesoderm
-
Skeletal Muscle (Muscoskeletal System)
- Muscle Progenitor Cells Mandibular Arch Muscles
- Muscle Progenitor Cells Hyoid Arch Muscles
- NULL (Uncategorized)
-
Epiblast (Early Embryo)
- Primitive Streak Cells Posterior Primitive Streak
- Mesoderm (Gastrulation Derivatives)
mRNA differential expression in normal tissues according to GTEx for TBX6 Gene
This gene is overexpressed in Esophagus - Mucosa (x6.2).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TBX6
SOURCE GeneReport for Unigene cluster for TBX6 Gene:
Hs.198301mRNA Expression by UniProt/SwissProt for TBX6 Gene:
O95947-TBX6_HUMAN
Tissue specificity:
Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.
Evidence on tissue expression from TISSUES for TBX6 Gene
- Nervous system(4.4)
- Blood(4.3)
- Lymph node(4)
- Spleen(4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for TBX6 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- integumentary
- nervous
- respiratory
- skeletal muscle
- skeleton
Regions:
Head and neck:
- eye
- eyelid
- face
- head
- neck
- nose
- skull
Thorax:
- chest wall
- lung
- rib
- rib cage
- sternum
Pelvis:
- pelvis
General:
- skin
- spinal column
- spinal cord
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for TBX6
-
OriGene qPCR primer pairs and template standards for TBX6
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TBX6 Gene
Orthologs for TBX6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TBX6 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TBX6 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TBX6 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TBX6 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tbx6 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tbx6 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | TBX6 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TBX6 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TBX6 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | tbx6 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | Doc1 31 32 |
|
ManyToMany | |
| Doc3 31 32 |
|
ManyToMany | |||
| Doc2 31 32 |
|
ManyToMany |
- Species where no ortholog for TBX6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TBX6 Gene
- ENSEMBL:
- Gene Tree for TBX6 (if available)
- TreeFam:
- Gene Tree for TBX6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TBX6: view image
Paralogs for TBX6 Gene
Paralogs for TBX6 Gene
(15) SIMAP similar genes for TBX6 Gene using alignment to 2 proteins:
- TBX6_HUMAN
- Q9HA44_HUMAN
Variants for TBX6 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TBX6 Gene
| SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 694403 | Pathogenic: Scoliosis | 30,089,208(-) | C/T | MISSENSE_VARIANT | |
| 694404 | Likely Pathogenic: Scoliosis | 30,089,140(-) | C/A | MISSENSE_VARIANT | |
| 694405 | Uncertain Significance: Scoliosis | 30,089,124(-) | T/A | MISSENSE_VARIANT | |
| 694406 | Pathogenic: Scoliosis | 30,089,088(-) | T/TCCC | INFRAME_INSERTION | |
| 694407 | Uncertain Significance: Scoliosis | 30,089,065(-) | G/A | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758642 | CNV | gain | 17122850 |
| nsv1160384 | CNV | duplication | 26073780 |
| nsv833187 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
43.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.33;
41.57% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TBX6 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBX6 Gene
Disorders for TBX6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| spondylocostal dysostosis 5 |
|
|
| scoliosis |
|
|
| dysostosis |
|
|
| spondylocostal dysostosis 3, autosomal recessive |
|
|
| spondylocostal dysostosis, autosomal recessive |
|
|
Search TBX6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TBX6_HUMAN- Spondylocostal dysostosis 5 (SCDO5) [MIM:122600]: A rare condition of variable severity characterized by vertebral and costal anomalies. The main feature include dwarfism, vertebral fusion, hemivertebrae, posterior rib fusion, reduced rib number, and other rib malformations. SCDO5 inheritance can be autosomal dominant or recessive. {ECO:0000269 PubMed:23335591, ECO:0000269 PubMed:25564734}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for TBX6
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for TBX6 Gene
Publications for TBX6 Gene
- Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19. (PMID: 9888994) Yi CH … Brook JD (Genomics 1999) 2 3 4
- The human TBX6 gene: cloning and assignment to chromosome 16p11.2. (PMID: 9933572) Papapetrou C … Edwards YH (Genomics 1999) 2 3 4
- Compound Heterozygosity for Null Mutations and a Common Hypomorphic Risk Haplotype in TBX6 Causes Congenital Scoliosis. (PMID: 28054739) Takeda K … Ikegawa S (Human mutation 2017) 3 4
- TBX6 null variants and a common hypomorphic allele in congenital scoliosis. (PMID: 25564734) Wu N … Zhang F (The New England journal of medicine 2015) 3 4
- Autosomal dominant spondylocostal dysostosis is caused by mutation in TBX6. (PMID: 23335591) Sparrow DB … Dunwoodie SL (Human molecular genetics 2013) 3 4
ExternalLinks
Products for TBX6 Gene
- Custom Antibody ServicesOriGene Antibodies for TBX6
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- Custom Assay Services
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- OriGene qPCR primer pairs for TBX6
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- Sino Biological Antibodies for TBX6
- Browse Sino Biological Assays
- Browse Antibodies
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- Browse ELISA Kits
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- High-throughput Antibody Production Service
- Protein Production Service
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- Novus Biologicals Antibodies for TBX6
- Novus Biologicals proteins and lysates for TBX6
- Browse Antibodies
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- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for TBX6
- Abcam proteins for TBX6
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- Browse Primary Antibodies
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- Invitrogen Antibodies for TBX6 (AFLGC-TBX6)
- VectorBuilder Custom and pre-made DNA vectors for TBX6 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TBX6 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Stable cell line generation for TBX6
- antibodies-online: Show 21 available TBX6 Antibodies ranked by validation data
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- antibodies-online: Search results for available TBX6 related products ranked by validation data
- antibodies-online: Show 4 available TBX6 Proteins ranked by validation data
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- Quality Products:
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- Browse GeneCopoeia Cell Lines
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- Boster Bio Antibodies for TBX6
- Browse Boster Bio ELISA Kits
- Signalway Proteins for TBX6
Sources for TBX6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
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- (115) NCBI Bookshelf
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- (119) UDN
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- (122) ENCODE
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- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
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- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
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- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB