Aliases for TBRG1 Gene
External Ids for TBRG1 Gene
Previous GeneCards Identifiers for TBRG1 Gene
GeneCards Summary for TBRG1 Gene
TBRG1 (Transforming Growth Factor Beta Regulator 1) is a Protein Coding gene. Diseases associated with TBRG1 include Weill-Marchesani Syndrome and Splenic Abscess. Among its related pathways are ERK Signaling and TGF-Beta Pathway.
UniProtKB/Swiss-Prot Summary for TBRG1 Gene
Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.