Aliases for TBX5-AS1 Gene

Subcategory (RNA class) for TBX5-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for TBX5-AS1 Gene

  • TBX5 Antisense RNA 1 2 3 5
  • TBX5-AS1 2 5 165
  • TBX5 Antisense RNA 1 (Non-Protein Coding) 2 3
  • NONHSAG012380.2 91
  • HSALNG0094210 164

External Ids for TBX5-AS1 Gene

Previous GeneCards Identifiers for TBX5-AS1 Gene

  • GC12P114845

Summaries for TBX5-AS1 Gene

GeneCards Summary for TBX5-AS1 Gene

TBX5-AS1 (TBX5 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TBX5-AS1 include Holt-Oram Syndrome.

Additional gene information for TBX5-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TBX5-AS1 Gene

Genomics for TBX5-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TBX5-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J114395 Promoter/Enhancer 1.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 600.7 -2.7 -2686 20.6 CTCF TEAD4 RFX5 PRDM1 POLR2A EZH2 NRF1 SP1 RFX1 ZSCAN29 TBX5 TBX5-AS1 LOC105369998 piR-60051-023 RBM19
GH12J114438 Enhancer 0.6 dbSUPER 11.8 +34.2 34169 6.8 CEBPG ZNF512 EZH2 EGR1 CEBPB ZFHX2 ZNF366 CBX8 HDAC2 CBFA2T3 TBX5 TBX5-AS1 LOC105369998 TBX3
GH12J114391 Enhancer 0.4 Ensembl dbSUPER 0.4 -16.5 -16472 0.2 EZH2 TBX5 TBX5-AS1 piR-60051-023 RBM19
GH12J114392 Enhancer 0.4 dbSUPER 0.4 -14.6 -14591 2.7 EZH2 SCRT2 RAD21 TBX5-AS1 TBX5 piR-60051-023 RBM19
GH12J114381 Enhancer 0.3 Ensembl dbSUPER 0.3 -26.2 -26214 0.5 TBX5 TBX5-AS1 piR-60051-023 RBM19
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TBX5-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TBX5-AS1 Gene

Genomic Locations for TBX5-AS1 Gene
chr12:114,408,173-114,412,832
(GRCh38/hg38)
Size:
4,660 bases
Orientation:
Plus strand
chr12:114,845,996-114,850,637
(GRCh37/hg19)
Size:
4,642 bases
Orientation:
Plus strand

Genomic View for TBX5-AS1 Gene

Genes around TBX5-AS1 on UCSC Golden Path with GeneCards custom track
TBX5-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
TBX5-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TBX5-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TBX5-AS1 Gene

Proteins for TBX5-AS1 Gene

Post-translational modifications for TBX5-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TBX5-AS1 Gene

Domains & Families for TBX5-AS1 Gene

Gene Families for TBX5-AS1 Gene

genes like me logo Genes that share domains with TBX5-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TBX5-AS1 Gene

Function for TBX5-AS1 Gene

Phenotypes From GWAS Catalog for TBX5-AS1 Gene

Phenotypes for TBX5-AS1 Gene

genes like me logo Genes that share phenotypes with TBX5-AS1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TBX5-AS1 Gene

Localization for TBX5-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TBX5-AS1 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TBX5-AS1 Gene

Pathways & Interactions for TBX5-AS1 Gene

PathCards logo

SuperPathways for TBX5-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TBX5-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TBX5-AS1 Gene

Drugs & Compounds for TBX5-AS1 Gene

No Compound Related Data Available

Transcripts for TBX5-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TBX5-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00001C6DF0_9606 lncRNA 766 4

Ensembl: ENST00000531024 (view in UCSC) ,

LncBook: HSALNT0195245,

LNCipedia: TBX5-AS1:4,

NONCODE: NONHSAT030878.2,

URS000013E742_9606 lncRNA 3620 3

Ensembl: ENST00000528549 (view in UCSC) ,

LNCipedia: TBX5-AS1:5,

NONCODE: NONHSAT030879.2,

URS000012248A_9606 lncRNA 961 3

Ensembl: ENST00000532697 (view in UCSC) ,

LncBook: HSALNT0195243, HSALNT0195244,

LNCipedia: TBX5-AS1:3,

URS00000F22F0_9606 lncRNA 822 3

Ensembl: ENST00000531202 (view in UCSC) ,

LncBook: HSALNT0195241,

LNCipedia: TBX5-AS1:1,

URS000075C09F_9606 lncRNA 3638 2

HGNC: 27402,

RefSeq: NR_038440,

TBX5-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TBX5-AS1 Gene

4 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for TBX5-AS1 Gene

No ASD Table

Relevant External Links for TBX5-AS1 Gene

GeneLoc Exon Structure for
TBX5-AS1

Expression for TBX5-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TBX5-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for TBX5-AS1 Gene

This gene is overexpressed in Heart - Atrial Appendage (x15.8), Lung (x9.3), Esophagus - Muscularis (x6.6), Heart - Left Ventricle (x6.0), and Esophagus - Gastroesophageal Junction (x4.0).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TBX5-AS1

SOURCE GeneReport for Unigene cluster for TBX5-AS1 Gene:

Hs.567915
genes like me logo Genes that share expression patterns with TBX5-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TBX5-AS1 Gene

Orthologs for TBX5-AS1 Gene

Evolution for TBX5-AS1 Gene

ENSEMBL:
Gene Tree for TBX5-AS1 (if available)
TreeFam:
Gene Tree for TBX5-AS1 (if available)

No data available for Orthologs for TBX5-AS1 Gene

Paralogs for TBX5-AS1 Gene

No data available for Paralogs for TBX5-AS1 Gene

Variants for TBX5-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TBX5-AS1 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
881338 Uncertain Significance: Holt-Oram syndrome 114,408,262(+) C/T NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT
881339 Uncertain Significance: Holt-Oram syndrome 114,408,278(+) G/A NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT
rs115599823 Benign: Holt-Oram syndrome 114,408,320(+) G/A
rs148864662 Benign: Holt-Oram syndrome 114,408,224(+) C/G NON_CODING_TRANSCRIPT_VARIANT
rs186960328 Benign: Holt-Oram syndrome 114,408,439(+) C/T

Additional dbSNP identifiers (rs#s) for TBX5-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for TBX5-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv455720 CNV loss 19166990
nsv560292 CNV loss 21841781
nsv832518 CNV loss 17160897
nsv952486 CNV deletion 24416366

Additional Variant Information for TBX5-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TBX5-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TBX5-AS1 Gene

Disorders for TBX5-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TBX5-AS1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
holt-oram syndrome
  • hos
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with TBX5-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TBX5-AS1 Gene

Publications for TBX5-AS1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3

Products for TBX5-AS1 Gene

Sources for TBX5-AS1 Gene